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CASQ2

  • Official Full Name

    calsequestrin 2 (cardiac muscle)

  • Overview

    The protein encoded by this gene specifies the cardiac muscle family member of the calsequestrin family. Calsequestrin;is localized to the sarcoplasmic reticulum in cardiac and slow skeletal muscle cells. The protein is a calcium binding;protein that stores calcium for muscle function. Mutations in this gene cause stress-induced polymorphic ventricular;tachycardia, also referred to as catecholaminergic polymorphic ventricular tachycardia 2 (CPVT2), a disease;characterized by bidirectional ventricular tachycardia that may lead to cardiac arrest.
  • Synonyms

    CASQ2; calsequestrin 2 (cardiac muscle); calsequestrin-2; PDIB2; calsequestrin, cardiac muscle isoform; calsequestrin 2, fast-twitch, cardiac muscle; FLJ26321; FLJ93514;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Native Proteins
  • Canine
  • Chicken
  • Human
  • Mouse
  • Zebrafish
  • Dog Heart
  • E.coli
  • HEK293
  • HEK293T
  • Human
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • His|T7
  • Myc
  • DDK
  • MYC
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CASQ2-4248H Recombinant Human Calsequestrin 2 (Cardiac Muscle), His-tagged Human His
Human CASQ2-0436H Recombinant Human CASQ2 Protein, GST-Tagged Wheat Germ GST
Human CASQ2-7826HCL Recombinant Human CASQ2 293 Cell Lysate HEK293 N/A
Human CASQ2-6334H Recombinant Human CASQ2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human CASQ2-301241H Recombinant Human CASQ2 protein, GST-tagged E.coli GST Phe273-Glu399
Human CASQ2-2750HF Recombinant Full Length Human CASQ2 Protein, GST-tagged In Vitro Cell Free System GST 399 amino acids
Mouse CASQ2-2760M Recombinant Mouse CASQ2 Protein Mammalian Cell His
Mouse Casq2-775M Recombinant Mouse Casq2 Protein, MYC/DDK-tagged HEK293T MYC/DDK
Mouse Casq2-1745M Recombinant Mouse Casq2 protein, His & T7-tagged E.coli His/T7 Glu20~Lys320 (Accession # O09161)
Mouse CASQ2-1250M Recombinant Mouse CASQ2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse CASQ2-1250M-B Recombinant Mouse CASQ2 Protein Pre-coupled Magnetic Beads HEK293
Canine CASQ2-30C Native Canine CASQ2 Dog Heart N/A
Zebrafish CASQ2-789Z Recombinant Zebrafish CASQ2 Mammalian Cell His
Chicken CASQ2-6095C Recombinant Chicken CASQ2 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

CASQ2 involved in several pathways and played different roles in them. We selected most pathways CASQ2 participated on our site, such as Calcium Regulation in the Cardiac Cell, which may be useful for your reference. Also, other proteins which involved in the same pathway with CASQ2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Calcium Regulation in the Cardiac CellGNG13B;GJC1;GJA8;GJA3;CHRM5;CX35.4;RGS18;GJB2;ADRa1A

CASQ2 has several biochemical functions, for example, calcium ion binding, calcium-dependent protein binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CASQ2 itself. We selected most functions CASQ2 had, and list some proteins which have the same functions with CASQ2. You can find most of the proteins on our site.

Function Related Protein
calcium ion bindingC1S;CANX;DST;VIL1;TPM4;PCDH1G18;S100B;MMP8;PCDH1G2
calcium-dependent protein bindingFCN2;SLC9A1;VPS37B;NRXN1;CD209A;S100A1;DMBT1;DDX5;TNNC1
protein bindingRHO;UBA2;F8;CCT8;ADRM1;RSL24D1;TIMM8A;EIF4B;C19orf25
protein homodimerization activityPPP2R4;C6orf108;EXT1;PVRL2;APOA2;WHRN;COMMD1;GOT2;PON3
protein kinase C bindingPDLIM5;CASQ2;PRKCSH;TWF2;PKN1;IRS1;HDAC7A;DACT3;SDPR

CASQ2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CASQ2 here. Most of them are supplied by our site. Hope this information will be useful for your research of CASQ2.

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