• Official Full Name

    chemokine (C-C motif) ligand 13

  • Background

    This gene is one of several Cys-Cys (CC) cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for monocytes, lymphocytes, basophils and eosinophils, but not neutrophils. This chemokine plays a role in accumulation of leukocytes during inflammation. It may also be involved in the recruitment of monocytes into the arterial wall during artherosclerosis.
  • Synonyms

    CCL13; chemokine (C-C motif) ligand 13; NCC1; CKb10; MCP-4; NCC-1; SCYL1; SCYA13; MGC17134; C-C motif chemokine 13; CK-beta-10; OTTHUMP00000163804; new CC chemokine 1; small-inducible cytokine A13; monocyte chemotactic protein 4; monocyte chemoattractant protein 4; small inducible cytokine subfamily A (Cys-Cys), member 13; MCP4;
    • Type:
    • Recombinant Proteins
    • Cell & Tissue Lysates
    • Species :
    • Human
    • Source :
    • CHO
    • E.coli
    • HEK293
    • Human Cells
    • Wheat Germ
    • Yeast
    • Tag :
    • Biotin
    • Fc
    • GST
    • His
    • His|GST
    • N/A
    • N
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CCL13-432H Recombinant Human CCL13 protein, His-tagged Yeast His
    Human CCL13-288H Recombinant Human CCL13 protein E.coli N/A
    Human CCL13-241H Recombinant Human CCL13, His-tagged Yeast His
    Human CCL13-7734HCL Recombinant Human CCL13 293 Cell Lysate HEK293 N/A
    Human CCL13-0607H Recombinant Human CCL13 Protein, GST-Tagged Wheat Germ GST
    Human CCL13-278H Active Recombinant Human Chemokine (C-C Motif) Ligand 13, HIgG1 Fc-tagged CHO Fc
    Human CCL13-276H Active Recombinant Human Chemokine (C-C Motif) Ligand 13, MIgG2a Fc-tagged CHO Fc
    Human CCL13-2792H Recombinant Human Chemokine (C-C Motif) Ligand 13, His-tagged E.coli His
    Human CCL13-151H Recombinant Human CCL13 Protein, DYKDDDDK-tagged Human Cells DYKDDDDK
    Human CCL13-277H Active Recombinant Human Chemokine (C-C Motif) Ligand 13, HIgG1 Fc-tagged, mutant CHO Fc
    Human CCL13-195H Recombinant Human CCL13 protein E.coli N/A
    Human CCL13-221H Recombinant Human CCL13 Protein, His/GST-tagged E.coli His/GST
    Human CCL13-73H Recombinant Human CCL13 Protein E.coli
    Human CCL13-2729H Recombinant Human CCL13 Protein, His-tagged E.coli N-His
    Human CCL13-078C Recombinant Human CCL13 Protein (75 aa) E.coli
    Human CCL13-84H Recombinant Human CCL13 Protein, Biotin-tagged E.coli Biotin
    Human CCL13-1031H Recombinant Human CCL13 Protein (Gln24-Thr98), GST tagged E.coli GST
    Human CCL13-09H Recombinant Human CCL13 Protein E.coli
    Human CCL13-1308H Recombinant Human CCL13 Protein (Gln24-Thr98), N-GST tagged E.coli N-GST
    • Involved Pathway
    • Protein Function
    • Interacting Protein
    • CCL13 Related Articles
    • CCL13 Related Gene Family
    • CCL13 Related Research Area

    CCL13 involved in several pathways and played different roles in them. We selected most pathways CCL13 participated on our site, such as Cytokine-cytokine receptor interaction, Chemokine signaling pathway, NF-kappa B signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with CCL13 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cytokine-cytokine receptor interactionTNFRSF13B;HGF;IFNK;CCR5;CSH;IL7;CCR3;CCR8;TNFSF10
    Chemokine signaling pathwayCCL3;RHOA;GRK4;NFKBIA;VAV3;CXCR1;GNG7;ITK;WASL
    NF-kappa B signaling pathwayLRDD;DDX58;CD40LG;TRAF3;CCL21B;BCL10;Ccl21c;TRAF2;TRAF5

    CCL13 has several biochemical functions, for example, CCR chemokine receptor binding, chemokine activity, receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CCL13 itself. We selected most functions CCL13 had, and list some proteins which have the same functions with CCL13. You can find most of the proteins on our site.

    Function Related Protein
    CCR chemokine receptor bindingXCL2;CCL24;CCL44;CCL14;CCL13;CCL20;CCRL2;CCL16;CCL35.1
    chemokine activityCXCL8B.3;CXCL19;CCL25B;CCL28;CCL18;CCL3L1;Ccl9;CCL11;CCL44

    CCL13 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CCL13 here. Most of them are supplied by our site. Hope this information will be useful for your research of CCL13.


    Agrawal, S; Townley, RG; et al. Role of periostin, FENO, IL-13, lebrikzumab, other IL-13 antagonist and dual IL-4/IL-13 antagonist in asthma. EXPERT OPINION ON BIOLOGICAL THERAPY 14:165-181(2014).
    Lechner, CJ; Gantin, RG; et al. Chemokines and cytokines in patients with an occult Onchocerca volvulus infection. MICROBES AND INFECTION 14:438-446(2012).
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