CCL13
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Official Full Name
chemokine (C-C motif) ligand 13
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Background
This gene is one of several Cys-Cys (CC) cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for monocytes, lymphocytes, basophils and eosinophils, but not neutrophils. This chemokine plays a role in accumulation of leukocytes during inflammation. It may also be involved in the recruitment of monocytes into the arterial wall during artherosclerosis. -
Synonyms
CCL13; chemokine (C-C motif) ligand 13; NCC1; CKb10; MCP-4; NCC-1; SCYL1; SCYA13; MGC17134; C-C motif chemokine 13; CK-beta-10; OTTHUMP00000163804; new CC chemokine 1; small-inducible cytokine A13; monocyte chemotactic protein 4; monocyte chemoattractant protein 4; small inducible cytokine subfamily A (Cys-Cys), member 13; MCP4;
- Involved Pathway
- Protein Function
- Interacting Protein
- CCL13 Related Articles
- CCL13 Related Gene Family
- CCL13 Related Research Area
CCL13 involved in several pathways and played different roles in them. We selected most pathways CCL13 participated on our site, such as Cytokine-cytokine receptor interaction, Chemokine signaling pathway, NF-kappa B signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with CCL13 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Cytokine-cytokine receptor interaction | TNFRSF13B;HGF;IFNK;CCR5;CSH;IL7;CCR3;CCR8;TNFSF10 |
| Chemokine signaling pathway | CCL3;RHOA;GRK4;NFKBIA;VAV3;CXCR1;GNG7;ITK;WASL |
| NF-kappa B signaling pathway | LRDD;DDX58;CD40LG;TRAF3;CCL21B;BCL10;Ccl21c;TRAF2;TRAF5 |
CCL13 has several biochemical functions, for example, CCR chemokine receptor binding, chemokine activity, receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CCL13 itself. We selected most functions CCL13 had, and list some proteins which have the same functions with CCL13. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| CCR chemokine receptor binding | XCL2;CCL24;CCL44;CCL14;CCL13;CCL20;CCRL2;CCL16;CCL35.1 |
| chemokine activity | CXCL8B.3;CXCL19;CCL25B;CCL28;CCL18;CCL3L1;Ccl9;CCL11;CCL44 |
| receptor binding | CX3CL1;SRMS;GDNF;PAOX;UFD1L;GSTM7;CSNK2B;ADCYAP1;ECH1 |
CCL13 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CCL13 here. Most of them are supplied by our site. Hope this information will be useful for your research of CCL13.
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