ccl13

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ccl13

Official Full Name chemokine (C-C motif) ligand 13
Background This gene is one of several Cys-Cys (CC) cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for monocytes, lymphocytes, basophils and eosinophils, but not neutrophils. This chemokine plays a role in accumulation of leukocytes during inflammation. It may also be involved in the recruitment of monocytes into the arterial wall during artherosclerosis.
Synonyms CCL13; chemokine (C-C motif) ligand 13; NCC1; CKb10; MCP-4; NCC-1; SCYL1; SCYA13; MGC17134; C-C motif chemokine 13; CK-beta-10; OTTHUMP00000163804; new CC chemokine 1; small-inducible cytokine A13; monocyte chemotactic protein 4; monocyte chemoattractant protein 4; small inducible cytokine subfamily A (Cys-Cys), member 13; MCP4
    • Species :
    • Human
    • Source :
    • CHO
    • E.coli
    • HEK293
    • Human Cells
    • Wheat Germ
    • Yeast
    • Tag :
    • DYKDDDDK
    • Fc
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CCL13-151H Recombinant Human CCL13 Protein, DYKDDDDK-tagged Human Cells DYKDDDDK
    Human CCL13-0607H Recombinant Human CCL13 Protein, GST-Tagged Wheat Germ GST
    Human CCL13-195H Recombinant Human CCL13 protein E.coli N/A
    Human CCL13-221H Recombinant Human CCL13 Protein, His/GST-tagged E.coli His/GST
    Human CCL13-241H Recombinant Human CCL13, His-tagged Yeast His
    Human CCL13-276H Recombinant Human Chemokine (C-C Motif) Ligand 13, MIgG2a Fc-tagged CHO Fc
    Human CCL13-277H Recombinant Human Chemokine (C-C Motif) Ligand 13, HIgG1 Fc-tagged, mutant CHO Fc
    Human CCL13-278H Recombinant Human Chemokine (C-C Motif) Ligand 13, HIgG1 Fc-tagged CHO Fc
    Human CCL13-2792H Recombinant Human Chemokine (C-C Motif) Ligand 13, His-tagged E.coli His
    Human CCL13-288H Recombinant Human CCL13 protein E.coli N/A
    Human CCL13-432H Recombinant Human CCL13 protein, His-tagged Yeast His
    Human CCL13-7734HCL Recombinant Human CCL13 293 Cell Lysate HEK293 N/A

    ccl13 involved in several pathways and played different roles in them. We selected most pathways ccl13 participated on our site, such as Cytokine-cytokine receptor interaction, Chemokine signaling pathway, NF-kappa B signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with ccl13 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cytokine-cytokine receptor interaction IL17B; GM10591; IFNAR1; IL2RA; IL10RB; IL21R.1; KITLGA; IL12RB2; TNFRSF10B; KIT
    Chemokine signaling pathway CCL24; ADRBK1; GNAI2; CCL11; PAK1; LYN; MAPK1; CCL13; CXCL13; VAV1
    NF-kappa B signaling pathway PLCG1; BIRC2; TRADD; CCL4L1; TAB2; Ccl21c; SYK; Bcl2a1b; TLR4; PRKCB

    ccl13 has several biochemical functions, for example, CCR chemokine receptor binding, chemokine activity, receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ccl13 itself. We selected most functions ccl13 had, and list some proteins which have the same functions with ccl13. You can find most of the proteins on our site.

    Function Related Protein
    CCR chemokine receptor binding CCL35.1; CCL1; CCL19A.1; XCL2; CCL18; CCL16; CCL34B.4; CCL24; CCRL2; CCL34A.4
    chemokine activity CCL26; CXCL2; CXL34B.11; CCL35.2; CCL7; CCL25; CXCL12A; CCL28; CCL44; CXCL16
    receptor binding HAND2; ARPP19A; MSTN; CCL13; DRD1A; WNT7AA; GUSB; NPFFL; NTF7; Fert2

    ccl13 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ccl13 here. Most of them are supplied by our site. Hope this information will be useful for your research of ccl13.

    HNRNPH3

    Agrawal, S; Townley, RG; et al. Role of periostin, FENO, IL-13, lebrikzumab, other IL-13 antagonist and dual IL-4/IL-13 antagonist in asthma. EXPERT OPINION ON BIOLOGICAL THERAPY 14:165-181(2014).
    Lechner, CJ; Gantin, RG; et al. Chemokines and cytokines in patients with an occult Onchocerca volvulus infection. MICROBES AND INFECTION 14:438-446(2012).

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