CCL26

  • Official Full Name

    chemokine (C-C motif) ligand 26

  • Background

    This gene is one of two Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 7. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for normal peripheral blood eosinophils and basophils. The product of this gene is one of three related chemokines that specifically activate chemokine receptor CCR3. This chemokine may contribute to the eosinophil accumulation in atopic diseases.
  • Synonyms

    CCL26; chemokine (C-C motif) ligand 26; SCYA26, small inducible cytokine subfamily A (Cys Cys), member 26; C-C motif chemokine 26; CC chemokine IMAC; chemokine N1; eotaxin 3; IMAC; macrophage inflammatory protein 4 alpha; MIP 4a; MIP 4alpha; small inducible cytokine A26; thymic stroma chemokine 1; TSC 1; CCL 26; CCL26_HUMAN; Chemokine (C C motif) ligand 26; Eotaxin-3; macrophage inflammatory protein 4-alpha; MIP-4-alpha; MIP4a; MIP4alpha; SCYA 26; SCYA26; Small inducible cytokine subfamily A (Cys Cys) member 26; Small inducible cytokine subfamily A member 26; Small-inducible cytokine A26; Thymic stroma chemokine-1; TSC-1; TSC1; OTTHUMP00000160954; OTTHUMP00000210227; small inducible c; MIP-4a; MIP-4alpha;
    • Type:
    • Recombinant Proteins
    • Cell & Tissue Lysates
    • Species :
    • Human
    • Source :
    • Baculovirus-Insect Cells
    • E.coli
    • HEK293
    • Human Cells
    • Wheat Germ
    • Tag :
    • Biotin
    • GST
    • His
    • His|GST
    • N/A
    • N
    • Tag Free
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CCL26-023H Recombinant Human CCL26 Protein, His-tagged E.coli His
    Human CCL26-26161TH Recombinant Human CCL26 E.coli N/A
    Human CCL26-7725HCL Recombinant Human CCL26 293 Cell Lysate HEK293 N/A
    Human CCL26-10847H Recombinant Human CCL26, GST-tagged E.coli GST
    Human CCL26-21H Recombinant Human CCL26 Protein E.coli
    Human CCL26-26912TH Recombinant Human CCL26 E.coli N/A
    Human CCL26-0631H Recombinant Human CCL26 Protein, GST-Tagged Wheat Germ GST
    Human CCL26-72H Recombinant Human Chemokine (C-C motif) Ligand 26 E.coli N/A
    Human CCL26-127C Recombinant Human CCL26 Protein (71 aa) E.coli
    Human CCL26-608H Recombinant Human CCL26 protein E.coli N/A
    Human CCL26-52H Recombinant Human CCL26 Protein E.coli
    Human CCL26-151H Recombinant Human CCL26 Protein, His-tagged Human Cells His
    Human CCL26-0877H Recombinant Human CCL26 Protein (Ser27-Leu94), GST tagged E.coli GST
    Human CCL26-468H Recombinant Human Chemokine (C-C motif) Ligand 26 E.coli N/A
    Human CCL26-22H Recombinant Active Human CCL26 Protein, Tag Free E.coli Tag Free
    Human CCL26-244H Recombinant Human CCL26 Protein, His/GST-tagged E.coli His/GST
    Human CCL26-0876H Recombinant Human CCL26 Protein (Ser27-Leu94), N-GST tagged E.coli N-GST
    Human CCL26-025H Recombinant Human CCL26 protein (Met1-Leu94) Baculovirus-Insect Cells
    Human CCL26-66H Recombinant Human CCL26 Protein, Biotin-tagged E.coli Biotin
    • Involved Pathway
    • Protein Function
    • Interacting Protein
    • CCL26 Related Articles
    • CCL26 Related Gene Family
    • CCL26 Related Research Area

    CCL26 involved in several pathways and played different roles in them. We selected most pathways CCL26 participated on our site, such as Chemokine signaling pathway, Cytokine-cytokine receptor interaction, IL4-mediated signaling events, which may be useful for your reference. Also, other proteins which involved in the same pathway with CCL26 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Chemokine signaling pathwayPF4V1;SHC2;CX3CR1;CCL26;NFKB1;CCL19;CX3CL1;CCL3L3;CCL24
    Cytokine-cytokine receptor interactionIL17B;IL6R;FAS;EPOR;CD70;CCL19B;IL10;CXCL13;IL12A
    IL4-mediated signaling eventsEGR2;IRF4;CCL26;TFF3;RETNLB;MYB;PARP14;NIPAL1;IgG3

    CCL26 has several biochemical functions, for example, CCR chemokine receptor binding, chemokine activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CCL26 itself. We selected most functions CCL26 had, and list some proteins which have the same functions with CCL26. You can find most of the proteins on our site.

    Function Related Protein
    CCR chemokine receptor bindingCCL38.1;CCL44;CCL20;CCL19;XCL2;CCL34B.1;CCL19B;CCL17;CCL19A.2
    chemokine activityCCL3L1;CXCL12B;CCL20;CXCL13;CXCL2;CCL20B;CCL7;CXCL14;CCL21

    CCL26 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CCL26 here. Most of them are supplied by our site. Hope this information will be useful for your research of CCL26.

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    Sugaya, M; et al. Chemokines and Skin Diseases. ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS 63:109-115(2015).
    Huang, XS; Gruner, B; et al. Distinctive cytokine, chemokine, and antibody responses in Echinococcus multilocularis-infected patients with cured, stable, or progressive disease. MEDICAL MICROBIOLOGY AND IMMUNOLOGY 203:185-193(2014).
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