Recombinant Human Chemokine (C-C motif) Ligand 26

• Cat.No.: CCL26-468H
• Product Overview: CCL26 was expressed in E. coli and purifed by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer. MW: 8.5 kDa.

Specification

• Description: CCL26 is a small cytokine belonging to the CC chemokine family that is also known as thymus and activation regulated chemokine. This protein is involved in immunoregulatory and inflammatory processes. It is expressed constitutively in thymus, but only transiently in phytohemagglutinin-stimulated peripheral blood mononuclear cells.
• Source: E. coli
• Species: Human
• Tag: N/A
• Form: Liquid. In Phosphate Buffered Saline pH 7.4 containing 10% glycerol.
• Molecular Mass: 8.5 kDa (72aa), confirmed by MALDI-TOF (molecular weight on SDS-PAGE will appear higher).
• Protein length: 24-94aa
• AA Sequence: MTRGSDISKT CCFQYSHKPL PWTWVRSYEF TSNSCSQRAV IFTTKRGKKV CTHPRKKWVQ KYISLLKTPK QL
• Endotoxin: < 1.0 eu per 1 μg of protein (determined by lal
• Purity: >90% by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Concentration: 0.5 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: CCL26 chemokine (C-C motif) ligand 26 [ Homo sapiens ]
• Official Symbol: CCL26
• Synonyms: CCL26; chemokine (C-C motif) ligand 26; SCYA26, small inducible cytokine subfamily A (Cys Cys), member 26; C-C motif chemokine 26; CC chemokine IMAC; chemokine N1; eotaxin 3; IMAC; macrophage inflammatory protein 4 alpha; MIP 4a; MIP 4alpha; small inducible cytokine A26; thymic stroma chemokine 1; TSC 1; eotaxin-3; MIP-4-alpha; thymic stroma chemokine-1; small-inducible cytokine A26; macrophage inflammatory protein 4-alpha; small inducible cytokine subfamily A (Cys-Cys), member 26; TSC-1; MIP-4a; SCYA26; MIP-4alpha; MGC126714
• Gene ID: 10344
• mRNA Refseq: NM_006072
• Protein Refseq: NP_006063
• MIM: 604697
• UniProt ID: Q9Y258
• Chromosome Location: 7q11.2
• Pathway: Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; IL4-mediated signaling events, organism-specific biosystem
• Function: chemokine activity