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  • Official Full Name

    CD1b molecule

  • Overview

    This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail, and requires vesicular acidification to bind lipid antigens.
  • Synonyms

    CD1B; CD1b molecule; CD1, CD1b antigen , CD1B antigen, b polypeptide; T-cell surface glycoprotein CD1b; CD1B antigen, b polypeptide; cortical thymocyte antigen CD1B; differentiation antigen CD1-alpha-3; R1; CD1; CD1A; MGC125990; MGC125991;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Homo sapiens (Human)
  • Human
  • Rhesus
  • Rhesus Macaque
  • E.coli
  • E.coli expression system
  • HEK293
  • HEK293T
  • Human Cell
  • Human Cells
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • C
  • Fc
  • hFc
  • His
  • GST
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • Myc|DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CD1B-344H Recombinant Human CD1b molecule, His-tagged E.coli His
Human CD1B-0734H Recombinant Human CD1B Protein, GST-Tagged Wheat Germ GST
Human CD1B-27865TH Recombinant Human CD1B Wheat Germ N/A 333 amino acids
Human CD1B-27106TH Recombinant Human CD1B Wheat Germ N/A 92 amino acids
Human CD1B-7331H Recombinant Human CD1B protein(Met1-Ser303), hFc-tagged HEK293 C-hFc Met1-Ser303
Human CD1B & B2M-249H Recombinant Human CD1B & B2M protein(Met1-Ser303 & Met1-Met119), His-tagged HEK293 C-His Met1-Ser303 & Met1-Met119
Human CD1B-10918H Recombinant Human CD1B, His-tagged E.coli His 124-206a.a.
Human CD1B & B2M-001HCL Recombinant Human CD1B & B2M cell lysate Human Cell N/A
Human CD1B-1504HCL Recombinant Human CD1B cell lysate Human Cell N/A
Human CD1B-1211H Recombinant Human CD1B Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human CD1B-151H Recombinant Human CD1B Protein, His-tagged Human Cells His
Human CD1B-3039H Recombinant Human CD1B Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human CD1b-0915H Recombinant Human CD1b Protein (Ser18-Ser303), N-His tagged E.coli N-His Ser18-Ser303
Human CD1B-61HF Recombinant Full Length Human CD1B Protein In Vitro Cell Free System 333 amino acids
Human CD1B-3009HF Recombinant Full Length Human CD1B Protein, GST-tagged In Vitro Cell Free System GST 333 amino acids
Human CD1B-5277H Recombinant Human CD1B Protein (Met1-Ser303), C-Fc tagged Mammalian cells C-Fc Met1-Ser303
Human CD1B-164H Recombinant Human CD1B Protein, C-His-tagged E.coli C-His
Homo sapiens (Human) RFL35963HF Recombinant Full Length Human T-Cell Surface Glycoprotein Cd1B(Cd1B) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (18-333)
Rhesus CD1B-317R Recombinant Rhesus CD1B Protein, His-tagged HEK293 His Met1-Ser303
Rhesus Macaque CD1B-721R Recombinant Rhesus monkey CD1B Protein, His-tagged Mammalian Cell His
Rhesus Macaque CD1B-548R-B Recombinant Rhesus Macaque CD1B Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque CD1B-548R Recombinant Rhesus Macaque CD1B Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Chicken CD1B-2186C Recombinant Chicken CD1B Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

CD1B involved in several pathways and played different roles in them. We selected most pathways CD1B participated on our site, such as Hematopoietic cell lineage, which may be useful for your reference. Also, other proteins which involved in the same pathway with CD1B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Hematopoietic cell lineageFlt3l;CD1B;ITGA1;ITGA6;Cd24a;IL5;IL1R1;ITGA3;CD59A

CD1B has several biochemical functions, for example, beta-2-microglobulin binding, endogenous lipid antigen binding, exogenous lipid antigen binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CD1B itself. We selected most functions CD1B had, and list some proteins which have the same functions with CD1B. You can find most of the proteins on our site.

Function Related Protein
beta-2-microglobulin bindingCD1B;HFE;H2-Q10;CD1d1;FCGRT;HLA-E;CD1A;HLA-A;CD1D
endogenous lipid antigen bindingCD1C;CD1E;CD1B;CD1D;CD1A;CD1D2;CD1d1
exogenous lipid antigen bindingCD1d1;CD1D;CD1B;CD1E;CD1C;CD1D2;CD1A
lipopeptide bindingCD1E;TLR6;CD1D2;CD1C;CD1D;CD1d1;CD1A;CD1B

CD1B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CD1B here. Most of them are supplied by our site. Hope this information will be useful for your research of CD1B.


Research Area

Related articles

Romero-Palomo, F; Risalde, MA; et al. Immunohistochemical Detection of Dendritic Cell Markers in Cattle. VETERINARY PATHOLOGY 50:1099-1108(2013).
Kalantari-Dehaghi, M; Anhalt, GJ; et al. Pemphigus Vulgaris Autoantibody Profiling by Proteomic Technique. PLOS ONE 8:-(2013).
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