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Official Full Name CD1b molecule
Background This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail, and requires vesicular acidification to bind lipid antigens.
Synonyms CD1B; CD1b molecule; CD1, CD1b antigen , CD1B antigen, b polypeptide; T-cell surface glycoprotein CD1b; CD1B antigen, b polypeptide; cortical thymocyte antigen CD1B; differentiation antigen CD1-alpha-3; R1; CD1; CD1A; MGC125990; MGC125991
    • Species :
    • Chicken
    • Human
    • Rhesus
    • Rhesus Macaque
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Human Cell
    • Human Cells
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • Fc
    • GST
    • His
    • Myc/DDK
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CD1B-151H Recombinant Human CD1B Protein, His-tagged Human Cells His
    Human CD1B & B2M-001HCL Recombinant Human CD1B & B2M cell lysate Human Cell N/A
    Human CD1B & B2M-249H Recombinant Human CD1B & B2M protein, His-tagged HEK293 His
    Human CD1B-0734H Recombinant Human CD1B Protein, GST-Tagged Wheat Germ GST
    Human CD1B-10918H Recombinant Human CD1B, His-tagged E.coli His
    Human CD1B-1211H Recombinant Human CD1B Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human CD1B-1504HCL Recombinant Human CD1B cell lysate Human Cell N/A
    Human CD1B-27106TH Recombinant Human CD1B Wheat Germ N/A
    Human CD1B-27865TH Recombinant Human CD1B Wheat Germ N/A
    Human CD1B-3039H Recombinant Human CD1B Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human CD1B-344H Recombinant Human CD1b molecule, His-tagged E.coli His
    Human CD1B-7331H Recombinant Human CD1B, Fc tagged Human Cell Fc
    Rhesus CD1B-317R Recombinant Rhesus CD1B Protein, His-tagged HEK293 His
    Rhesus Macaque CD1B-721R Recombinant Rhesus monkey CD1B Protein, His-tagged Mammalian Cell His
    Chicken CD1B-2186C Recombinant Chicken CD1B Mammalian Cell His

    cd1b involved in several pathways and played different roles in them. We selected most pathways cd1b participated on our site, such as Hematopoietic cell lineage, which may be useful for your reference. Also, other proteins which involved in the same pathway with cd1b were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Hematopoietic cell lineage CD3E; CD3D; GP5; CD38; ANPEP; IL9R; FCGR1; GP1BB; Itga10&Itgb1; CD1E; FLT3

    cd1b has several biochemical functions, for example, beta-2-microglobulin binding, endogenous lipid antigen binding, exogenous lipid antigen binding. Some of the functions are cooperated with other proteins, some of the functions could acted by cd1b itself. We selected most functions cd1b had, and list some proteins which have the same functions with cd1b. You can find most of the proteins on our site.

    Function Related Protein
    beta-2-microglobulin binding FCGRT; HLA-A; HLA-E; CD1E; HFE; CD1A; CD1B; CD1d1; H2-Q10; CD1D
    endogenous lipid antigen binding CD1C; CD1E; CD1d1; CD1B; CD1A; CD1D; CD1D2
    exogenous lipid antigen binding CD1C; CD1A; CD1D; CD1D2; CD1B; CD1d1; CD1E
    lipopeptide binding CD1d1; CD1C; CD1A; CD1D2; TLR6; CD1B; CD1D; CD1E
    protein binding SHFM1; ZNF581; LSM6; HOXA5; TEN1; ZNF394; EIF2A; C19orf57; PTPN14; HPCAL4

    cd1b has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with cd1b here. Most of them are supplied by our site. Hope this information will be useful for your research of cd1b.


    Romero-Palomo, F; Risalde, MA; et al. Immunohistochemical Detection of Dendritic Cell Markers in Cattle. VETERINARY PATHOLOGY 50:1099-1108(2013).
    Kalantari-Dehaghi, M; Anhalt, GJ; et al. Pemphigus Vulgaris Autoantibody Profiling by Proteomic Technique. PLOS ONE 8:-(2013).

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