CD1B
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Official Full Name
CD1b molecule
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Overview
This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail, and requires vesicular acidification to bind lipid antigens. -
Synonyms
CD1B; CD1b molecule; CD1, CD1b antigen , CD1B antigen, b polypeptide; T-cell surface glycoprotein CD1b; CD1B antigen, b polypeptide; cortical thymocyte antigen CD1B; differentiation antigen CD1-alpha-3; R1; CD1; CD1A; MGC125990; MGC125991;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Chicken
- Homo sapiens (Human)
- Human
- Rhesus
- Rhesus Macaque
- E.coli
- E.coli expression system
- HEK293
- HEK293T
- Human Cell
- Human Cells
- In Vitro Cell Free System
- Mammalian Cell
- Mammalian cells
- Wheat Germ
- Fc
- GST
- His
- Avi
- Myc
- DDK
- Non
- Involved Pathway
- Protein Function
- Interacting Protein
- Other Resource
CD1B involved in several pathways and played different roles in them. We selected most pathways CD1B participated on our site, such as Hematopoietic cell lineage, which may be useful for your reference. Also, other proteins which involved in the same pathway with CD1B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Hematopoietic cell lineage | IL2RA;Itgam&Itgb2;ITGAM;CD36;Il6ra;ITGA1;IL3RA;CD59;CD1E |
CD1B has several biochemical functions, for example, beta-2-microglobulin binding, endogenous lipid antigen binding, exogenous lipid antigen binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CD1B itself. We selected most functions CD1B had, and list some proteins which have the same functions with CD1B. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| beta-2-microglobulin binding | FCGRT;CD1C;CD1B;CD1D;CD1D2;HLA-E;CD1d1;CD1E;HLA-A |
| endogenous lipid antigen binding | CD1C;CD1E;CD1d1;CD1A;CD1D;CD1D2;CD1B |
| exogenous lipid antigen binding | CD1d1;CD1E;CD1C;CD1A;CD1B;CD1D;CD1D2 |
| lipopeptide binding | CD1d1;CD1A;CD1D;CD1D2;CD1B;CD1E;TLR6;CD1C |
| protein binding | ELMO1;NSG1;GADD45B;SYT4;UPF3A;ITPRIPL1;TRMT112;DDIT3;MEP1B |
CD1B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CD1B here. Most of them are supplied by our site. Hope this information will be useful for your research of CD1B.
B2M
Research Area
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