|Official Full Name||CD226 antigen|
|Background||DNAM-1 (CD226) is a ~65 kD glycoprotein expressed on cell surface of T cells, NK cells, monocytes/macrophages, platelets and megakaryocytes and a subset of B cells and a member of the immunoglobulin (Ig)-superfamily containing 2 Ig-like domains of the V-s|
|Synonyms||CD226; CD226 antigen; platelet and T cell activation antigen 1; platelet and T-cell activation antigen 1; Pta1; DNAM1; DNAM-1; TLiSA1; BC051526|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
cd226 involved in several pathways and played different roles in them. We selected most pathways cd226 participated on our site, such as Adaptive Immune System, Cell adhesion molecules (CAMs), Immune System, which may be useful for your reference. Also, other proteins which involved in the same pathway with cd226 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Adaptive Immune System||CD300E; ACTR1B; KLHL20; DYNLL2; KIF11; RASGRP1; DYNC1I2; RNF123; CD300LB; ITGB1B.1|
|Cell adhesion molecules (CAMs)||CDH1; MHC2A; H2-Q10; NEO1; Ntng2; CD274; CADM1; SDC1; HLA-DRA; ICAM1|
|Immune System||MGC174155; NA; KIF11; TNRC5; CD207; CLEC4A; B2ML; CTSK; TNIP2; GBP6|
|Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell||KLRF1; CRTAM; CD300LH; AF251705; CLEC2B; CD300A; CD200R2; ICAM4; CXADR; LILRA2|
cd226 has several biochemical functions, for example, cell adhesion molecule binding, integrin binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by cd226 itself. We selected most functions cd226 had, and list some proteins which have the same functions with cd226. You can find most of the proteins on our site.
|cell adhesion molecule binding||SDCBP; FGG; NLGN1; CD226; PVRL2; VCAM1; ITGB7; ITGAL; PVRL3; SELL|
|integrin binding||COL4A3; ICAM2; SRC; SFRP2; ANGPTL3; ADAM22; ITGB1BP1; ACTN3; ICAM1; COL5A1|
|protein binding||VEGFA; CDK8; CTSL2; ZNF559; JPH2; EGF; MMP15; AHSA2; GATAD2B; TNFRSF11A|
|protein homodimerization activity||KLRB1B; PRMT8; ADRB3; GSTM1; ATPIF1A; PKD2; GYS2; HNF4A; SFTPC; EPHX2|
|protein kinase binding||RCC2; IBTK; LATS1; DPYSL2; SMAD1; KCNA5; CD226; GDF3; PPP1R12C; PRKAG1|
|receptor activity||KLRB1F; IGF2R; APLNR; VMN1R48; LILRB2; CSF2RA; NLGN3; PVRL2L; Tnfrsf22; PAQR5B|
cd226 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with cd226 here. Most of them are supplied by our site. Hope this information will be useful for your research of cd226.
TIGIT; PVR; PVRL2