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CD300A

Official Full Name

CD300a Molecule
Overview

Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. This gene encodes a beta subunit. Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene.
Synonyms

CMRF35-like molecule 8; CD300a antigen; CMRF35H9; OTTHUMP00000070877; OTTHUMP00000070878; OTTHUMP00000070879; NK inhibitory receptor; Irp60; leukocyte membrane antigen; inhibitory receptor protein 60; CD300 antigen-like family member A; immunoglobulin superfamily member 12; IgSF12; CMRF35H leukocyte immunoglobulin-like receptor; IRC1; IRC2; CLM-8; CMRF35H; CMRF-35H; CMRF35-H; CD300A; CMRF35-H9; IRC1/IRC2; CMRF-35-H9; CD300a molecule;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Chicken
Human
Leu18-Gln178
Mouse
Rattus norvegicus (Rat)
Rhesus monkey

Source

C-His
E.coli
E.coli expression system
HEK293
Human Cell
In Vitro Cell Free System
Mammalian Cell
Mammalian cells
Wheat Germ

Tag

Fc
GST
hIgG4
His
Avi
Non

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	CD300A-0776H	Recombinant Human CD300A Protein	Wheat Germ	Non		Inquiry
Human	CD300A-267H	Recombinant Human CD300A protein, Fc-tagged	HEK293	Fc	Leu18-Gln178	Inquiry
Human	CD300A-3976H	Recombinant Human CD300A, His tagged	HEK293	His	Met 1-Gln 178	$498 / 50 µg
Human	CD300A-15876H	Recombinant Human CD300A protein, His-tagged	HEK293	His	Leu 18 - Ser 128	Inquiry
Human	CD300A-0777H	Recombinant Human CD300A Protein, GST-Tagged	Wheat Germ	GST		Inquiry
Human	CD300A-054H	Recombinant Human CD300A Protein, Fc/HIS-tagged	HEK293	His&Fc		Inquiry
Human	CD300A-932HCL	Recombinant Human CD300A cell lysate	Human Cell	Non		Inquiry
Human	CD300A-1266H	Recombinant Human CD300A Protein, His&GST-tagged	E.coli	His&GST	Gln35-Ser274	Inquiry
Human	CD300A-3099HF	Recombinant Full Length Human CD300A Protein, GST-tagged	In Vitro Cell Free System	GST	299 amino acids	Inquiry
Human	CD300A-3098HF	Recombinant Full Length Human CD300A Protein	In Vitro Cell Free System		793 amino acids	Inquiry
Human	CD300A-147H	Recombinant Human CD300A Protein, Fc-tagged	HEK293	Fc	299	Inquiry
Human	CD300A-3979H	Recombinant Human CD300A Protein (Met1-Gln178), C-His tagged	Mammalian cells	His	Met1-Gln178	Inquiry
Human	CD300A-015H	Recombinant Human CD300A Protein, His-tagged	E.coli	His		Inquiry
Human	CD300A-126H	Recombinant Human CD300A protein, hFc&His-tagged	HEK293	His&Fc	Leu 18 - Gln 178	Inquiry
Mouse	Cd300a-456M	Active Recombinant Mouse Cd300a, Fc Chimera	Mammalian cells	Fc		Inquiry
Mouse	Cd300a-5168M	Recombinant Mouse Cd300a, Fc tagged	HEK293	Fc	Met 1-Arg 183	Inquiry
Mouse	CD300A-1809MCL	Recombinant Mouse CD300A cell lysate	Human Cell	Non		Inquiry
Mouse	Cd300a-126M	Recombinant Mouse Cd300a Protein, His (Fc)-Avi-tagged	HEK293	His&Fc&Avi		Inquiry
Mouse	Cd300a-2760M	Recombinant Mouse Cd300a Protein, His&GST-tagged	E.coli	His&GST	Gly39-Gln284	Inquiry
Mouse	Cd300a-126M-B	Recombinant Mouse Cd300a Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Rhesus monkey	CD300A-1692R	Recombinant Rhesus Monkey CD300A Protein	HEK293	Non		Inquiry
Rhesus monkey	CD300A-1693R	Recombinant Rhesus Monkey CD300A Protein, hIgG1-tagged	HEK293	Fc		Inquiry
Rhesus monkey	CD300A-1694R	Recombinant Rhesus Monkey CD300A Protein, hIgG4-tagged	HEK293	hIgG4		Inquiry
Leu18-Gln178	CD300A-1443C	Recombinant Cynomolgus CD300A protein, His-tagged	C-His		Leu18-Gln178	Inquiry
Rattus norvegicus (Rat)	RFL1490RF	Recombinant Full Length Rat Cmrf35-Like Molecule 8(Cd300A) Protein, His-Tagged	E.coli expression system	His	Full Length of Mature Protein (27-310)	Inquiry
Chicken	CD300A-3355C	Recombinant Chicken CD300A	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
Other Resource

CD300A involved in several pathways and played different roles in them. We selected most pathways CD300A participated on our site, such as Adaptive Immune System, Immune System, Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell, which may be useful for your reference. Also, other proteins which involved in the same pathway with CD300A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Adaptive Immune System	BTLA;WWP1;CTSL2;KIF2B;RBCK1;CD300LH;CHUK;DCTN6;IGLC2
Immune System	CTSLL;KIF15;TRIM45;RNF144B;RAP1GAP2B;POLR3G;GBP2;LRR1;SPSB1
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell	CD300LD;TREM1;SIGLEC11;CD200R3;CD226;CLEC2B;TREML2;CD300LF;LILRB4

CD300A has several biochemical functions, for example, phosphatidylethanolamine binding, phosphatidylserine binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CD300A itself. We selected most functions CD300A had, and list some proteins which have the same functions with CD300A. You can find most of the proteins on our site.

Function	Related Protein
phosphatidylethanolamine binding	ANXA11;LC3;CD300A;PEMT;PEBP1;MFGE8;NF1;ESYT2
phosphatidylserine binding	SCIN;CPNE6;PLCD1;AP1S2;MFGE8;CPNE1;ANXA13;RPE65;GAP43
protein binding	NPLOC4;NKG7;PML;CCDC24;ZHX1;ZSCAN21;KRTAP10-11;PIK3R2;GALR1
signaling receptor activity	OLFR78;OR51E2;CD300A

CD300A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CD300A here. Most of them are supplied by our site. Hope this information will be useful for your research of CD300A.

KRT38

Research Area

Macrophage Markers

Monocyte Markers

CD Antigen (Neutrophils)

Dendritic Cell Co-stimulatory Molecules

Dendritic Cell ITIM/ITAM Immunoreceptors

Co-stimulatory Molecules

ITIM/ITAM Immunoreceptors and Related Molecules

Chakrabarti, S; Multani, S; et al. Whole genome expression profiling in chewing-tobacco-associated oral cancers: a pilot study. MEDICAL ONCOLOGY 32:-(2015).

Jiang, L; Zhou, JX; et al. The Stimulatory Role of CD300a in Diffuse Large B-Cell Lymphoma. BLOOD 124:-(2014).