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Recombinant Human CD300A protein, Fc-tagged

Cat.No. : CD300A-267H
Product Overview : Recombinant Human CD300A (Leu18-Gln178) protein was fused to human IgG1 Fc tag at C-terminus and expressed in human 293 cells (HEK293).
  • Specification
  • Gene Information
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Description : CD300 antigen-like family member A (CD300A) is also known as CMRF35-like molecule 8 (CLM-8), CMRF-35-H9, CMRF35-H, Immunoglobulin superfamily member 12 (IGSF12), NK inhibitory receptor, LMIR1, which belongs to the CD300 family. CD300A contains one Ig-like V-type (immunoglobulin-like) domain. CD300A is expressed not only by natural killer (NK) cells but also by T-cell subsets, B-cells, dendritic cells, mast cells, granulocytes and monocytes. CD300A is a inhibitory receptor which may contribute to the down-regulation of cytolytic activity in natural killer (NK) cells, and to the down-regulation of mast cell degranulation.
Source : HEK293
Species : Human
Tag : human IgG1 Fc
Predicted N Terminal : Leu18
Form : Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 100 mM Glycine, pH7.5, 10% trehalose.
Molecular Mass : The protein has a calculated MW of 44 kDa. As a result of glycosylation, the protein migrates as 52-66 kDa under reducing (R) condition, and 105-130 kDa under non-reducing (NR) condition (SDS-PAGE).
Protein length : Leu18-Gln178
Endotoxin : Less than 1.0 EU per μg by the LAL method.
Purity : >95% as determined by SDS-PAGE.
Storage : For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20 to -70 centigrade for 12 months in lyophilized state;
-70 centigrade for 3 months under sterile conditions after reconstitution.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents.
Gene Name : CD300A
Official Symbol : CD300A
Synonyms : CD300A; CD300a molecule; CD300a antigen; CMRF35-like molecule 8; CMRF 35 H9; CMRF35H; IGSF12; IRC1; IRC2; Irp60; NK inhibitory receptor; leukocyte membrane antigen; inhibitory receptor protein 60; CD300 antigen-like family member A; immunoglobulin superfamily member 12; CMRF35H leukocyte immunoglobulin-like receptor; CLM-8; IRp60; CMRF-35H; CMRF35-H; CMRF35H9; CMRF35-H9; IRC1/IRC2; CMRF-35-H9
Gene ID : 11314
mRNA Refseq : NM_001256841
Protein Refseq : NP_001243770
MIM : 606790
UniProt ID : Q9UGN4

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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