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CDK5RAP3

  • Official Full Name

    CDK5 regulatory subunit associated protein 3

  • Overview

    CDK5 regulatory subunit-associated protein 3 (Cdk5rap3) is a recently described regulator for Cdk5 activity through interaction with CDK5R1. It may also have a role in cell proliferation. Recent studies have shown Cdk5rap3 to have a crucial role in regulating apoptosis induced by genotoxic stress by interacting with the G2/M DNA damage checkpoint. Expression of Cdk5rap3 is considered ubiquitous, and has been observed in brain, heart, kidney, liver, lung, pancreas, placenta, and skeletal muscle.
  • Synonyms

    CDK5RAP3; CDK5 regulatory subunit associated protein 3; CDK5 regulatory subunit-associated protein 3; C53; FLJ13660; HSF 27; IC53; ischemic heart CDK5 activator binding protein C53; LXXLL/leucine zipper containing ARFbinding protein; LZAP; MST016; OK/SW cl.114; ischemic heart CDK5 activator-binding protein C53; LXXLL/leucine-zipper-containing ARFbinding protein; HSF-27; OK/SW-cl.114;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CDK5RAP3-50H Recombinant Human CDK5RAP3, His-tagged E.coli His
Human CDK5RAP3-62H Recombinant Human CDK5RAP3, His-tagged HEK293 His
Human CDK5RAP3-1027H Recombinant Human CDK5RAP3 Protein, GST-Tagged Wheat Germ GST
Human CDK5RAP3-7623HCL Recombinant Human CDK5RAP3 293 Cell Lysate HEK293 N/A
Human CDK5RAP3-4787H Recombinant Human CDK5RAP3 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human CDK5RAP3-3128HF Recombinant Full Length Human CDK5RAP3 Protein, GST-tagged In Vitro Cell Free System GST 506 amino acids
Mouse Cdk5rap3-2090M Recombinant Mouse Cdk5rap3 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rat CDK5RAP3-1308R Recombinant Rat CDK5RAP3 Protein Mammalian Cell His
Rat CDK5RAP3-966R Recombinant Rat CDK5RAP3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat CDK5RAP3-966R-B Recombinant Rat CDK5RAP3 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque CDK5RAP3-787R Recombinant Rhesus monkey CDK5RAP3 Protein, His-tagged Mammalian Cell His
Rhesus Macaque CDK5RAP3-613R Recombinant Rhesus Macaque CDK5RAP3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque CDK5RAP3-613R-B Recombinant Rhesus Macaque CDK5RAP3 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish CDK5RAP3-335Z Recombinant Zebrafish CDK5RAP3 Mammalian Cell His
Chicken CDK5RAP3-3227C Recombinant Chicken CDK5RAP3 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • CDK5RAP3 Related Articles

CDK5RAP3 involved in several pathways and played different roles in them. We selected most pathways CDK5RAP3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with CDK5RAP3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

CDK5RAP3 has several biochemical functions, for example, MDM2/MDM4 family protein binding, NF-kappaB binding, cyclin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CDK5RAP3 itself. We selected most functions CDK5RAP3 had, and list some proteins which have the same functions with CDK5RAP3. You can find most of the proteins on our site.

Function Related Protein
MDM2/MDM4 family protein bindingPPARA;CDK5RAP3;PSME3;RFWD3;CDKN2A;CAV1;TRP53
NF-kappaB bindingFAF1;CDK5RAP3;MTDH;CDKN2A;HIF1AN;RELA;NPM1;CPNE1;NFKBIA
cyclin bindingMDFIC;FBXW7;CDK5RAP3;USP2;INCA1;CDK12;CDK4;CDK6;CUL3
mitogen-activated protein kinase bindingARRB2;PLCB4;SIRT1;TPR;ATF7;GTF2I;PTPRJ;MICALCL;MAPKAPK2
protein bindingTHAP11;GFER;COL13A1;SMAD3B;MEI4;ARF4;KCNH7;SNRPF;WBP4
protein kinase bindingTBL2;GRB2;PRKAG1;TCF7L2;MAP2K3;GATA6;CDKN2C;LCK;CD3E
ubiquitin-like protein ligase bindingDDRGK1;CEBPB;USP13;TRIP4;CDK5RAP3;VCP

CDK5RAP3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CDK5RAP3 here. Most of them are supplied by our site. Hope this information will be useful for your research of CDK5RAP3.

FKBP6; TSPYL4; RELA; Ufl1; 51492850; hin1l_human; 567160; BANF1; SMNDC1; UFL1; IGKC; IGHA1

Xie, P; Wei, FY; et al. Quantitative PCR Measurement of tRNA 2-Methylthio Modification for Assessing Type 2 Diabetes Risk. CLINICAL CHEMISTRY 59:1604-1612(2013).
Lee, WC; Kan, D; et al. Suppression of Extensive Neurofilament Phosphorylation Rescues alpha-Internexin/Peripherin-Overexpressing PC12 Cells from Neuronal Cell Death. PLOS ONE 7:-(2012).
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