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Official Full Name CDK5 regulatory subunit associated protein 3
Background CDK5 regulatory subunit-associated protein 3 (Cdk5rap3) is a recently described regulator for Cdk5 activity through interaction with CDK5R1. It may also have a role in cell proliferation. Recent studies have shown Cdk5rap3 to have a crucial role in regulating apoptosis induced by genotoxic stress by interacting with the G2/M DNA damage checkpoint. Expression of Cdk5rap3 is considered ubiquitous, and has been observed in brain, heart, kidney, liver, lung, pancreas, placenta, and skeletal muscle.
Synonyms CDK5RAP3; CDK5 regulatory subunit associated protein 3; CDK5 regulatory subunit-associated protein 3; C53; FLJ13660; HSF 27; IC53; ischemic heart CDK5 activator binding protein C53; LXXLL/leucine zipper containing ARFbinding protein; LZAP; MST016; OK/SW cl.114; ischemic heart CDK5 activator-binding protein C53; LXXLL/leucine-zipper-containing ARFbinding protein; HSF-27; OK/SW-cl.114
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • Myc/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CDK5RAP3-1027H Recombinant Human CDK5RAP3 Protein, GST-Tagged Wheat Germ GST
    Human CDK5RAP3-4787H Recombinant Human CDK5RAP3 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human CDK5RAP3-50H Recombinant Human CDK5RAP3, His-tagged E.coli His
    Human CDK5RAP3-62H Recombinant Human CDK5RAP3, His-tagged HEK293 His
    Human CDK5RAP3-7623HCL Recombinant Human CDK5RAP3 293 Cell Lysate HEK293 N/A
    Mouse Cdk5rap3-2090M Recombinant Mouse Cdk5rap3 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Rat CDK5RAP3-1308R Recombinant Rat CDK5RAP3 Protein Mammalian Cell His
    Rhesus Macaque CDK5RAP3-787R Recombinant Rhesus monkey CDK5RAP3 Protein, His-tagged Mammalian Cell His
    Chicken CDK5RAP3-3227C Recombinant Chicken CDK5RAP3 Mammalian Cell His
    Zebrafish CDK5RAP3-335Z Recombinant Zebrafish CDK5RAP3 Mammalian Cell His

    cdk5rap3 involved in several pathways and played different roles in them. We selected most pathways cdk5rap3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with cdk5rap3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    cdk5rap3 has several biochemical functions, for example, MDM2/MDM4 family protein binding, NF-kappaB binding, cyclin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by cdk5rap3 itself. We selected most functions cdk5rap3 had, and list some proteins which have the same functions with cdk5rap3. You can find most of the proteins on our site.

    Function Related Protein
    MDM2/MDM4 family protein binding CDKN2A; CDK5RAP3; PPARA; TRP53; CAV1; RFWD3; PSME3
    NF-kappaB binding NFKBIA; EP300; RELA; HSPA6; TAF4B; FOXP3; GSK3B; HDAC3; ANXA4; FAF1
    cyclin binding CDK4; INCA1; HDAC3; CDK13; PFTK1; CDK5RAP3; FBXW7; CDK2; CDKN1A; CDK14
    mitogen-activated protein kinase binding NBR1; GTF2I; MAPK7; PLCB4; MAPKAPK2; CDK5RAP3; TPR; ACE; ARRB2; SIRT1
    protein binding SPA17; GEMIN4; PAGE2; ALDH3A1; ALS2CR11; NRBP1; EFEMP1; LY6H; RNF180; ETV6
    protein kinase binding PRC1; CSPG4; HIF1A; CCNB3; PTPN6; CADPS; CD4; PRKAG1; MVP; PARN
    ubiquitin-like protein ligase binding VCP; USP13; CEBPB; CDK5RAP3; TRIP4; DDRGK1

    cdk5rap3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with cdk5rap3 here. Most of them are supplied by our site. Hope this information will be useful for your research of cdk5rap3.

    FKBP6; TSPYL4; RELA; Ufl1; 51492850; hin1l_human; 567160; BANF1; SMNDC1; UFL1; IGKC; IGHA1

    Xie, P; Wei, FY; et al. Quantitative PCR Measurement of tRNA 2-Methylthio Modification for Assessing Type 2 Diabetes Risk. CLINICAL CHEMISTRY 59:1604-1612(2013).
    Lee, WC; Kan, D; et al. Suppression of Extensive Neurofilament Phosphorylation Rescues alpha-Internexin/Peripherin-Overexpressing PC12 Cells from Neuronal Cell Death. PLOS ONE 7:-(2012).

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