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CHL1

  • Official Full Name

    cell adhesion molecule with homology to L1CAM

  • Overview

    The protein encoded by this gene is a member of the L1 gene family of neural cell adhesion molecules. It is a neural recognition molecule that may be involved in signal transduction pathways. The deletion of one copy of this gene may be responsible for m
  • Synonyms

    CHL1; cell adhesion molecule with homology to L1CAM; neural cell adhesion molecule L1-like protein; CALL; Cell adhesion molecule with homology to L1CAM (close homolog of L1); Cell adhesion molecule with homology to L1CAM (close homologue of L1); Close homolog of L1; FLJ44930; L1 cell adhesion molecule 2; L1CAM2; MGC132578; Neural cell adhesion molecule; chl1-like protein; LICAM2; AI465420; A530023M13Rik;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Antibody
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • E.coli
  • HEK293
  • Human Cell
  • Mammalian cells
  • Mouse
  • Wheat Germ
  • GST
  • hFc
  • His
  • His (Fc)
  • Avi
  • His|T7
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CHL1-3145H Recombinant Human CHL1 protein, His-tagged HEK293 His Met1-Gln1080
Human CHL1-1244H Recombinant Human CHL1 Protein, GST-Tagged Wheat Germ GST
Human CHL1-2202HCL Recombinant Human CHL1 cell lysate Human Cell N/A
Human CAB11511MH Mouse Anti-Human Cell Adhesion Molecule With Homology to L1CAM Monoclonal Antibody Mouse N/A
Human CHL1-1527H Recombinant Human CHL1 protein, His & T7-tagged E.coli His/T7 Pro35~Glu328 (Accession # O00533)
Human CHL1-3833H Recombinant Human CHL1 protein, His-tagged E.coli His 737-1066 aa
Human CHL1-1703H Recombinant Human CHL1 Protein (Pro35-Glu328), N-His tagged E.coli N-His Pro35-Glu328
Mouse Chl1-455M Active Recombinant Mouse Chl1, His-tagged Mammalian cells His
Mouse Chl1-489M Recombinant Mouse Chl1 Human Cell N/A Met1-Gln1027
Mouse CHL1-220M Recombinant Mouse Chl1, Fc tagged Human Cell His
Mouse CHL1-260M Recombinant Mouse Chl1, His tagged Human Cell His
Mouse CHL1-001MCL Recombinant Mouse CHL1 cell lysate Human Cell N/A
Mouse Chl1-1646M Recombinant Mouse Chl1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Chl1-1646M-B Recombinant Mouse Chl1 Protein Pre-coupled Magnetic Beads HEK293
Mouse CHL1-1975M Recombinant Mouse CHL1 protein, hFc-tagged HEK293 hFc Met1-Gln1027
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • CHL1 Related Articles

CHL1 involved in several pathways and played different roles in them. We selected most pathways CHL1 participated on our site, such as Axon guidance, CHL1 interactions, Developmental Biology, which may be useful for your reference. Also, other proteins which involved in the same pathway with CHL1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Axon guidanceDPYSL5A;UNC5A;GNAI3;ABL1;PPP3CC;RGMA;ROBO1;EFNA1A;SCN2B
CHL1 interactionsCNTN6;CHL1
Developmental BiologySCN2A;MEF2B;CAP1;EFNB2A;SPTBN2;LGI1;MED8;CEBPB;NR6A1
L1CAM interactionsEZRA;SCN2A;CD24;NRP2;RANBP9;KCNQ2;SCN3B;SCN2B;CHL1

CHL1 has several biochemical functions, for example, protease binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CHL1 itself. We selected most functions CHL1 had, and list some proteins which have the same functions with CHL1. You can find most of the proteins on our site.

Function Related Protein
protease bindingTIMP2A;TIMP2;CRADD;SELL;CAST;CHL1;ELANE;RYR1;Serpina1c

CHL1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CHL1 here. Most of them are supplied by our site. Hope this information will be useful for your research of CHL1.

JUN; E2F1

Katic, J; Loers, G; et al. Interaction of the Cell Adhesion Molecule CHL1 with Vitronectin, Integrins, and the Plasminogen Activator Inhibitor-2 Promotes CHL1-Induced Neurite Outgrowth and Neuronal Migration. JOURNAL OF NEUROSCIENCE 34:14606-14623(2014).
Marko, NF; Coughlan, C; et al. Towards an integrated molecular and clinical strategy to predict early recurrence in surgically resected non-functional pituitary adenomas. JOURNAL OF CLINICAL NEUROSCIENCE 19:1535-1540(2012).
  • Q&As
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