clec1b

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clec1b

Official Full Name C-type lectin domain family 1, member b
Background Natural killer (NK) cells express multiple calcium-dependent (C-type) lectin-like receptors, such as CD94 (KLRD1; MIM;602894) and NKG2D (KLRC4; MIM 602893), that interact with major histocompatibility complex class I molecules and;either inhibit or activate cytotoxicity and cytokine secretion. CLEC2 is a C-type lectin-like receptor expressed in;myeloid cells and NK cells (Colonna et al., 2000 (PubMed 10671229)).
Synonyms CLEC1B; C-type lectin domain family 1, member b; C-type lectin domain family 1 member B; 1810061I13Rik; C type lectin domain family 1 member B; C type lectin like receptor 2; C-type lectin-like receptor 2; C-type lectin-like receptor-2; CLC1B_HUMAN; CLEC 2; CLEC 2B; CLEC-2; CLEC2; CLEC2B; PRO1384; QDED721; OTTMUSP00000033486; OTTMUSP00000033487
    • Species :
    • Human
    • Mouse
    • Rhesus Macaque
    • Source :
    • E.coli
    • HEK293
    • Human Cell
    • Insect Cell
    • Mammalian Cell
    • NS0
    • Rabbit
    • Wheat Germ
    • Tag :
    • Fc
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CAB11514RH Rabbit Anti-Human C-type Lectin Domain Family 1, Member B Monoclonal Antibody Rabbit N/A
    Human CLEC1B-11311H Recombinant Human CLEC1B, GST-tagged E.coli GST
    Human CLEC1B-1460H Recombinant Human CLEC1B Protein, GST-tagged Wheat Germ GST
    Human CLEC1B-1773HCL Recombinant Human CLEC1B cell lysate Human Cell N/A
    Human CLEC1B-23H Recombinant Human CLEC1B protein, His-tagged Insect Cell His
    Human CLEC1B-279H Recombinant Human CLEC1B, His-tagged NS0 His
    Human CLEC1B-6911H Recombinant Human CLEC1B, His tagged Human Cell His
    Mouse CLEC1B-3552M Recombinant Mouse CLEC1B Protein Mammalian Cell His
    Mouse Clec1b-858M Recombinant Mouse Clec1b Protein, Fc-tagged HEK293 Fc
    Rhesus Macaque CLEC1B-904R Recombinant Rhesus monkey CLEC1B Protein, His-tagged Mammalian Cell His

    clec1b involved in several pathways and played different roles in them. We selected most pathways clec1b participated on our site, such as GPVI-mediated activation cascade, Hemostasis, Platelet activation, signaling and aggregation, which may be useful for your reference. Also, other proteins which involved in the same pathway with clec1b were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    GPVI-mediated activation cascade PDPN; PIK3R6; RHOB; CLEC1B; FCER1GL; LCP2A; RHOGA; C6orf25; G6b
    Hemostasis TRPC6A; LOC100514666; KIF4A; F13A1B; GATA2A; CD84; NFE2; CXADR; HBB-Y; MGC173646
    Platelet activation, signaling and aggregation CALU; WDR1; SRGN; SCG3; TRPC6A; CLEC1B; STXBP3; MMRN1; CAP1; CD9B

    clec1b has several biochemical functions, for example, carbohydrate binding, protein binding, transmembrane signaling receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by clec1b itself. We selected most functions clec1b had, and list some proteins which have the same functions with clec1b. You can find most of the proteins on our site.

    Function Related Protein
    carbohydrate binding CALR; CLEC7A; KLRC3; PRG2; GALNT9; ILLR1; KLRB1A; LGALSL; CLEC4A; GALNT12
    protein binding NXF2; SCYL1; FES; SIN3A; TMEM173; MSH6; SGCA; MC1R; MIS18A; BTK
    transmembrane signaling receptor activity GPR126; CD72; FZD7A; GPR124; GHRHR2; CR2; ERBB3; CD27; OR4D6; FZD7B

    clec1b has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with clec1b here. Most of them are supplied by our site. Hope this information will be useful for your research of clec1b.

    NINL

    Cui, J; Chen, YJ; et al. Mechanisms and pathways of innate immune activation and regulation in health and cancer. HUMAN VACCINES & IMMUNOTHERAPEUTICS 10:3270-3285(2014).
    Noack, S; Seiffart, V; et al. Periostin Secreted by Mesenchymal Stem Cells Supports Tendon Formation in an Ectopic Mouse Model. STEM CELLS AND DEVELOPMENT 23:1844-1857(2014).

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