CLEC2B

Official Full Name

C-type lectin domain family 2, member B
Overview

This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type 2 transmembrane protein may function as a cell activation antigen. An alternative splice variant has been described but its full-length sequence has not been determined. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region.
Synonyms

CLEC2B; C-type lectin domain family 2, member B; C type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 2 (activation induced) , CLECSF2; C-type lectin domain family 2 member B; AICL; HP10085; Activation induced C type lectin; C type lectin domain family 2 member B; C type lectin superfamily member 2; CLEC2; CLECSF2; IFN alpha2b inducing related protein 1; IFNRG1; activation-induced C-type lectin; C-type lectin superfamily member 2; IFN-alpha2b-inducing related protein 1; IFN-alpha-2b-inducing-related protein 1; C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 2 (activation-induced);

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Human
Rhesus Macaque

Source

E.coli
HEK293
In Vitro Cell Free System
Insect Cell
Mammalian Cell
Wheat Germ

Tag

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	CLEC2B-1462H	Recombinant Human CLEC2B Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	CLEC2B-7120H	Recombinant Human CLEC2B, His-tagged	E.coli	His	26-149aa	Inquiry
Human	CLEC2B-454H	Recombinant Human CLEC2B Protein, Fc-tagged	HEK293	Fc	Lys26-His149	Inquiry
Human	CLEC2B-7452HCL	Recombinant Human CLEC2B 293 Cell Lysate	HEK293	Non		Inquiry
Human	CLEC2B-001H	Recombinant Human CLEC2B Protein, hIgG-His-tagged	Insect Cell	His&Fc	26-149	$799 / 50µg
Human	CLEC2B-2132HF	Recombinant Full Length Human CLEC2B Protein, GST-tagged	In Vitro Cell Free System	GST	149 amino acids	Inquiry
Rhesus Macaque	CLEC2B-905R	Recombinant Rhesus monkey CLEC2B Protein, His-tagged	Mammalian Cell	His		Inquiry
Rhesus Macaque	CLEC2B-730R-B	Recombinant Rhesus Macaque CLEC2B Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Rhesus Macaque	CLEC2B-730R	Recombinant Rhesus Macaque CLEC2B Protein, His (Fc)-Avi-tagged	HEK293	His&Fc&Avi		Inquiry

Involved Pathway
Protein Function
Interacting Protein

CLEC2B involved in several pathways and played different roles in them. We selected most pathways CLEC2B participated on our site, such as Adaptive Immune System, Immune System, Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell, which may be useful for your reference. Also, other proteins which involved in the same pathway with CLEC2B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Adaptive Immune System	CDKN1A;UBE2V2;LRSAM1;MGC174155;CTSO;DYNC1I2;CD300LB;DCTN2;AGO3
Immune System	CLEC2G;AP1G1;TNIP2;IRF9;IRF2;ASB7;ATP6V1G3;TCIRG1;ACTR1A
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell	CD200;SIGLEC8;LAIR1;CD300A;CD200R2;KLRG1;CD300LD;CD300E;KIR2DS2

CLEC2B has several biochemical functions, for example, carbohydrate binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CLEC2B itself. We selected most functions CLEC2B had, and list some proteins which have the same functions with CLEC2B. You can find most of the proteins on our site.

Function	Related Protein
carbohydrate binding	LGALS9L1;CHODL;SIGLEC6;GALNT1;PRPS2;GALNT3;PKD1;PYGB;LGALS2B

CLEC2B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CLEC2B here. Most of them are supplied by our site. Hope this information will be useful for your research of CLEC2B.