Recombinant Human CLEC2B Protein, hIgG-His-tagged

• Cat.No.: CLEC2B-001H
• Product Overview: Recombinant human CLEC2B protein (26-149aa), fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Specification

• Description: CLEC2B, also known as C-type lectin domain family 2 member B, is a type-2 transmembrane member of the C-type lectin-like receptor (CTLR) family. They play diverse functions, such as cell adhesion, cell-cell signaling, glycoprotein turnover, and roles in inflammation and immune response. This protein may function as a cell activation antigen. It has variant roles such as activating receptor that triggers TNF production, NK cell mediated lysis and interactions between activated and resting NK cells.
• Source: Insect cell
• Species: Human
• Tag: hIgG-His
• Form: Liquid
• Molecular Mass: 41.7 kDa
• AASequence: ADPKLTRDSQSLCPYDWIGFQNKCY YFSKEEGDWNSSKYNCSTQHADLTI IDNIEEMNFLRRYKCSSDHWIGLKM AKNRTGQWVDGATFTKSFGMRGSEG CAYLSDDGAATARCYTERKWICRKR IHLEPKSCDKTHTCPPCPAPELLGG PSVFLFPPKPKDTLMISRTPEVTCV VVDVSHEDPEVKFNWYVDGVEVHNA KTKPREEQYNSTYRVVSVLTVLHQD WLNGKEYKCKVSNKALPAPIEKTIS KAKGQPREPQVYTLPPSRDELTKNQ VSLTCLVKGFYPSDIAVEWESNGQP ENNYKTTPPVLDSDGSFFLYSKLTV DKSRWQQGNVFSCSVMHEALHNHYT QKSLSLSPGKHHHHHH
• N-terminal Sequence Analysis: Ala
• Endotoxin: < 1.0 EU per 1 μg of protein (determined by LAL method)
• Purity: > 90% by SDS - PAGE
• Storage: Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles.
• Concentration: 0.25 mg/mL (determined by Absorbance at 280nm)
• Storage Buffer: In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol.
• Warning: For research use only. This product is not intended or approved for human, diagnostics or veterin

Gene Information

• Gene Name: CLEC2B C-type lectin domain family 2 member B [ Homo sapiens (human) ]
• Official Symbol: CLEC2B
• Synonyms: CLEC2B; C-type lectin domain family 2 member B; AICL; IFNRG1; CLECSF2; HP10085; C-type lectin domain family 2 member B; C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 2 (activation-induced); C-type lectin superfamily member 2; IFN-alpha-2b-inducing-related protein 1; IFN-alpha2b-inducing related protein 1; activation-induced C-type lectin
• Gene ID: 9976
• mRNA Refseq: NM_005127
• Protein Refseq: NP_005118
• MIM: 603242
• UniProt ID: Q92478