CLK2 Protein


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Official Full Name CDC-like kinase 2
Background This gene encodes a member of the CLK family of dual specificity protein kinases. CLK family members have been shown to interact with, and phosphorylate, serine- and arginine-rich (SR) proteins of the spliceosomal complex, which is a part of the regulatory mechanism that enables the SR proteins to control RNA splicing. Note that this gene is distinct from TELO2 gene (GeneID:9894), which shares CLK2 and hCLK2 symbol aliases in common with this gene, but encodes a protein that is involved in telomere length regulation. [provided by RefSeq, Jul 2008]
Synonyms CLK2; CDC-like kinase 2; hCLK2; dual specificity protein kinase CLK2; CLK kinase;
    • Species :
    • Chicken
    • Human
    • Source :
    • E.coli
    • HEK293
    • Insect Cell
    • Mammalian Cell
    • Sf9 Insect Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • His-B2M
    • His-SUMO
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CLK2-2703H Recombinant Human CLK2 protein, His-SUMO-tagged E.coli His-SUMO
    Human CLK2-2704H Recombinant Human CLK2 protein, His-B2M-tagged E.coli His-B2M
    Human CLK2-1005H Recombinant Human CDC-Like Kinase 2, GST-tagged Sf9 Insect Cell GST
    Human CLK2-11334H Recombinant Human CLK2, GST-tagged E.coli GST
    Human CLK2-1493H Recombinant Human CLK2 Protein, GST-tagged Insect Cell GST
    Human CLK2-1494H Recombinant Human CLK2 Protein, GST-tagged Wheat Germ GST
    Human CLK2-285H Recombinant Human CDC-like Kinase 2, GST-tagged, Active Sf9 Insect Cell GST
    Human CLK2-7440HCL Recombinant Human CLK2 293 Cell Lysate HEK293 N/A
    Chicken CLK2-2980C Recombinant Chicken CLK2 Mammalian Cell His
    Kit-1572 CLK2 Kinase Binding Assay Kit N/A

    CLK2 involved in several pathways and played different roles in them. We selected most pathways CLK2 participated on our site, such as mRNA processing, which may be useful for your reference. Also, other proteins which involved in the same pathway with CLK2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    CLK2 has several biochemical functions, for example, ATP binding, protein binding, protein serine/threonine kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CLK2 itself. We selected most functions CLK2 had, and list some proteins which have the same functions with CLK2. You can find most of the proteins on our site.

    Function Related Protein
    ATP binding KTI12; NOL9; KIF25; NAGK; ABCG5; DDX4; CASKA; HK3; MYH10; TTLL10
    protein binding GABARAP; GAP43; TMEM231; ELMO3; DCBLD2; HOXA3; KLF4; ANKRD32; KCTD15; DSTN
    protein serine/threonine kinase activity MKNK1; SGK2B; AKT2L; ALPK2; KALRN; RIOK3; ERN2; MAPK14A; VRK2; TESK1
    protein serine/threonine/tyrosine kinase activity DYRK4; DYRK1AA; TNK2; AURKB; SGK1; AKT1; CLK3; RPS6KB1; DYRK1B; TTK
    protein tyrosine kinase activity LTK; PTK7A; JAK2A; FGFR1A; MAP2K6; NTRK2B; TYK2; PTK6B; FGFR1OP; ERBB3B

    CLK2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CLK2 here. Most of them are supplied by our site. Hope this information will be useful for your research of CLK2.


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