|Official Full Name||coatomer protein complex, subunit epsilon|
|Background||The product of this gene is an epsilon subunit of coatomer protein complex. Coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles. It is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. Coatomer complex consists of at least the alpha, beta, beta, gamma, delta, epsilon and zeta subunits. Alternatively spliced transcript variants encoding different isoforms have been identified.|
|Synonyms||COPE; coatomer protein complex, subunit epsilon; coatomer subunit epsilon; epsilon COP; 1110005D17Rik; Coatomer epsilon subunit; Coatomer protein complex subunit epsilon; Cope1; Epsilon coat protein; Epsilon COP I; Epsilon subunit of coatomer protein complex; FLJ13241; epsilon-coat protein; epsilon-COP|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
cope involved in several pathways and played different roles in them. We selected most pathways cope participated on our site, such as COPI Mediated Transport, Golgi to ER Retrograde Transport, Membrane Trafficking, which may be useful for your reference. Also, other proteins which involved in the same pathway with cope were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|COPI Mediated Transport||ARCN1A; COPZ1; ARCN1B; COPB1; TERFA; ARCN1; COPE; ARF1; COPG; COPB2|
|Golgi to ER Retrograde Transport||ARCN1A; COPZ1; TERFA; COPE; COPB1; COPB2; ARCN1; COPG; ARCN1B|
|Membrane Trafficking||NSFA; EXOC1; COPG; TRAPPC4; FTH1B; DAB2; CLINT1; RAB10; TFR1B; TFG|
|Vesicle-mediated transport||TFR1B; NFX1; TGOLN2; SCGB3A2; FTH1A; BLOC1S6; BLOC1S4; AP1S3A; PICALMB; SNAPIN|
cope has several biochemical functions, for example, protein binding, structural molecule activity. Some of the functions are cooperated with other proteins, some of the functions could acted by cope itself. We selected most functions cope had, and list some proteins which have the same functions with cope. You can find most of the proteins on our site.
|protein binding||SFRP5; TA; LAGE3; PDGFA; KPNB1; RFFL; KCNB1; LCE1B; MID1IP1; PIK3R3|
|structural molecule activity||CLDNB; CLDN4; SPRR2H; CRCT1; MAP7D2A; MPZ; CLDN15LA; IFFO2; COPB1; LMNB1|
cope has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with cope here. Most of them are supplied by our site. Hope this information will be useful for your research of cope.
EFHC2; Copa; CASP4; COPA; malF2; TSG101; pi3p; 15-deoxy-delta(12,14; midostaurin; Katna1; XRCC3; FN1; MYH6; LRRK2; NUDCD1; Erp44