Recombinant Human COPE, GST-tagged

• Cat.No.: COPE-11456H
• Product Overview: Recombinant Human COPE protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Description: The product of this gene is an epsilon subunit of coatomer protein complex. Coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles. It is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. Coatomer complex consists of at least the alpha, beta, beta, gamma, delta, epsilon and zeta subunits. Alternatively spliced transcript variants encoding different isoforms have been identified.
• Source: E.coli
• Species: Human
• Tag: GST
• Protein length: 1-308a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: COPE coatomer protein complex, subunit epsilon [ Homo sapiens ]
• Official Symbol: COPE
• Synonyms: COPE; coatomer protein complex, subunit epsilon; coatomer subunit epsilon; epsilon COP; epsilon coat protein; epsilon-coat protein; coatomer epsilon subunit; epsilon-COP; FLJ13241
• Gene ID: 11316
• mRNA Refseq: NM_007263
• Protein Refseq: NP_009194
• MIM: 606942
• UniProt ID: O14579
• Chromosome Location: 19p13.11
• Pathway: COPI Mediated Transport, organism-specific biosystem; Golgi to ER Retrograde Transport, organism-specific biosystem; Membrane Trafficking, organism-specific biosystem
• Function: binding; structural molecule activity