COX11

  • Official Full Name

    COX11 cytochrome c oxidase assembly homolog (yeast)

  • Overview

    Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein which is not a structural subunit, but may be a heme A biosynthetic enzyme involved in COX formation, according to the yeast mutant studies. However, the studies in Rhodobacter sphaeroides suggest that this gene is not required for heme A biosynthesis, but required for stable formation of the Cu(B) and magnesium centers of COX. This human protein is predicted to contain a transmembrane domain localized in the mitochondrial inner membrane. Multiple transcript variants encoding different isoforms have been found for this gene. A related pseudogene has been found on chromosome 6.

  • Synonyms

    COX11;COX11 cytochrome c oxidase assembly homolog (yeast);COX11 (yeast) homolog, cytochrome c oxidase assembly protein;cytochrome c oxidase assembly protein COX11, mitochondrial;COX11P;cytochrome c oxidase assembly protein COX11;cytochrome c oxidase subunit 11;COX11 homolog;COX11 homolog, cytochrome c oxidase assembly protein (yeast);COX11 homolog, cytochrome c oxidase assembly protein

Recombinant Proteins

  • Human
  • Mouse
  • Zebrafish
  • Rhesus macaque
  • Pongo Abelii
  • Arabidopsis thaliana
  • Wheat Germ
  • Mammalian Cells
  • HEK293
  • In Vitro Cell Free System
  • E.coli
  • GST
  • His
  • Non
  • Avi
  • Fc
Cat.# Product name Source (Host) Species Tag Protein Length Price
COX11-1734H Recombinant Human COX11 Protein, GST-tagged Wheat Germ Human GST
COX11-3807M Recombinant Mouse COX11 Protein Mammalian Cells Mouse His
COX11-5315Z Recombinant Zebrafish COX11 Mammalian Cells Zebrafish His
COX11-981R Recombinant Rhesus monkey COX11 Protein, His-tagged Mammalian Cells Rhesus macaque His
COX11-7337HCL Recombinant Human COX11 293 Cell Lysate HEK293 Human Non
COX11-1908M Recombinant Mouse COX11 Protein, His (Fc)-Avi-tagged HEK293 Mouse Avi&Fc&His
COX11-1908M-B Recombinant Mouse COX11 Protein Pre-coupled Magnetic Beads HEK293 Mouse
COX11-1993HF Recombinant Full Length Human COX11 Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 276 amino acids
COX11-806R Recombinant Rhesus Macaque COX11 Protein, His (Fc)-Avi-tagged HEK293 Rhesus macaque Avi&Fc&His
COX11-806R-B Recombinant Rhesus Macaque COX11 Protein Pre-coupled Magnetic Beads HEK293 Rhesus macaque
RFL25127PF Recombinant Full Length Pongo Abelii Cytochrome C Oxidase Assembly Protein Cox11, Mitochondrial(Cox11) Protein, His-Tagged E.coli Pongo Abelii His Full L. Full Length of Mature Protein (29-277)
RFL27536AF Recombinant Full Length Arabidopsis Thaliana Cytochrome C Oxidase Assembly Protein Cox11, Mitochondrial(Cox11) Protein, His-Tagged E.coli Arabidopsis thaliana His Full L. Full Length (81-287)

    Involved Pathway

    COX11 involved in several pathways and played different roles in them. We selected most pathways COX11 participated on our site, such as Electron Transport Chain,Gene Expression,Generic Transcription Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with COX11 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Generic Transcription Pathway ZNF256,ZNF230,COX8A,ZNF596,ZNF480,ZIM2,NR1D2,VDRB,TRIM28,ZNF189
    Metabolic pathways ATP6V1BA,PIGM,INPP5J,PKMA,PNLIPRP2,DGUOK,LASS5,PNAT10,PFKM,NDUFA4L2
    Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. NDUFAF2,TACO1,NDUFAF3,NDUFAF6,NDUFAF7,UCP3,COX18,NDUFAF5,ATP5S,ETFA
    Electron Transport Chain COX6A1,ATP5S,COX6C,SLC25A14,ATP5H,COX7A2,NDUFS7,COX5B,COX17,ATPIF1
    Respiratory electron transport SCO1,LRPPRC,NDUFAF5,SURF1,NDUFAF6,NDUFA11,ETFA,NDUFAF2,COX18,COX14
    Gene Expression ZNF143A,TXNL4A,MED16,SUDS3,ZNF41,SKILB,QTRTD1,NR2E1,ZNF287,ZNF549
    Oxidative phosphorylation ATP6V0CB,NDUFB10,ATP6V0CA,NDUFB2,COX5B2,ATP6V1B2,NDUFA9,ATP6V0E,MT-ND1,LHPP
    Metabolism COX18,FAAH2A,SLC25A13,SLC25A14,SLC5A9,DUT,SLC27A5,SLC25A27,ACY3.2,ACOT12

    Protein Function

    COX11 has several biochemical functions, for example, copper ion binding,cytochrome-c oxidase activity,electron carrier activity. Some of the functions are cooperated with other proteins, some of the functions could acted by COX11 itself. We selected most functions COX11 had, and list some proteins which have the same functions with COX11. You can find most of the proteins on our site.

    Function Related Protein
    copper ion binding F5,TP53,MT3,COMMD1,HIST2H3A,AOC1,HAMP,CUTC,ADNP,HEPHL1A
    electron carrier activity ACOX3,ACADS,GLRX2,FDX1B,IDH3B,LOXL2,IVD,ACOXL,P4HA2,CIAPIN1
    cytochrome-c oxidase activity COX6A2,COX4I1,COX7A2A,CYB5A,COX5B,COX8C,COX6A1,COX7A2,COX6C,COX5B2

    Interacting Protein

    COX11 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with COX11 here. Most of them are supplied by our site. Hope this information will be useful for your research of COX11.

    SQSTM1;RPL19;Csk;Smn1;Cep44;Kctd5;Bag2;COA3

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