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Recombinant Full Length Human COX11 Protein, GST-tagged

Cat.No. : COX11-1993HF
Product Overview : Human COX11 full-length ORF ( NP_004366.1, 1 a.a. - 276 a.a.) recombinant protein with GST-tag at N-terminal.
  • Specification
  • Gene Information
  • Related Products
Description : Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein which is not a structural subunit, but may be a heme A biosynthetic enzyme involved in COX formation, according to the yeast mutant studies. However, the studies in Rhodobacter sphaeroides suggest that this gene is not required for heme A biosynthesis, but required for stable formation of the Cu(B) and magnesium centers of COX. This human protein is predicted to contain a transmembrane domain localized in the mitochondrial inner membrane. Multiple transcript variants encoding different isoforms have been found for this gene. A related pseudogene has been found on chromosome 6. [provided by RefSeq, Jun 2009]
Source : In Vitro Cell Free System
Species : Human
Tag : GST
Molecular Mass : 57.8 kDa
Protein Length : 276 amino acids
AA Sequence : MGGLWRPGWRCVPFCGWRWIHPGSP TRAAERVEPFLRPEWSGTGGAERGL RWLGTWKRCSLRARHPALQPPRRPK SSNPFTRAQEEERRRQNKTTLTYVA AVAVGMLGASYAAVPLYRLYCQTTG LGGSAVAGHASDKIENMVPVKDRII KISFNADVHASLQWNFRPQQTEIYV VPGETALAFYRAKNPTDKPVIGIST YNIVPFEAGQYFNKIQCFCFEEQRL NPQEEVDMPVFFYIDPEFAEDPRMI KVDLITLSYTFFEAKEGHKLPVPGY N
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : COX11 COX11 cytochrome c oxidase assembly homolog (yeast) [ Homo sapiens ]
Official Symbol : COX11
Synonyms : COX11; COX11 cytochrome c oxidase assembly homolog (yeast); COX11 (yeast) homolog, cytochrome c oxidase assembly protein; cytochrome c oxidase assembly protein COX11, mitochondrial; COX11P; cytochrome c oxidase assembly protein COX11; cytochrome c oxidase subunit 11; COX11 homolog, cytochrome c oxidase assembly protein
Gene ID : 1353
mRNA Refseq : NM_001162861
Protein Refseq : NP_001156333
MIM : 603648
UniProt ID : Q9Y6N1

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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