cul4a Protein, cullin 4A


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Official Full Name cullin 4A
Background CUL4A is the ubiquitin ligase component of a multimeric complex involved in the degradation of DNA damage-response proteins.
Synonyms CUL4A; cullin 4A; cullin-4A; CUL-4A; OTTHUMP00000018753; OTTHUMP00000018754
    • Species :
    • Human
    • Mouse
    • Zebrafish
    • Source :
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CUL4A-2134H Recombinant Human CUL4A Protein, GST-tagged Wheat Germ GST
    Human CUL4A-2180H Recombinant Human CUL4A Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human CUL4A-7182HCL Recombinant Human CUL4A 293 Cell Lysate HEK293 N/A
    Mouse CUL4A-4078M Recombinant Mouse CUL4A Protein Mammalian Cell His
    Zebrafish CUL4A-11259Z Recombinant Zebrafish CUL4A Mammalian Cell His

    cul4a involved in several pathways and played different roles in them. We selected most pathways cul4a participated on our site, such as Nucleotide excision repair, Ubiquitin mediated proteolysis, which may be useful for your reference. Also, other proteins which involved in the same pathway with cul4a were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Nucleotide excision repair POLD1; COPS8; INO80C; RFC3; PCNA; POLE3; COPS3; MNAT1; ERCC1; YY1
    Ubiquitin mediated proteolysis NHLRC1; TCEB1B; UBE2B; MID1; UBE2W; UBE2D2L; CDC27; UBR5; NEDD4; KEAP1B

    cul4a has several biochemical functions, for example, protein binding, contributes_to ubiquitin protein ligase activity, ubiquitin protein ligase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by cul4a itself. We selected most functions cul4a had, and list some proteins which have the same functions with cul4a. You can find most of the proteins on our site.

    Function Related Protein
    protein binding GSS; CNOT10; Itga10&Itgb1; NGDN; SH3BP4; WSB1; CDKN1B; PKM; STAU2; POLR3C
    contributes_to ubiquitin protein ligase activity MED12; FBXL5; SKP2; FBXL20; CUL4A; CUL1A; UBXN6; FBXL18; FBXL14; FBXL14A
    ubiquitin protein ligase binding GSK3B; DERL1; VCL; TRAF3; USP13; MYOD1; TRIB1; XRCC5; DIO2; CUL3A

    cul4a has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with cul4a here. Most of them are supplied by our site. Hope this information will be useful for your research of cul4a.

    DDB1; CAND1; DDB2; Dtl; Ddb1; COPS5; RBBP5

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