Recombinant Full Length Human CUL4A Protein, GST-tagged

• Cat.No.: CUL4A-2399HF
• Product Overview: Human CUL4A full-length ORF ( NP_001008895.1, 1 a.a. - 759 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: CUL4A is the ubiquitin ligase component of a multimeric complex involved in the degradation of DNA damage-response proteins (Liu et al., 2009 [PubMed 19481525]).[supplied by OMIM, Oct 2009]
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 114.1 kDa
• Protein Length: 759 amino acids
• AA Sequence: MADEAPRKGSFSALVGRTNGLTKPA ALAAAPAKPGGAGGSKKLVIKNFRD RPRLPDNYTQDTWRKLHEAVRAVQS STSIRYNLEELYQAVENLCSHKVSP MLYKQLRQACEDHVQAQILPFREDS LDSVLFLKKINTCWQDHCRQMIMIR SIFLFLDRTYVLQNSTLPSIWDMGL ELFRTHIISDKMVQSKTIDGILLLI ERERSGEAVDRSLLRSLLGMLSDLQ VYKDSFELKFLEETNCLYAAEGQRL MQEREVPEYLNHVSKRLEEEGDRVI TYLDHSTQKPLIACVEKQLLGEHLT AILQKGLDHLLDENRVPDLAQMYQL FSRVRGGQQALLQHWSEYIKTFGTA IVINPEKDKDMVQDLLDFKDKVDHV IEVCFQKNERFVNLMKESFETFINK RPNKPAELIAKHVDSKLRAGNKEAT DEELERTLDKIMILFRFIHGKDVFE AFYKKDLAKRLLVGKSASVDAEKSM LSKLKHECGAAFTSKLEGMFKDMEL SKDIMVHFKQHMQNQSDSGPIDLTV NILTMGYWPTYTPMEVHLTPEMIKL QEVFKAFYLGKHSGRKLQWQTTLGH AVLKAEFKEGKKEFQVSLFQTLVLL MFNEGDGFSFEEIKMATGIEDSELR RTLQSLACGKARVLIKSPKGKEVED GDKFIFNGEFKHKLFRIKINQIQMK ETVEEQVSTTERVFQDRQYQIDAAI VRIMKMRKTLGHNLLVSELYNQLKF PVKPGDLKKRIESLIDRDYMERDKD NPNQYHYVA
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: CUL4A cullin 4A [ Homo sapiens ]
• Official Symbol: CUL4A
• Synonyms: CUL4A; cullin 4A; cullin-4A; CUL-4A
• Gene ID: 8451
• mRNA Refseq: NM_001008895
• Protein Refseq: NP_001008895
• MIM: 603137
• UniProt ID: Q13619