Cxcl5
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Official Full Name
chemokine (C-X-C motif) ligand 5
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Overview
This gene encodes a protein that is a member of the CXC subfamily of chemokines. Chemokines, which recruit and activate leukocytes, are classified by function (inflammatory or homeostatic) or by structure. This protein is proposed to bind the G-protein coupled receptor chemokine (C-X-C motif) receptor 2 to recruit neutrophils, to promote angiogenesis and to remodel connective tissues. This protein is thought to play a role in cancer cell proliferation, migration, and invasion. -
Synonyms
CXCL5; chemokine (C-X-C motif) ligand 5; SCYB5; ENA-78;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- GMP Proteins
- Bovine
- Cattle
- Cynomolgus
- Human
- Mouse
- Rat
- CHO
- E. coli
- E.coli
- HEK293
- HEK293T
- In Vitro Cell Free System
- Mammalian Cell
- Mammalian cells
- Yeast
- Biotin
- Flag
- GST
- His
- His (Fc)
- Avi
- His|GST
- Myc|DDK
- N/A
- N
- Tag Free
- Involved Pathway
- Protein Function
- Interacting Protein
- Cxcl5 Related Articles
- Cxcl5 Related Gene Family
- Cxcl5 Related Research Area
Cxcl5 involved in several pathways and played different roles in them. We selected most pathways Cxcl5 participated on our site, such as Cytokine-cytokine receptor interaction, Chemokine signaling pathway, TNF signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with Cxcl5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Cytokine-cytokine receptor interaction | IFNB1;IL6;CXCL1;CXCL6;IL20RA;LTA;GM13305;IFNA2;IL18 |
| Chemokine signaling pathway | CXCL11;MAPK1;XCL2;AKT1;ARRB1;GNAI3;CDC42;ROCK2;IKBKG |
| TNF signaling pathway | IL18R1;MLKL;MAP2K4;BAG4;MAP2K1;RPS6KA4;TNFRSF1B;CXCL2;VCAM1 |
| Pertussis | IL12A;ITGB2L;TICAM2;C2;IL-8;IL23;Il23a;C1R;CALM3 |
| Rheumatoid arthritis | ATP6V1G1;IL-8;CCL2;CXCL12;ATP6V0C;CCL3L3;ATP6V1B2;CCL3L1;HLA-DRB5 |
Cxcl5 has several biochemical functions, for example, CXCR chemokine receptor binding, chemokine activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Cxcl5 itself. We selected most functions Cxcl5 had, and list some proteins which have the same functions with Cxcl5. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| CXCR chemokine receptor binding | CXCL1;CXCL12A;CXCL18B;CXCL12;CXCL6;PPBP;CXCL20;CXCL2;CXCL3 |
| chemokine activity | IL8L2;CXCL13;CXCL12A;CXCL14;CCL1;Ccl21c;XCL2;Ccl12;CCL5 |
Cxcl5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Cxcl5 here. Most of them are supplied by our site. Hope this information will be useful for your research of Cxcl5.
- Q&As
- Reviews
Q&As (5)
Ask a questionCXCL5 is implicated in promoting tumor growth and metastasis by facilitating the migration of cancer cells and modulating the tumor microenvironment.
Several clinical trials are exploring the efficacy of drugs that modulate CXCL5 levels in various diseases, including cancer, autoimmune disorders, and inflammatory conditions.
CXCL5 has been identified as a regulator of angiogenesis, influencing the formation of new blood vessels, a process crucial for tumor growth and wound healing.
CXCL5's role in recruiting cells to damaged tissues makes it a potential candidate for enhancing regenerative medicine approaches, such as tissue repair and wound healing.
CXCL5 levels can be measured in blood or tissue samples to assess the extent of inflammation, aiding in the diagnosis and monitoring of various diseases.
Customer Reviews (3)
Write a reviewIts versatility and reliability make it an indispensable asset for scientists seeking to explore the complexities of various biological systems.
Its stability and functional attributes ensure reliable imaging and facilitate the elucidation of complex protein structures.
The CXCL5 protein is known for its exceptional quality, making it a highly suitable choice for meeting diverse experimental needs.
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