|Official Full Name||DDB1 and CUL4 associated factor 7|
|Background||Involved in craniofacial development. Acts upstream of the EDN1 pathway and is required for formation of the upper jaw equivalent, the palatoquadrate. The activity required for EDN1 pathway function differs between the first and second arches (By similarity). Associates with DIAPH1 and controls GLI1 transcriptional activity. Could be involved in normal and disease skin development. May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.|
|Synonyms||DCAF7; DDB1 and CUL4 associated factor 7; WD repeat domain 68 , WDR68; DDB1- and CUL4-associated factor 7; HAN11; human anthocyanin; seven WD repeat protein of the AN11 family 1; SWAN 1; AN11; DCAF7_HUMAN; WD repeat domain 68; WD repeat protein An11 homolog; WD repeat-containing protein 68; WD repeat-containing protein An11 homolog; WDR68; WD-repeat protein; seven-WD-repeat protein of the AN11 family-1; SWAN-1|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
dcaf7 involved in several pathways and played different roles in them. We selected most pathways dcaf7 participated on our site, such as TNF-alpha/NF-kB Signaling Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with dcaf7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|TNF-alpha/NF-kB Signaling Pathway||UNC5CL; MCC; RNF216; MARK2; PPP1R13L; SMARCB1; TIFA; NKIRAS1; ZFAND5; RNF25|
dcaf7 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by dcaf7 itself. We selected most functions dcaf7 had, and list some proteins which have the same functions with dcaf7. You can find most of the proteins on our site.
|protein binding||MED21; MED18; PSMG1; FAM82A2; TSPAN1; MT1F; PARP1; PAGE2; UGGT1; LY6H|
dcaf7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with dcaf7 here. Most of them are supplied by our site. Hope this information will be useful for your research of dcaf7.
MAP3K1; HIPK2; DYRK1A