ELOVL4
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Official Full Name
ELOVL fatty acid elongase 4
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Background
This gene encodes a membrane-bound protein which is a member of the ELO family, proteins which participate in the biosynthesis of fatty acids. Consistent with the expression of the encoded protein in photoreceptor cells of the retina, mutations and small deletions in this gene are associated with Stargardt-like macular dystrophy (STGD3) and autosomal dominant Stargardt-like macular dystrophy (ADMD), also referred to as autosomal dominant atrophic macular degeneration. -
Synonyms
ELOVL4; ELOVL fatty acid elongase 4; elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast) like 4 , STGD2, STGD3; elongation of very long chain fatty acids protein 4; cancer/testis antigen 118; CT118; 3-keto acyl-CoA synthase ELOVL4; ADMD; Elongation of very long chain fatty acids (FEN1/Elo2 SUR4/Elo3 yeast) like 4; elongation of very long chain fatty acids (FEN1/Elo2 SUR4/Elo3 yeast)-like 4; Elongation of very long chain fatty acids like 4; ELOV L4; ELOV4_HUMAN; ELOVL 4; FLJ17667; FLJ92876; Stargardt disease 3; Stargardt disease 3 autosomal dominant; STGD 2; STGD 3; STGD2; STGD3; Stargardt disease 3 (autosomal dominant); elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 4;
- Involved Pathway
- Protein Function
- Interacting Protein
- ELOVL4 Related Articles
ELOVL4 involved in several pathways and played different roles in them. We selected most pathways ELOVL4 participated on our site, such as Fatty acid elongation, which may be useful for your reference. Also, other proteins which involved in the same pathway with ELOVL4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Fatty acid elongation | ELOVL3;HSD17B12B;ELOVL4B;ACOT5;ELOVL4A;HADH;ELOVL7;ELOVL7A;PTPLA |
ELOVL4 has several biochemical functions, for example, transferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ELOVL4 itself. We selected most functions ELOVL4 had, and list some proteins which have the same functions with ELOVL4. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| transferase activity | SULT2ST3;UGT1B2;CAMK1DA;CAMK1GB;B3GNT8;EHMT1B;MGAT1B;VPRBP;NTRK3A |
ELOVL4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ELOVL4 here. Most of them are supplied by our site. Hope this information will be useful for your research of ELOVL4.
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