ELOVL4

  • Official Full Name

    ELOVL fatty acid elongase 4

  • Background

    This gene encodes a membrane-bound protein which is a member of the ELO family, proteins which participate in the biosynthesis of fatty acids. Consistent with the expression of the encoded protein in photoreceptor cells of the retina, mutations and small deletions in this gene are associated with Stargardt-like macular dystrophy (STGD3) and autosomal dominant Stargardt-like macular dystrophy (ADMD), also referred to as autosomal dominant atrophic macular degeneration.
  • Synonyms

    ELOVL4; ELOVL fatty acid elongase 4; elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast) like 4 , STGD2, STGD3; elongation of very long chain fatty acids protein 4; cancer/testis antigen 118; CT118; 3-keto acyl-CoA synthase ELOVL4; ADMD; Elongation of very long chain fatty acids (FEN1/Elo2 SUR4/Elo3 yeast) like 4; elongation of very long chain fatty acids (FEN1/Elo2 SUR4/Elo3 yeast)-like 4; Elongation of very long chain fatty acids like 4; ELOV L4; ELOV4_HUMAN; ELOVL 4; FLJ17667; FLJ92876; Stargardt disease 3; Stargardt disease 3 autosomal dominant; STGD 2; STGD 3; STGD2; STGD3; Stargardt disease 3 (autosomal dominant); elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 4;
    • Type:
    • Recombinant Proteins
    • Protein Pre-coupled Magnetic Beads
    • Species :
    • Chicken
    • Cynomolgus Monkey
    • Human
    • Mouse
    • Rhesus Macaque
    • Source :
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • His (Fc)
    • Avi
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Chicken ELOVL4-4173C Recombinant Chicken ELOVL4 Mammalian Cell His
    Cynomolgus Monkey ELOVL4-491C Recombinant Cynomolgus ELOVL4 Protein, His-tagged Mammalian Cell His
    Cynomolgus Monkey ELOVL4-236C Recombinant Cynomolgus Monkey ELOVL4 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
    Cynomolgus Monkey ELOVL4-236C-B Recombinant Cynomolgus Monkey ELOVL4 Protein Pre-coupled Magnetic Beads HEK293
    Human ELOVL4-3262H Recombinant Human ELOVL4 Protein, GST-tagged Wheat Germ GST
    Mouse ELOVL4-2752M-B Recombinant Mouse ELOVL4 Protein Pre-coupled Magnetic Beads HEK293
    Mouse ELOVL4-2752M Recombinant Mouse ELOVL4 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
    Mouse ELOVL4-5150M Recombinant Mouse ELOVL4 Protein Mammalian Cell His
    Rhesus Macaque ELOVL4-1277R-B Recombinant Rhesus Macaque ELOVL4 Protein Pre-coupled Magnetic Beads HEK293
    Rhesus Macaque ELOVL4-1453R Recombinant Rhesus monkey ELOVL4 Protein, His-tagged Mammalian Cell His
    Rhesus Macaque ELOVL4-1277R Recombinant Rhesus Macaque ELOVL4 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
    • Involved Pathway
    • Protein Function
    • Interacting Protein
    • ELOVL4 Related Articles

    ELOVL4 involved in several pathways and played different roles in them. We selected most pathways ELOVL4 participated on our site, such as Fatty acid elongation, which may be useful for your reference. Also, other proteins which involved in the same pathway with ELOVL4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Fatty acid elongationELOVL3;HSD17B12B;ELOVL4B;ACOT5;ELOVL4A;HADH;ELOVL7;ELOVL7A;PTPLA

    ELOVL4 has several biochemical functions, for example, transferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ELOVL4 itself. We selected most functions ELOVL4 had, and list some proteins which have the same functions with ELOVL4. You can find most of the proteins on our site.

    Function Related Protein
    transferase activitySULT2ST3;UGT1B2;CAMK1DA;CAMK1GB;B3GNT8;EHMT1B;MGAT1B;VPRBP;NTRK3A

    ELOVL4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ELOVL4 here. Most of them are supplied by our site. Hope this information will be useful for your research of ELOVL4.

    Agbaga, MP; Tam, BM; et al. Mutant ELOVL4 That Causes Autosomal Dominant Stargardt-3 Macular Dystrophy Is Misrouted to Rod Outer Segment Disks. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE 55:3669-3680(2014).
    Kuny, S; Gaillard, F; et al. Inner Retina Remodeling in a Mouse Model of Stargardt-like Macular Dystrophy (STGD3). INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE 51:2248-2262(2010).
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