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FCRL4

Official Full Name

Fc receptor-like 4
Overview

This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein has four extracellular C2-type immunoglobulin domains, a transmembrane domain and a cytoplasmic domain that contains three immune-receptor tyrosine-based inhibitory motifs. This protein may play a role in the function of memory B-cells in the epithelia. Aberrations in the chromosomal region encoding this gene are associated with non-Hodgkin lymphoma and multiple myeloma.
Synonyms

FCRL4; Fc receptor-like 4; Fc receptor-like protein 4; CD307d; FCRH4; IGFP2; IRTA1; Fc receptor homolog 4; Fc receptor like 4; Fc receptor like protein 4; FcR like protein 4; IFGP family protein 2; Immune receptor translocation associated protein 1; Immunoglobulin superfamily receptor translocation associated 1; Immunoglobulin superfamily receptor translocation associated gene 1; hIFGP2; fcR-like protein 4; immunoglobulin superfamily Fc receptor, gp42; immune receptor translocation-associated protein 1;

Type

Recombinant Proteins
Cell & Tissue Lysates

Species

Human
Rhesus monkey

Source

E.coli
HEK293
Human Cells
Mamanlian cells
Yeast

Tag

Fc
Flag
hIgG4
His
SUMO
Myc
DDK
Non

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	FCRL4-12H	Recombinant Human FCRL4 protein, MYC/DDK-tagged	HEK293	Myc&DDK		Inquiry
Human	FCRL4-920H	Recombinant Human FCRL4 protein, His-tagged	HEK293	His	20-387aa	Inquiry
Human	FCRL4-6274HCL	Recombinant Human FCRL4 293 Cell Lysate	HEK293	Non		Inquiry
Human	FCRL4-1798H	Recombinant Human FCRL4 Protein (20-387 aa), His-SUMO-tagged	E.coli	His&SUMO	20-387 aa	Inquiry
Human	FCRL4-151H	Recombinant Human FCRL4 Protein, DYKDDDDK-tagged	Human Cells	Flag		Inquiry
Human	FCRL4-1843H	Recombinant Human FCRL4 Protein (20-387 aa), His-tagged	Yeast	His	20-387 aa	Inquiry
Human	FCRL4-2643HFL	Recombinant Full Length Human FCRL4 protein, Flag-tagged	Mamanlian cells	Flag		Inquiry
Rhesus monkey	FCRL4-1718R	Recombinant Rhesus Monkey FCRL4 Protein, hIgG1-tagged	HEK293	Fc	20-395	Inquiry
Rhesus monkey	FCRL4-1719R	Recombinant Rhesus Monkey FCRL4 Protein, hIgG4-tagged	HEK293	hIgG4	20-395	Inquiry

Involved Pathway
Protein Function
Interacting Protein
Other Resource

FCRL4 involved in several pathways and played different roles in them. We selected most pathways FCRL4 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with FCRL4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

FCRL4 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FCRL4 itself. We selected most functions FCRL4 had, and list some proteins which have the same functions with FCRL4. You can find most of the proteins on our site.

Function	Related Protein
protein binding	MRPL28;SID4;CRABP1;STK39;WDR24;TRAIP;CDCP1;EIF4EA;RAD51L3

FCRL4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FCRL4 here. Most of them are supplied by our site. Hope this information will be useful for your research of FCRL4.

TFF1; TFF2

Research Area

B Cell Receptor-Associated Proteins

Fc Receptors

ITIM/ITAM Immunoreceptors and Related Molecules

Amu, S; Lavy-Shahaf, G; et al. Frequency and phenotype of B cell subpopulations in young and aged HIV-1 infected patients receiving ART. RETROVIROLOGY 11:-(2014).

Ben Mkaddem, S; Christou, I; et al. IgA, IgA Receptors, and Their Anti-inflammatory Properties. FC RECEPTORS 382:221-235(2014).