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FCRL5

  • Official Full Name

    Fc receptor-like 5

  • Overview

    Fc receptor homologs (FcRH5), also known as IRTA2 proteins, are transmembrane proteins with sequence homology to classical Fc receptor families. FcRH5 function as activating or inhibitory receptors on discrete B cell populations and are involved in B-cell development and differentiation in peripheral lymphoid organs. FcRH5 expression is deregulated in multiple myeloma and Burkitt lymphoma cell lines with 1q21 abnormalities. FcRH5 may play a critical role for the pathogenesis of B-cell lymphoma.
  • Synonyms

    FCRL5; Fc receptor-like 5; Fc receptor-like protein 5; BXMAS1; CD307e; FCRH5; IRTA2; fcR-like protein 5; fc receptor homolog 5; immune receptor translocation-associated protein 2; immunoglobulin superfamily receptor translocation associated 2 (IRTA2); CD307; PRO820; FLJ00333; FLJ00397; RP11-217A12.1; MGC119590; MGC119592; MGC119593; DKFZp667F216; DKFZp667E2019;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rhesus monkey
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • GST
  • hIgG1
  • hIgG4
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human FCRL5-506H Active Recombinant Human Fc Receptor-Like 5, His-tagged Mammalian cells His
Human FCRL5-379H Active Recombinant Human FCRL5, His-tagged Mammalian cells His
Human FCRL5-12831H Recombinant Human FCRL5, His-tagged E.coli His C-term-150a.a.
Human FCRL5-4011H Recombinant Human FCRL5 Protein, GST-tagged Wheat Germ GST
Human FCRL5-4010H Recombinant Human FCRL5 Protein Wheat Germ N/A
Human FCRL5-971H Recombinant Human FCRL5 protein, His-Avi-tagged HEK293 His-Avi Glu16-Gly851
Human FCRL5-2940H-B Recombinant Human FCRL5 Protein Pre-coupled Magnetic Beads HEK293
Human FCRL5-4769HF Recombinant Full Length Human FCRL5 Protein In Vitro Cell Free System 437 amino acids
Human FCRL5-971HB Active Recombinant Human FCRL5 protein, His-Avi-tagged, Biotinylated HEK293 His-Avi Gln 16 - Gly 851
Human FCRL5-4770HF Recombinant Full Length Human FCRL5 Protein, GST-tagged In Vitro Cell Free System GST 977 amino acids
Human FCRL5-2940H Recombinant Human FCRL5 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Fcrl5-503M Active Recombinant Mouse Fc receptor-like 5, His-tagged Mammalian cells His
Mouse FCRL5-5798M Recombinant Mouse FCRL5 Protein Mammalian Cell His
Mouse Fcrl5-3196M Recombinant Mouse Fcrl5 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Fcrl5-3196M-B Recombinant Mouse Fcrl5 Protein Pre-coupled Magnetic Beads HEK293
Rhesus monkey FCRL5-1707R Recombinant Rhesus Monkey FCRL5 Protein, hIgG1-tagged HEK293 hIgG1
Rhesus monkey FCRL5-1706R Recombinant Rhesus Monkey FCRL5 Protein HEK293 N/A
Rhesus monkey FCRL5-1708R Recombinant Rhesus Monkey FCRL5 Protein, hIgG4-tagged HEK293 hIgG4
  • FCRL5 Related Articles
  • FCRL5 Related Research Area

FCRL5 involved in several pathways and played different roles in them. We selected most pathways FCRL5 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with FCRL5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

FCRL5 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by FCRL5 itself. We selected most functions FCRL5 had, and list some proteins which have the same functions with FCRL5. You can find most of the proteins on our site.

Function Related Protein

FCRL5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FCRL5 here. Most of them are supplied by our site. Hope this information will be useful for your research of FCRL5.

Franco, A; Damdinsuren, B; et al. Human Fc Receptor-Like 5 Binds Intact IgG via Mechanisms Distinct from Those of Fc Receptors. JOURNAL OF IMMUNOLOGY 190:5739-5746(2013).
Elkins, K; Zheng, B; et al. FcRL5 as a Target of Antibody-Drug Conjugates for the Treatment of Multiple Myeloma. MOLECULAR CANCER THERAPEUTICS 11:2222-2232(2012).
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