FDFT1
-
Official Full Name
farnesyl-diphosphate farnesyltransferase 1
-
Overview
This gene encodes a membrane-associated enzyme located at a branch point in the mevalonate pathway. The encoded protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene. -
Synonyms
FDFT1; farnesyl-diphosphate farnesyltransferase 1; squalene synthase; squalene synthetase; FPP:FPP farnesyltransferase; presqualene-di-diphosphate synthase; SS; SQS; DGPT; ERG9;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Bos taurus (Bovine)
- Chicken
- Homo sapiens (Human)
- Human
- Mouse
- Mus musculus (Mouse)
- Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
- Rat
- Rhesus Macaque
- Zebrafish
- E.coli
- E.coli expression system
- HEK293
- HEK293T
- In Vitro Cell Free System
- Mammalian Cell
- Mammalian cells
- Wheat Germ
- Flag
- GST
- His
- His (Fc)
- Avi
- Myc
- DDK
- N/A
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
---|---|---|---|---|---|---|
Human | FDFT1-27574TH | Recombinant Human FDFT1 | Wheat Germ | N/A | 417 amino acids | |
Human | FDFT1-1829H | Recombinant Human FDFT1 protein, His-tagged | E.coli | His | His269~His417 (Accession # P37268) | |
Human | FDFT1-6271HCL | Recombinant Human FDFT1 293 Cell Lysate | HEK293 | N/A | ||
Human | FDFT1-3282H | Recombinant Human FDFT1 Protein (His269-His417), His tagged | E.coli | His | His269-His417 | |
Human | FDFT1-4025H | Recombinant Human FDFT1 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Myc/DDK | ||
Human | FDFT1-4057H | Recombinant Human FDFT1 Protein, GST-tagged | Wheat Germ | GST | ||
Human | FDFT1-2894H | Recombinant Human FDFT1 protein, His-tagged | E.coli | His | 2-417aa | |
Human | FDFT1-167HF | Recombinant Full Length Human FDFT1 Protein | In Vitro Cell Free System | 417 amino acids | ||
Human | FDFT1-4774HF | Recombinant Full Length Human FDFT1 Protein, GST-tagged | In Vitro Cell Free System | GST | 417 amino acids | |
Human | FDFT1-1048HFL | Recombinant Full Length Human FDFT1 Protein, C-Flag-tagged | Mammalian cells | Flag | ||
Human | FDFT1-904H-B | Recombinant Human FDFT1 Protein Pre-coupled Magnetic Beads | HEK293 | |||
Human | FDFT1-904H | Recombinant Human FDFT1 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Mouse | FDFT1-5803M | Recombinant Mouse FDFT1 Protein | Mammalian Cell | His | ||
Mouse | Fdft1-1830M | Recombinant Mouse Fdft1 protein, His-tagged | E.coli | His | Ile217~His416 (Accession # P53798) | |
Mouse | FDFT1-3201M-B | Recombinant Mouse FDFT1 Protein Pre-coupled Magnetic Beads | HEK293 | |||
Mouse | FDFT1-3201M | Recombinant Mouse FDFT1 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Mouse | Fdft1-2980M | Recombinant Mouse Fdft1 Protein, Myc/DDK-tagged | HEK293T | Myc/DDK | ||
Rat | FDFT1-2308R | Recombinant Rat FDFT1 Protein | Mammalian Cell | His | ||
Rat | Fdft1-1831R | Recombinant Rat Fdft1 protein, His-tagged | E.coli | His | Phe187~His416 (Accession # Q02769) | |
Rat | FDFT1-1965R | Recombinant Rat FDFT1 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Rat | FDFT1-1965R-B | Recombinant Rat FDFT1 Protein Pre-coupled Magnetic Beads | HEK293 | |||
Bos taurus (Bovine) | RFL4907BF | Recombinant Full Length Bovine Squalene Synthase(Fdft1) Protein, His-Tagged | E.coli expression system | His | Full Length (1-417) | |
Homo sapiens (Human) | RFL13592HF | Recombinant Full Length Human Squalene Synthase(Fdft1) Protein, His-Tagged | E.coli expression system | His | Full Length (1-417) | |
Mus musculus (Mouse) | RFL12338MF | Recombinant Full Length Mouse Squalene Synthase(Fdft1) Protein, His-Tagged | E.coli expression system | His | Full Length (1-416) | |
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) | RFL1110PF | Recombinant Full Length Pongo Abelii Squalene Synthase(Fdft1) Protein, His-Tagged | E.coli expression system | His | Full Length (1-417) | |
Rhesus Macaque | FDFT1-1683R | Recombinant Rhesus monkey FDFT1 Protein, His-tagged | Mammalian Cell | His | ||
Rhesus Macaque | FDFT1-1505R | Recombinant Rhesus Macaque FDFT1 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Rhesus Macaque | FDFT1-1505R-B | Recombinant Rhesus Macaque FDFT1 Protein Pre-coupled Magnetic Beads | HEK293 | |||
Zebrafish | FDFT1-7996Z | Recombinant Zebrafish FDFT1 | Mammalian Cell | His | ||
Chicken | FDFT1-3354C | Recombinant Chicken FDFT1 | Mammalian Cell | His |
- Involved Pathway
- Protein Function
- Interacting Protein
FDFT1 involved in several pathways and played different roles in them. We selected most pathways FDFT1 participated on our site, such as Steroid biosynthesis, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with FDFT1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
---|---|
Steroid biosynthesis | CYP2R1;LIPA;HSD17B7;SOAT2;DHCR24;CEL.1;CELL;SQLE;SC5D |
Metabolic pathways | AK9;ATP5G3;HYKK;CDS2;TCIRG1;DCT;HMGCRA;MTR;LDHBA |
FDFT1 has several biochemical functions, for example, farnesyl-diphosphate farnesyltransferase activity, oxidoreductase activity, squalene synthase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by FDFT1 itself. We selected most functions FDFT1 had, and list some proteins which have the same functions with FDFT1. You can find most of the proteins on our site.
Function | Related Protein |
---|---|
farnesyl-diphosphate farnesyltransferase activity | |
oxidoreductase activity | ALDH2.2;ADH1;CYP2AA7;AKR1B7;CYP2D26;VAT1;DHRS13L1;CYP2A12;F8 |
squalene synthase activity |
FDFT1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FDFT1 here. Most of them are supplied by our site. Hope this information will be useful for your research of FDFT1.
PSTPIP1; SMNDC1; C1orf168; RUVBL1; ANXA5; ITGB5; SHPRH; ARL6IP1; TMEM43; RUVBL2; 15-deoxy-delta(12,14; FN1; 1C; HDAC10
- Q&As
- Reviews
Q&As (0)
Ask a questionAsk a Question for All FDFT1 Products
Required fields are marked with *
My Review for All FDFT1 Products
Required fields are marked with *