Recombinant Human FDFT1 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: FDFT1-4025H
• Product Overview: FDFT1 MS Standard C13 and N15-labeled recombinant protein (NP_004453) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a membrane-associated enzyme located at a branch point in the mevalonate pathway. The encoded protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 48.1 kDa
• AA Sequence: MEFVKCLGHPEEFYNLVRFRIGGKR KVMPKMDQDSLSSSLKTCYRYLNQT SRSFAAVIQALDGEMRNAVCIFYLV LRALDTLEDDMTISVEKKVPLLHNF HSFLYQPDWRFMESKEKDRQVLEDF PTISLEFRNLAEKYQTVIADICRRM GIGMAEFLDKHVTSEQEWDKYCHYV AGLVGIGLSRLFSASEFEDPLVGED TERANSMGLFLQKTNIIRDYLEDQQ GGREFWPQEVWSRYVKKLGDFAKPE NIDLAVQCLNELITNALHHIPDVIT YLSRLRNQSVFNFCAIPQVMAIATL AACYNNQQVFKGAVKIRKGQAVTLM MDATNMPAVKAIIYQYMEEIYHRIP DSDPSSSKTRQIISTIRTQNLPNCQ LISRSHYSPIYLSFVMLLAALSWQY LTTLSQVTEDYVQTGEHTRTRPLEQ KLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: FDFT1 farnesyl-diphosphate farnesyltransferase 1 [ Homo sapiens (human) ]
• Official Symbol: FDFT1
• Synonyms: FDFT1; farnesyl-diphosphate farnesyltransferase 1; squalene synthase; squalene synthetase; FPP:FPP farnesyltransferase; presqualene-di-diphosphate synthase; SS; SQS; DGPT; ERG9
• Gene ID: 2222
• mRNA Refseq: NM_004462
• Protein Refseq: NP_004453
• MIM: 184420
• UniProt ID: P37268