FGF11

  • Official Full Name

    fibroblast growth factor 11

  • Overview

    The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. The function of this gene has not yet been determined. The expression pattern of the mouse homolog implies a role in nervous system development.

  • Synonyms

    FGF11;fibroblast growth factor 11;FHF3;fibroblast growth factor homologous factor 3;FLJ16061;MGC45269;MGC102953;FGF 11;FGF-11;FGF11_HUMAN;FHF 3;FHF-3;OTTHUMP00000135275

Recombinant Proteins

  • Mouse
  • Human
  • Mammalian Cells
  • E.coli
  • HEK293
  • Wheat Germ
  • His
  • T7
  • Avi
  • Fc
  • GST

    Involved Pathway

    FGF11 involved in several pathways and played different roles in them. We selected most pathways FGF11 participated on our site, such as MAPK signaling pathway,Ras signaling pathway,Rap signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with FGF11 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Rap signaling pathway GRIN2B,SIPA1L1,PDGFB,FGF20,F2R,PRKCG,APBB1IP,NRAS,VEGFC,PRKD3
    Ras signaling pathway GRIN2A,RALBP1,ANGPT2,PLCG2,FGF21,PIK3CA,NRAS,RAB5B,RASSF1,PLA2G6
    Regulation of Actin Cytoskeleton RHOAD,PDGFAB,PIK3R3A,FGF11A,GNG12,RRAS,FGF3,PPP1R12A,PIKFYVE,GNA12A
    PIK-Akt signaling pathway FGF10,ITGB1,Gh,AKT2,IFNA4,TLR2,GYS2,ITGA2B,LPAR6,GRB2
    Melanoma BRAF,NRAS,HGF,MITF,FGF16,FGF4,PIK3R3,PDGFD,FGF9,FGF13
    Pathways in cancer RB1,FH,MMP1A,PIK3CG,TRAF2,IKBKB,DAPK1,FZD1,ARAF,LAMB3
    MAPK signaling pathway CACNA1D,MKNK2A,CACNA2D2,RAP1A,MAPK10,TAOK1,ELK1,MAPK13,PPM1AB,FGF10

    Protein Function

    FGF11 has several biochemical functions, for example, growth factor activity,receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FGF11 itself. We selected most functions FGF11 had, and list some proteins which have the same functions with FGF11. You can find most of the proteins on our site.

    Function Related Protein
    growth factor activity CSF1A,MDKB,NDR2,LACRT,CTGF,NDP,PDGFC,TGFB2,NUDT6,GDF6B
    receptor binding NPFFL,SERPINE1,HAO2,RSPO3,PVRL3B,F2RL1,ACOX3,TESPA1,CADM1B,DAO

    Interacting Protein

    FGF11 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FGF11 here. Most of them are supplied by our site. Hope this information will be useful for your research of FGF11.

    FGF11 Related Signal Pathway

    Resources

    Gene Families

    Growth Factors

    Research Area

    FGF Family
    FGF Ligands
    Fibroblast Growth Factor (FGF)

    References

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