FGF11
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Official Full Name
fibroblast growth factor 11 -
Overview
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. The function of this gene has not yet been determined. The expression pattern of the mouse homolog implies a role in nervous system development. -
Synonyms
FGF11;fibroblast growth factor 11;FHF3;fibroblast growth factor homologous factor 3;FLJ16061;MGC45269;MGC102953;FGF 11;FGF-11;FGF11_HUMAN;FHF 3;FHF-3;OTTHUMP00000135275
Recombinant Proteins
- Mouse
- Human
- Mammalian Cells
- E.coli
- HEK293
- Wheat Germ
- His
- T7
- Avi
- Fc
- GST
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| FGF11-5839M | Recombinant Mouse FGF11 Protein | Mammalian Cells | Mouse | His |
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| FGF11-8154H | Recombinant Human FGF11 protein, His & T7-tagged | E.coli | Human | His&T7 | Leu44~His212 |
|
| FGF11-025H | Recombinant Human FGF11 Protein | E.coli | Human | 5-103 a.a. |
|
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| FGF11-103H | Active Recombinant Human FGF11 Protein (Met1-Pro225), C-His tagged, Animal-free, Carrier-free | E.coli | Human | His | Met1-Pro225 |
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| FGF11-104H | Active Recombinant Human FGF11 Protein (Pro64-Pro225), C-His tagged, Animal-free, Carrier-free | E.coli | Human | His | Pro64-Pro225 |
|
| FGF11-3226M | Recombinant Mouse FGF11 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | Avi&Fc&His |
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| FGF11-3226M-B | Recombinant Mouse FGF11 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| FGF11-4101H | Recombinant Human FGF11 Protein, GST-tagged | Wheat Germ | Human | GST |
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Involved Pathway
FGF11 involved in several pathways and played different roles in them. We selected most pathways FGF11 participated on our site, such as MAPK signaling pathway,Ras signaling pathway,Rap signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with FGF11 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Melanoma | FGF1,MAPK3,FGF10,Pdgfa&Pdgfb,FGF20,PDGFRA,HGF,PIK3R5,PIK3R3,NRAS |
| Rap signaling pathway | MAGI2,APBB1IP,PRKCZ,Itgam&Itgb2,GNAO1,GNAI2,LPAR2,PRKD3,ITGB3,VAV2 |
| MAPK signaling pathway | AKT2L,STMN1B,HSPA1A,HSPA2,PPP3CCB,TAB2,PLA2G4A,PRKACAB,FAS,CACNG6 |
| Regulation of Actin Cytoskeleton | RAF1,CDC42L,EZR,EZRB,PPP1CB,ARHGEF7A,GNA12A,ARPC4L,BAIAP2A,ARHGEF7 |
| Pathways in cancer | FZD1,RAC1,PLCB3,NTRK1,WNT16,WNT8B,RASSF5,FGF19,MAPK1,Fzd4 |
| Ras signaling pathway | FGF14,RASGRP3,GNG3,CSF1,FGF7,RAPGEF5,FGF18,PIK3CD,GNG7,GNB4 |
| PIK-Akt signaling pathway | PPP2R5C,IFNA14,COL6A4,PKN2,LAMB4,FGF19,IL2RA,HRAS,LPAR6,PDGFRB |
Protein Function
FGF11 has several biochemical functions, for example, growth factor activity,receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FGF11 itself. We selected most functions FGF11 had, and list some proteins which have the same functions with FGF11. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| receptor binding | CXCL1,F2,Artn,NPPB,TYROBP,LTA,CLCF1,HAO1,LAMA1,EDN3 |
| growth factor activity | GMFB,CLEC11A,REG1A,Pdgfa&Pdgfb,FGF22,IGF2B,BMP10,FGF13B,FGF6,MSTN |
Interacting Protein
FGF11 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FGF11 here. Most of them are supplied by our site. Hope this information will be useful for your research of FGF11.
FGF11 Related Signal Pathway
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References
