FGF17

  • Official Full Name

    fibroblast growth factor 17

  • Overview

    The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes including embryonic development cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was shown to be prominently expressed in the cerebellum and cortex. The mouse homolog of this gene was localized to specific sites in the midline structures of the forebrain, the midbrain-hindbrain junction, developing skeleton and developing arteries, which suggests a role in central nervous system, bone and vascular development.This gene was referred to as FGF-13 in reference 2, however, its amino acid sequence and chromosomal localization are identical to FGF17.
  • Synonyms

    FGF17; fibroblast growth factor 17; FGF 13; FGF13; FGF-17; OTTHUMP00000122553; OTTHUMP00000224730; FGF-13;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • Human Cell
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • C
  • His
  • GST
  • His (Fc)
  • Avi
  • His(N
  • ter)
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human FGF17-12866H Recombinant Human FGF17, GST-tagged E.coli GST C-term-77a.a.
Human FGF17-8552H Recombinant Human FGF17 protein(Thr23-Thr216) E.coli N/A Thr23-Thr216
Human FGF17-170H Recombinant Human FGF17 protein E.coli N/A 195
Human FGF17-577H Recombinant Human fibroblast growth factor 17, His-tagged E.coli His
Human FGF17-6245HCL Recombinant Human FGF17 293 Cell Lysate HEK293 N/A
Human FGF17-1481H Recombinant Human FGF17 Protein, His-tagged E.coli N-His Thr23-Gly199
Human FGF17-309H Active Recombinant Human FGF17 Protein (Thr23-Thr216), N-His tagged, Animal-free, Carrier-free E.coli N-His Thr23-Thr216
Human FGF17-4106H Recombinant Human FGF17 Protein, GST-tagged Wheat Germ GST
Human FGF17-156H Recombinant Human FGF17 Protein, His-tagged Human Cell His
Human FGF17-3223H Recombinant Human FGF17 Protein (Thr23-Thr216), C-His tagged Mammalian cells C-His Thr23-Thr216
Human FGF17-030H Active Recombinant Human FGF17 Protein E.coli
Human FGF17-3224H Recombinant Human FGF17 Protein (Thr23-Gly199), His tagged E.coli His Thr23-Gly199
Human FGF17-4815HF Recombinant Full Length Human FGF17 Protein, GST-tagged In Vitro Cell Free System GST 239 amino acids
Human FGF17-74H Recombinant Active Human FGF17 Protein, His-tagged(N-ter) E.coli His(N-ter)
Mouse FGF17-5845M Recombinant Mouse FGF17 Protein Mammalian Cell His
Mouse Fgf17-8333M Recombinant Mouse Fgf17 protein E.coli N/A 194
Mouse FGF17-3231M Recombinant Mouse FGF17 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Fgf17-5667M Recombinant Mouse Fgf17 Protein (Thr23-Thr216), C-His tagged E.coli C-His Thr23-Thr216
Mouse FGF17-3231M-B Recombinant Mouse FGF17 Protein Pre-coupled Magnetic Beads HEK293
Rat FGF17-2329R Recombinant Rat FGF17 Protein Mammalian Cell His
Rat FGF17-1986R-B Recombinant Rat FGF17 Protein Pre-coupled Magnetic Beads HEK293
Rat FGF17-1986R Recombinant Rat FGF17 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque FGF17-1697R Recombinant Rhesus monkey FGF17 Protein, His-tagged Mammalian Cell His
Rhesus Macaque FGF17-1519R Recombinant Rhesus Macaque FGF17 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque FGF17-1519R-B Recombinant Rhesus Macaque FGF17 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish FGF17-12818Z Recombinant Zebrafish FGF17 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource
  • FGF17 Related Signal Pathway

FGF17 involved in several pathways and played different roles in them. We selected most pathways FGF17 participated on our site, such as MAPK signaling pathway, Ras signaling pathway, Rap signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with FGF17 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
MAPK signaling pathwayKCNA3;RPS6KA6;MAP2K2;GNG12A;ELK4;FGF7;PRKCBA;RAF1;PDGFB
Ras signaling pathwayPIK3R1;RASA3;GNG8;RAPGEF5;RAC2;VEGFC;FGF9;RAF1;NGFR
Rap signaling pathwayLCP2;FGF19;Pdgfa&Pdgfb;ITGA2B;GRIN2B;IGF1R;BCAR1;FGF14;FGF7
PIK-Akt signaling pathwayPDGFA;LPAR2;TEK;EIF4E2;PPP2CB;PRL;CCNE1;LAMC2;PPP2R3A
Regulation of actin cytoskeletonRRAS;MYH10;DIAPH1;LIMK1;TMSB4Y;ARPC5A;PDGFRA;IQGAP2;ROCK2B
Pathways in cancerBAD;PIK3R3;STAT5B;IGF1R;FIGF;LEF1;SMAD4;APPL1;CASP8
MelanomaFGF10;PDGFB;ARAF;TP53;Pdgfa&Pdgfb;FGF22;FGF4;MAP2K2;FGF14

FGF17 has several biochemical functions, for example, growth factor activity, type 1 fibroblast growth factor receptor binding, type 2 fibroblast growth factor receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FGF17 itself. We selected most functions FGF17 had, and list some proteins which have the same functions with FGF17. You can find most of the proteins on our site.

Function Related Protein
growth factor activityFGF9;FGF17;FGF7;INHBA;GDF1;BMP4;NOV;PPBP;OSM
type 1 fibroblast growth factor receptor bindingNPTN;FGF17;FGF18;FGF8
type 2 fibroblast growth factor receptor bindingFGF10;FGF17;FGF8;FGF18;FGF7

FGF17 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FGF17 here. Most of them are supplied by our site. Hope this information will be useful for your research of FGF17.

Research Area

Related articles

Campo, GM; Avenoso, A; et al. Beta-arrestin-2 negatively modulates inflammation response in mouse chondrocytes induced by 4-mer hyaluronan oligosaccharide. MOLECULAR AND CELLULAR BIOCHEMISTRY 399:201-208(2015).
Bob, F; Gluhovschi, G; et al. Immunohistochemical study of tubular epithelial cells and vascular endothelial cells in glomerulonephritis. RENAL FAILURE 36:1208-1214(2014).
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