FGF17 Protein


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Official Full Name fibroblast growth factor 17
Background The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes including embryonic development cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was shown to be prominently expressed in the cerebellum and cortex. The mouse homolog of this gene was localized to specific sites in the midline structures of the forebrain, the midbrain-hindbrain junction, developing skeleton and developing arteries, which suggests a role in central nervous system, bone and vascular development.This gene was referred to as FGF-13 in reference 2, however, its amino acid sequence and chromosomal localization are identical to FGF17.
Synonyms FGF17; fibroblast growth factor 17; FGF 13; FGF13; FGF-17; OTTHUMP00000122553; OTTHUMP00000224730; FGF-13
    • Species :
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E. coli
    • E.coli
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human FGF17-030H Recombinant Human FGF17 Protein E. coli
    Human FGF17-12866H Recombinant Human FGF17, GST-tagged E.coli GST
    Human FGF17-170H Recombinant Human FGF17 protein E.coli N/A
    Human FGF17-4106H Recombinant Human FGF17 Protein, GST-tagged Wheat Germ GST
    Human FGF17-577H Recombinant Human fibroblast growth factor 17, His-tagged E.coli His
    Human FGF17-6245HCL Recombinant Human FGF17 293 Cell Lysate HEK293 N/A
    Human FGF17-8552H Recombinant Human FGF17 E.coli N/A
    Mouse FGF17-5845M Recombinant Mouse FGF17 Protein Mammalian Cell His
    Mouse Fgf17-8333M Recombinant Mouse Fgf17 protein E.coli N/A
    Rat FGF17-2329R Recombinant Rat FGF17 Protein Mammalian Cell His
    Rhesus Macaque FGF17-1697R Recombinant Rhesus monkey FGF17 Protein, His-tagged Mammalian Cell His
    Zebrafish FGF17-12818Z Recombinant Zebrafish FGF17 Mammalian Cell His

    FGF17 involved in several pathways and played different roles in them. We selected most pathways FGF17 participated on our site, such as MAPK signaling pathway, Ras signaling pathway, Rap signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with FGF17 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Ras signaling pathway GNG10; ANGPT2; PLA2G1B; NFKB1; RAC1; FGFR4; VEGFA; SHC1; FGF13; TEK
    Rap signaling pathway PIK3CA; F2RL3; ITGB1; GNAO1; MAPK13; FGF19; ITGAM; FGF13; CALM3; SRC
    PIK-Akt signaling pathway LAMB4; IKBKG; FGFR1; TSC1; TNR; VEGFC; ITGB6; IFNA13; INSR; ITGA2B
    Regulation of actin cytoskeleton ITGAE; PPP1R12A; FGF2; ITGA5; GSNB; GSN; PFN1; PIKFYVE; VCL; FGF10A
    Pathways in cancer PRKACB; CBLC; NRAS; LPAR4; PPARG; HSP90AA1; MDM2; GNAI2; HSP90AB1; PLCB3
    Melanoma MAP2K2; CCND1; CDH1; HGF; FGF20; Fgf15; FGF18; FGF6; HRAS; ARAF

    FGF17 has several biochemical functions, for example, growth factor activity, type 1 fibroblast growth factor receptor binding, type 2 fibroblast growth factor receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FGF17 itself. We selected most functions FGF17 had, and list some proteins which have the same functions with FGF17. You can find most of the proteins on our site.

    Function Related Protein
    growth factor activity GPI1; INHBE; OGN; GMFG; CXCL1; TIMP1; PRL2C2; RABEP2; FGF13A; NDR1
    type 1 fibroblast growth factor receptor binding FGF8; FGF17; FGF18; NPTN
    type 2 fibroblast growth factor receptor binding FGF8; FGF17; FGF7; FGF10; FGF18

    FGF17 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FGF17 here. Most of them are supplied by our site. Hope this information will be useful for your research of FGF17.

    Campo, GM; Avenoso, A; et al. Beta-arrestin-2 negatively modulates inflammation response in mouse chondrocytes induced by 4-mer hyaluronan oligosaccharide. MOLECULAR AND CELLULAR BIOCHEMISTRY 399:201-208(2015).
    Bob, F; Gluhovschi, G; et al. Immunohistochemical study of tubular epithelial cells and vascular endothelial cells in glomerulonephritis. RENAL FAILURE 36:1208-1214(2014).

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