• Official Full Name

    fibroblast growth factor 22

  • Background

    The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. The mouse homolog of this gene was found to be preferentially expressed in the inner root sheath of the hair follicle, which suggested a role in hair development.
  • Synonyms

    FGF22; fibroblast growth factor 22; FGF-22;
    • Type:
    • Recombinant Proteins
    • Cell & Tissue Lysates
    • Protein Pre-coupled Magnetic Beads
    • Species :
    • Human
    • Mouse
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E. coli
    • E.coli
    • HEK293
    • Mammalian Cell
    • Tag :
    • Fc
    • His
    • His (Fc)
    • Avi
    • SUMO(N
    • ter)
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human FGF22-82H Recombinant Active Human FGF22 Protein, His and SUMO-tagged(N-ter) E.coli His and SUMO(N-ter)
    Human FGF22-28879TH Recombinant Human FGF22 E.coli N/A
    Human FGF22-86H Recombinant Human FGF22 Protein E.coli
    Human FGF22-32H Active Recombinant Human FGF22 protein, His-tagged E.coli His
    Human FGF22-6242HCL Recombinant Human FGF22 293 Cell Lysate HEK293 N/A
    Human FGF22-563H Recombinant Human Fibroblast Growth Factor 22 E.coli N/A
    Human FGF22-035H Recombinant Human FGF22 Protein E. coli
    Mouse FGF22-3234M Recombinant Mouse FGF22 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
    Mouse Fgf22-940M Recombinant Mouse Fgf22 protein, His-tagged E.coli His
    Mouse FGF22-3234M-B Recombinant Mouse FGF22 Protein Pre-coupled Magnetic Beads HEK293
    Mouse Fgf22-21M Recombinant Mouse Fibroblast Growth Factor 22, Fc Chimera Mammalian Cell Fc
    Mouse FGF22-5850M Recombinant Mouse FGF22 Protein Mammalian Cell His
    Rhesus Macaque FGF22-1520R-B Recombinant Rhesus Macaque FGF22 Protein Pre-coupled Magnetic Beads HEK293
    Rhesus Macaque FGF22-1520R Recombinant Rhesus Macaque FGF22 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
    Rhesus Macaque FGF22-1698R Recombinant Rhesus monkey FGF22 Protein, His-tagged Mammalian Cell His
    Zebrafish FGF22-3724Z Recombinant Zebrafish FGF22 Mammalian Cell His
    • Involved Pathway
    • Protein Function
    • Interacting Protein
    • Fgf22 Related Articles
    • Fgf22 Related Research Area
    • Fgf22 Related Signal Pathway

    Fgf22 involved in several pathways and played different roles in them. We selected most pathways Fgf22 participated on our site, such as MAPK signaling pathway, Ras signaling pathway, Rap signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with Fgf22 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    MAPK signaling pathwayPTPN7;GNG12;STK3;MAPK4;GNG12A;FGF17;NR4A1;FGFR4;MAP2K4B
    Ras signaling pathwayGNG5;RAPGEF5;FIGF;GNGT2;LOC608458;PAK1;STK4;ANGPT2;PDGFRA
    PIK-Akt signaling pathwayINS1;PPP2R5B;FGF3;FGF17;PPP2R2D;ITGA6;OSMR;PPP2R5E;COL6A4
    Regulation of actin cytoskeletonPIP5K1BA;PAK3;ROCK2B;EGFRA;PIP5K1A;MOS;ITGA3B;RHOAA;MAPK6
    Pathways in cancerITGA2B;WNT5A;ETS1;WNT7B;LAMA1;MAPK9;LAMA5;F2R;NCOA4

    Fgf22 has several biochemical functions, for example, fibroblast growth factor receptor binding, growth factor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Fgf22 itself. We selected most functions Fgf22 had, and list some proteins which have the same functions with Fgf22. You can find most of the proteins on our site.

    Function Related Protein
    fibroblast growth factor receptor bindingFgf15;FGF6B;FGF20B;FGF8B;FGF21;FGF18A;FGF22;FGF20A;FGF3
    growth factor activityFGF20B;PRL2C2;TGFB2;GMFG;BMP3;CECR1;REG1A;DKK1;FGF13B

    Fgf22 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Fgf22 here. Most of them are supplied by our site. Hope this information will be useful for your research of Fgf22.

    Yemisci, M; Caban, S; et al. Systemically administered brain-targeted nanoparticles transport peptides across the blood-brain barrier and provide neuroprotection. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM 35:469-475(2015).
    Rashid, H; Ma, CY; et al. Sp7 and Runx2 molecular complex synergistically regulate expression of target genes. CONNECTIVE TISSUE RESEARCH 55:83-87(2014).
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