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Fgf22

Official Full Name

fibroblast growth factor 22
Background

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. The mouse homolog of this gene was found to be preferentially expressed in the inner root sheath of the hair follicle, which suggested a role in hair development.
Synonyms

FGF22; fibroblast growth factor 22; FGF-22;

Type:
Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species :
Human
Mouse
Rhesus Macaque
Zebrafish

Source :
E. coli
E.coli
HEK293
Mammalian Cell

Tag :
Fc
His
His (Fc)
Avi
SUMO(N
ter)
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Price
Human	FGF22-82H	Recombinant Active Human FGF22 Protein, His and SUMO-tagged(N-ter)	E.coli	His and SUMO(N-ter)	Inquiry
Human	FGF22-28879TH	Recombinant Human FGF22	E.coli	N/A	Inquiry
Human	FGF22-86H	Recombinant Human FGF22 Protein	E.coli		Inquiry
Human	FGF22-32H	Active Recombinant Human FGF22 protein, His-tagged	E.coli	His	Inquiry
Human	FGF22-6242HCL	Recombinant Human FGF22 293 Cell Lysate	HEK293	N/A	Inquiry
Human	FGF22-563H	Recombinant Human Fibroblast Growth Factor 22	E.coli	N/A	Inquiry
Human	FGF22-035H	Recombinant Human FGF22 Protein	E. coli		Inquiry
Mouse	FGF22-3234M	Recombinant Mouse FGF22 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	$2,998.00 / 50ug
Mouse	Fgf22-940M	Recombinant Mouse Fgf22 protein, His-tagged	E.coli	His	Inquiry
Mouse	FGF22-3234M-B	Recombinant Mouse FGF22 Protein Pre-coupled Magnetic Beads	HEK293		Inquiry
Mouse	Fgf22-21M	Recombinant Mouse Fibroblast Growth Factor 22, Fc Chimera	Mammalian Cell	Fc	Inquiry
Mouse	FGF22-5850M	Recombinant Mouse FGF22 Protein	Mammalian Cell	His	Inquiry
Rhesus Macaque	FGF22-1520R-B	Recombinant Rhesus Macaque FGF22 Protein Pre-coupled Magnetic Beads	HEK293		Inquiry
Rhesus Macaque	FGF22-1520R	Recombinant Rhesus Macaque FGF22 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	$2,998.00 / 50ug
Rhesus Macaque	FGF22-1698R	Recombinant Rhesus monkey FGF22 Protein, His-tagged	Mammalian Cell	His	Inquiry
Zebrafish	FGF22-3724Z	Recombinant Zebrafish FGF22	Mammalian Cell	His	Inquiry

Fgf22 involved in several pathways and played different roles in them. We selected most pathways Fgf22 participated on our site, such as MAPK signaling pathway, Ras signaling pathway, Rap signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with Fgf22 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
MAPK signaling pathway	PTPN7;GNG12;STK3;MAPK4;GNG12A;FGF17;NR4A1;FGFR4;MAP2K4B
Ras signaling pathway	GNG5;RAPGEF5;FIGF;GNGT2;LOC608458;PAK1;STK4;ANGPT2;PDGFRA
Rap signaling pathway	PIK3CG;GNAS;GNAI2;PDGFC;PRKD2;RAPGEF6;ITGB3;RRAS;PFN3
PIK-Akt signaling pathway	INS1;PPP2R5B;FGF3;FGF17;PPP2R2D;ITGA6;OSMR;PPP2R5E;COL6A4
Regulation of actin cytoskeleton	PIP5K1BA;PAK3;ROCK2B;EGFRA;PIP5K1A;MOS;ITGA3B;RHOAA;MAPK6
Pathways in cancer	ITGA2B;WNT5A;ETS1;WNT7B;LAMA1;MAPK9;LAMA5;F2R;NCOA4
Melanoma	FGF13;PDGFRA;RB1;AKT1;PDGFB;FGF4;FGF17;FGF3;MDM2

Fgf22 has several biochemical functions, for example, fibroblast growth factor receptor binding, growth factor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Fgf22 itself. We selected most functions Fgf22 had, and list some proteins which have the same functions with Fgf22. You can find most of the proteins on our site.

Function	Related Protein
fibroblast growth factor receptor binding	Fgf15;FGF6B;FGF20B;FGF8B;FGF21;FGF18A;FGF22;FGF20A;FGF3
growth factor activity	FGF20B;PRL2C2;TGFB2;GMFG;BMP3;CECR1;REG1A;DKK1;FGF13B

Fgf22 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Fgf22 here. Most of them are supplied by our site. Hope this information will be useful for your research of Fgf22.

Yemisci, M; Caban, S; et al. Systemically administered brain-targeted nanoparticles transport peptides across the blood-brain barrier and provide neuroprotection. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM 35:469-475(2015).

Rashid, H; Ma, CY; et al. Sp7 and Runx2 molecular complex synergistically regulate expression of target genes. CONNECTIVE TISSUE RESEARCH 55:83-87(2014).

FGF Family

FGF Ligands