fgf22

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fgf22

Official Full Name fibroblast growth factor 22
Background The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. The mouse homolog of this gene was found to be preferentially expressed in the inner root sheath of the hair follicle, which suggested a role in hair development.
Synonyms FGF22; fibroblast growth factor 22; FGF-22
    • Type:
    • Species :
    • Human
    • Mouse
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Tag :
    • Fc
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human FGF22-28879TH Recombinant Human FGF22 E.coli N/A
    Human FGF22-32H Recombinant Human FGF22 protein, His-tagged E.coli His
    Human FGF22-563H Recombinant Human Fibroblast Growth Factor 22 E.coli N/A
    Human FGF22-6242HCL Recombinant Human FGF22 293 Cell Lysate HEK293 N/A
    Mouse Fgf22-21M Recombinant Mouse Fibroblast Growth Factor 22, Fc Chimera Mammalian Cell Fc
    Mouse FGF22-5850M Recombinant Mouse FGF22 Protein Mammalian Cell His
    Mouse Fgf22-940M Recombinant Mouse Fgf22 protein, His-tagged E.coli His
    Rhesus Macaque FGF22-1698R Recombinant Rhesus monkey FGF22 Protein, His-tagged Mammalian Cell His
    Zebrafish FGF22-3724Z Recombinant Zebrafish FGF22 Mammalian Cell His

    fgf22 involved in several pathways and played different roles in them. We selected most pathways fgf22 participated on our site, such as MAPK signaling pathway, Ras signaling pathway, Rap signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with fgf22 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    MAPK signaling pathway FGF18; TAOK2; KRAS; FGF21; FGF12; CACNA1H; GNA12; CACNG7A; C11orf52; MAPK8A
    Ras signaling pathway RALGDS; PDGFRA; PRKCG; RASAL1; SHC2; MLLT4; NF1; PLCG1; GNG13; RAC2
    Rap signaling pathway LPAR5; FGFR4; ANGPT4; RAPGEF6; FGF13; PDGFC; ITGB1; VEGFB; PIK3CD; ACTG1
    PIK-Akt signaling pathway LAMC2; PPP2R1B; RHEB; ITGB4; ITGB6; MAP2K2; ITGB5; ITGA4; PPP2R3A; PPP2R5E
    Regulation of actin cytoskeleton PDGFRA; ITGB4; IQGAP2; ITGA3; SLC9A1; RHOAA; PIP5K1A; MYL9A; PXN; PPP1CB
    Pathways in cancer LAMB3; WNT3A; SOS1; MET; CBLB; IKBKG; MLH1; ITGA2B; FZD8; ITGB1
    Melanoma FGF22; NRAS; MAPK1; PIK3R3; PIK3CB; FGF8; PIK3CD; FGF19; CDH1; BRAF

    fgf22 has several biochemical functions, for example, fibroblast growth factor receptor binding, growth factor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by fgf22 itself. We selected most functions fgf22 had, and list some proteins which have the same functions with fgf22. You can find most of the proteins on our site.

    Function Related Protein
    fibroblast growth factor receptor binding FGF18B; FGF10A; Fgf15; FGF6; FGF8A; FGF3; FGF10; FGF21; FRS3; FGF18A
    growth factor activity FGF16; LIF; TGFB1; RABEP2; PRL2C2; TGFB3; HGF; NTF4; CNTF; FGF18A

    fgf22 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with fgf22 here. Most of them are supplied by our site. Hope this information will be useful for your research of fgf22.

    Yemisci, M; Caban, S; et al. Systemically administered brain-targeted nanoparticles transport peptides across the blood-brain barrier and provide neuroprotection. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM 35:469-475(2015).
    Rashid, H; Ma, CY; et al. Sp7 and Runx2 molecular complex synergistically regulate expression of target genes. CONNECTIVE TISSUE RESEARCH 55:83-87(2014).

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