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Official Full Name FK506 binding protein 14, 22 kDa
Background The protein encoded by this gene is a member of the FK506-binding protein family of peptidyl-prolyl cis-trans;isomerases. The encoded protein is found in the lumen of the endoplasmic reticulum, where it is thought to accelerate;protein folding. Defects in this gene are a cause of a type of Ehlers-Danlos syndrome (EDS). Both a protein-coding;variant and noncoding variants are transcribed from this gene.
Synonyms FKBP14; FK506 binding protein 14, 22 kDa; FK506 binding protein 14 (22 kDa); peptidyl-prolyl cis-trans isomerase FKBP14; FKBP22; FLJ20731; 22 kDa FK506 binding protein; 22 kDa FK506-binding protein; 22 kDa FKBP; FK506 binding protein 14; FK506-binding protein 14; FKB14_HUMAN; FKBP 22; FKBP-14; FKBP-22; Peptidyl prolyl cis trans isomerase; PPIase; PPIase FKBP14; Rotamase; OTTHUMP00000122625
    • Species :
    • Human
    • Mouse
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Human Cell
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • Myc/DDK
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human FKBP14-1149HCL Recombinant Human FKBP14 cell lysate Human Cell N/A
    Human FKBP14-1230H Recombinant Human FKBP14 Mammalian Cell His
    Human FKBP14-12908H Recombinant Human FKBP14, GST-tagged E.coli GST
    Human FKBP14-2229H Recombinant Human FKBP14 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human FKBP14-2574H Recombinant Human FK506 Binding Protein 14, 22 kDa, His-tagged E.coli His
    Human FKBP14-28911TH Recombinant Human FKBP14, His-tagged E.coli His
    Human FKBP14-4185H Recombinant Human FKBP14 Protein, GST-tagged Wheat Germ GST
    Human FKBP14-570H Recombinant Human FKBP14, His tagged Human Cell N/A
    Human FKBP14-6197H Recombinant Human FKBP14 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Mouse Fkbp14-3021M Recombinant Mouse Fkbp14 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Mouse FKBP14-5902M Recombinant Mouse FKBP14 Protein Mammalian Cell His
    Rhesus Macaque FKBP14-1717R Recombinant Rhesus monkey FKBP14 Protein, His-tagged Mammalian Cell His
    Zebrafish FKBP14-917Z Recombinant Zebrafish FKBP14 Mammalian Cell His

    fkbp14 involved in several pathways and played different roles in them. We selected most pathways fkbp14 participated on our site, such as IRE1alpha activates chaperones, Metabolism of proteins, Unfolded Protein Response (UPR), which may be useful for your reference. Also, other proteins which involved in the same pathway with fkbp14 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    IRE1alpha activates chaperones CTDSP2; YIF1A; SEC63; HDGF; ADD1; HYOU1; TPP1; KDELR3; SERP1; PDIA6
    Metabolism of proteins EEF1D; RAB27A; FURINA; ST3GAL3A; SLC25A13; CBX8; TIMM21; GALNT5; SEC63; CPB2
    Unfolded Protein Response (UPR) ASNA1; KLHDC3; HYOU1; TPP1; DNAJB9; SERP1; HDGF; YY2; KDELR3; YIF1A
    XBP1(S) activates chaperone genes C19orf10; CXXC1; FKBP14; SEC63; PDIA6; KLHDC3; HYOU1; WIPI1; ASNA1; DNAJB9

    fkbp14 has several biochemical functions, for example, FK506 binding, calcium ion binding, peptidyl-prolyl cis-trans isomerase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by fkbp14 itself. We selected most functions fkbp14 had, and list some proteins which have the same functions with fkbp14. You can find most of the proteins on our site.

    Function Related Protein
    FK506 binding FKBP10; FKBP2; FKBP1AA; FKBP5; FKBP9; FKBP11; FKBP7; FKBP1B; FKBP14; TTC9B
    calcium ion binding PCDH2G5; JAG1B; PLS1; PCDHA8; CAPN11; NUCB2; NUCB1; FLG2; FSTL5; CIB2
    peptidyl-prolyl cis-trans isomerase activity PPIAB; FKBP4; PPIC; PPIAL4B; PPIH; PIN1; PPIAL4C; FKBP1AA; PPIG; PPID

    fkbp14 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with fkbp14 here. Most of them are supplied by our site. Hope this information will be useful for your research of fkbp14.


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