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FZD9

Official Full Name

frizzled family receptor 9
Overview

Members of the frizzled gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins.The FZD9 gene is located within the Williams syndrome common deletion region of chromosome 7, and heterozygous deletion of the FZD9 gene may contribute to the Williams syndrome phenotype.FZD9 is expressed predominantly in brain, testis, eye, skeletal muscle, and kidney.
Synonyms

FZD9; frizzled family receptor 9; frizzled (Drosophila) homolog 9 , frizzled 9, seven transmembrane spanning receptor , frizzled homolog 9 (Drosophila); frizzled-9; CD349; FZD3; fz-9; fzE6; hFz9; frizzled homolog 9; frizzled 9, seven transmembrane spann;

Type

Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Chicken
Gallus gallus (Chicken)
Homo sapiens (Human)
Human
Mouse
Mus musculus (Mouse)
Rhesus monkey

Source

E.coli
E.coli expression system
HEK293
Mammalian Cell
Mammalian cells

Tag

C
Fc
His
GST
hIgG1
hIgG4
His (Fc)
Avi
N/A
N

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	FZD9-13071H	Recombinant Human FZD9, GST-tagged	E.coli	GST	22-246a.a.	$319 / 25ug
Human	FZD9-1541H	Recombinant Human FZD9 Protein, His-tagged	E.coli	N-His	Leu23-Asp229	Inquiry
Human	FZD9-1138H	Recombinant Human FZD9 Protein (Leu23-Ala247), N-His tagged	E.coli	N-His	Leu23-Ala247	Inquiry
Human	FZD9-5202H	Recombinant Human FZD9 Protein (Met1-Asp185), C-Fc tagged	Mammalian cells	C-Fc	Met1-Asp185	Inquiry
Human	FZD9-3809H	Recombinant Human FZD9 protein, His-tagged	E.coli	His	23-247 aa	$319 / 25ug
Human	FZD9-148H	Recombinant Human FZD9 Protein, C-His-tagged	E.coli	C-His		Inquiry
Mouse	FZD9-6123M	Recombinant Mouse FZD9 Protein	Mammalian Cell	His		Inquiry
Mouse	FZD9-3412M-B	Recombinant Mouse FZD9 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Mouse	FZD9-3412M	Recombinant Mouse FZD9 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rhesus monkey	FZD9-1767R	Recombinant Rhesus Monkey FZD9 Protein	HEK293	N/A		Inquiry
Rhesus monkey	FZD9-1768R	Recombinant Rhesus Monkey FZD9 Protein, hIgG1-tagged	HEK293	hIgG1		Inquiry
Rhesus monkey	FZD9-1769R	Recombinant Rhesus Monkey FZD9 Protein, hIgG4-tagged	HEK293	hIgG4		Inquiry
Gallus gallus (Chicken)	RFL16491GF	Recombinant Full Length Chicken Frizzled-9(Fzd9) Protein, His-Tagged	E.coli expression system	His	Full Length (1-392)	Inquiry
Homo sapiens (Human)	RFL8653HF	Recombinant Full Length Human Frizzled-9(Fzd9) Protein, His-Tagged	E.coli expression system	His	Full Length of Mature Protein (23-591)	Inquiry
Mus musculus (Mouse)	RFL21633MF	Recombinant Full Length Mouse Frizzled-9(Fzd9) Protein, His-Tagged	E.coli expression system	His	Full Length of Mature Protein (24-592)	Inquiry
Chicken	FZD9-4701C	Recombinant Chicken FZD9	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
Other Resource
FZD9 Related Signal Pathway

FZD9 involved in several pathways and played different roles in them. We selected most pathways FZD9 participated on our site, such as Wnt signaling pathway, Hippo signaling pathway, Signaling pathways regulating pluripotency of stem cells, which may be useful for your reference. Also, other proteins which involved in the same pathway with FZD9 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Wnt signaling pathway	NLK;TCF7L1A;RUVBL1;CUL1;MAPK8B;WNT4A;CCND2;WNT9A;BAMBIA
Hippo signaling pathway	WNT9A;BMPR1A;BMP6;PPP1CB;AJUBA;WNT8A;BMP8B;MOBKL1A;MOB1A
Signaling pathways regulating pluripotency of stem cells	FZD3;MAP2K1;STAT3;MYF5;GRB2;ID4;INHBB;ID1;JARID2
Melanogenesis	WNT11;CREB3L3A;Kitl;WNT6;FZD3;WNT3A;TCF7L1A;GNAQ;FZD9
HTLV-I infection	CALR;FZD7;EGR2;ANAPC4;PTTG1;TBP;ETS1;FZD1;PPP3CC
Pathways in cancer	WNT9B;MAPK10;IGF1;LPAR4;FGF7;BMP4;RAF1;FGF8;ITGB1
Proteoglycans in cancer	VAV2;FAS;TWIST2;MAPK13;ACTG1;IGF1R;ARAF;PRKACB;MMP9
Basal cell carcinoma	WNT2B;Fzd4;GLI1;FZD8;LEF1;WNT10B;WNT11;HHIP;WNT8B

FZD9 has several biochemical functions, for example, G-protein coupled receptor activity, Wnt-activated receptor activity, Wnt-protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FZD9 itself. We selected most functions FZD9 had, and list some proteins which have the same functions with FZD9. You can find most of the proteins on our site.

Function	Related Protein
G-protein coupled receptor activity	EDNRBA;GHSR;NTSR2;TAAR2;UTS2R;GPR62;DRD1A;CCR6A;GPR186
Wnt-activated receptor activity	LRP6;FZD7B;LRP2A;FZD3B;FZD7A;LRP5;LRP5L;FZD10;FZD8
Wnt-protein binding	FZD10;SFRP4;GPR177;SFRP1B;SZL;FZD6;SFRP1A;FZD3A;FZD1
protein heterodimerization activity	HIST1H2B7;HIST1H2BD;SOX4;CHUK;MCL1;NKX2-5;ERBB2;CEBPA;IRAK2
protein homodimerization activity	BHLHB9;APOBEC3G;TDG;BCL2A;TESCA;RXRB;SNX1;ADRB2;RAB11FIP3

FZD9 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FZD9 here. Most of them are supplied by our site. Hope this information will be useful for your research of FZD9.

Research Area

Wnt Receptors

Neural Stem Cell Markers

Frizzled Receptors

Wang, HX; Tekpetey, FR; et al. Identification of WNT/beta-CATENIN signaling pathway components in human cumulus cells. MOLECULAR HUMAN REPRODUCTION 15:11-17(2009).

Battula, VL; Treml, S; et al. Prospective isolation and characterization of mesenchymal stem cells from human placenta using a frizzled-9-specific monoclonal antibody. DIFFERENTIATION 76:326-336(2008).

Zhang, Z; Schittenhelm, J; et al. Upregulation of frizzled 9 in astrocytomas. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY 32:615-624(2006).