FZD9

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FZD9

Official Full Name frizzled family receptor 9
Background Members of the frizzled gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins.The FZD9 gene is located within the Williams syndrome common deletion region of chromosome 7, and heterozygous deletion of the FZD9 gene may contribute to the Williams syndrome phenotype.FZD9 is expressed predominantly in brain, testis, eye, skeletal muscle, and kidney.
Synonyms FZD9; frizzled family receptor 9; frizzled (Drosophila) homolog 9 , frizzled 9, seven transmembrane spanning receptor , frizzled homolog 9 (Drosophila); frizzled-9; CD349; FZD3; fz-9; fzE6; hFz9; frizzled homolog 9; frizzled 9, seven transmembrane spann
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rhesus monkey
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Tag :
    • GST
    • hIgG1
    • hIgG4
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human FZD9-3809H Recombinant Human FZD9 protein, His-tagged E.coli His
    Human FZD9-13071H Recombinant Human FZD9, GST-tagged E.coli GST
    Mouse FZD9-6123M Recombinant Mouse FZD9 Protein Mammalian Cell His
    Rhesus monkey FZD9-1767R Recombinant Rhesus Monkey FZD9 Protein HEK293 N/A
    Rhesus monkey FZD9-1768R Recombinant Rhesus Monkey FZD9 Protein, hIgG1-tagged HEK293 hIgG1
    Rhesus monkey FZD9-1769R Recombinant Rhesus Monkey FZD9 Protein, hIgG4-tagged HEK293 hIgG4
    Chicken FZD9-4701C Recombinant Chicken FZD9 Mammalian Cell His

    FZD9 involved in several pathways and played different roles in them. We selected most pathways FZD9 participated on our site, such as Wnt signaling pathway, Hippo signaling pathway, Signaling pathways regulating pluripotency of stem cells, which may be useful for your reference. Also, other proteins which involved in the same pathway with FZD9 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Wnt signaling pathway RAC2; FZD7; WNT7A; WNT9A; SERPINF1; PLCB2; SKP1; MAPK9; PSEN1; PRICKLE1
    Hippo signaling pathway WNT6; FGF1; WNT2B; LLGL2; YWHAZ; BMPR1B; WNT3; PRKCZ; FZD7; SMAD7
    Signaling pathways regulating pluripotency of stem cells ACVR1C; NODAL; WNT8B; PAX6; WNT10B; BMPR1A; AKT1; DLX5; MAPK12; WNT2
    Melanogenesis GNA15.4; WNT9B; FZD8A; MAP2K2; GNAI1; EP300; TYRP1B; MITFB; FZD10; CALM3
    HTLV-I infection LTA; WNT8A; NRP1; HLA-DQA1; PIK3R3; HLA-G; PIK3CB; VCAM1; RELA; SPI1
    Pathways in cancer STK4; TRAF6; MAPK9; ARNT; FGF3; HGF; TGFA; F2RL3; FOXO1; ROCK1
    Proteoglycans in cancer PTPN6; WNT5A; LUM; ROCK1; PTK2; FZD5; ELK1; ARAF; ANK1; ITPR3
    Basal cell carcinoma LEF1; FZD7; APC2; GLI2; GSK3B; Shh; WNT2; WNT16; TRP53; TCF7L2

    FZD9 has several biochemical functions, for example, G-protein coupled receptor activity, Wnt-activated receptor activity, Wnt-protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FZD9 itself. We selected most functions FZD9 had, and list some proteins which have the same functions with FZD9. You can find most of the proteins on our site.

    Function Related Protein
    G-protein coupled receptor activity OR10W1; RPA1; OLFR502; TAAR13D; TAAR10C; OR5B2; FZD7B; GPR1; NPFFR1L2; TAS2R123
    Wnt-activated receptor activity FZD9; FZD10; FZD5; FZD7A; FZD3B; FZD3A; FZD3; LRP5L; FZD2; LRP2A
    Wnt-protein binding SFRP1A; SFRP1; LRP5L; ROR2; SMO; LRP2A; FZD8B; FZD10; FZD6; CTHRC1
    protein heterodimerization activity VAPA; SOS1; ZHX3; BAXB; BIK; CABYR; SIM2; MID2; ZFP423; PDGFA
    protein homodimerization activity SLC11A1; PDGFB; CDA; HPRT1; KCNN2; MAP3K5; CORO1A; ACTN1; Bcl2a1b; CADM1

    FZD9 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FZD9 here. Most of them are supplied by our site. Hope this information will be useful for your research of FZD9.

    Wang, HX; Tekpetey, FR; et al. Identification of WNT/beta-CATENIN signaling pathway components in human cumulus cells. MOLECULAR HUMAN REPRODUCTION 15:11-17(2009).
    Battula, VL; Treml, S; et al. Prospective isolation and characterization of mesenchymal stem cells from human placenta using a frizzled-9-specific monoclonal antibody. DIFFERENTIATION 76:326-336(2008).
    Zhang, Z; Schittenhelm, J; et al. Upregulation of frizzled 9 in astrocytomas. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY 32:615-624(2006).

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