Official Full Name | frizzled family receptor 9 |
Background | Members of the frizzled gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins.The FZD9 gene is located within the Williams syndrome common deletion region of chromosome 7, and heterozygous deletion of the FZD9 gene may contribute to the Williams syndrome phenotype.FZD9 is expressed predominantly in brain, testis, eye, skeletal muscle, and kidney. |
Synonyms | FZD9; frizzled family receptor 9; frizzled (Drosophila) homolog 9 , frizzled 9, seven transmembrane spanning receptor , frizzled homolog 9 (Drosophila); frizzled-9; CD349; FZD3; fz-9; fzE6; hFz9; frizzled homolog 9; frizzled 9, seven transmembrane spann |
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
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FZD9 involved in several pathways and played different roles in them. We selected most pathways FZD9 participated on our site, such as Wnt signaling pathway, Hippo signaling pathway, Signaling pathways regulating pluripotency of stem cells, which may be useful for your reference. Also, other proteins which involved in the same pathway with FZD9 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Wnt signaling pathway | RAC2; FZD7; WNT7A; WNT9A; SERPINF1; PLCB2; SKP1; MAPK9; PSEN1; PRICKLE1 |
Hippo signaling pathway | WNT6; FGF1; WNT2B; LLGL2; YWHAZ; BMPR1B; WNT3; PRKCZ; FZD7; SMAD7 |
Signaling pathways regulating pluripotency of stem cells | ACVR1C; NODAL; WNT8B; PAX6; WNT10B; BMPR1A; AKT1; DLX5; MAPK12; WNT2 |
Melanogenesis | GNA15.4; WNT9B; FZD8A; MAP2K2; GNAI1; EP300; TYRP1B; MITFB; FZD10; CALM3 |
HTLV-I infection | LTA; WNT8A; NRP1; HLA-DQA1; PIK3R3; HLA-G; PIK3CB; VCAM1; RELA; SPI1 |
Pathways in cancer | STK4; TRAF6; MAPK9; ARNT; FGF3; HGF; TGFA; F2RL3; FOXO1; ROCK1 |
Proteoglycans in cancer | PTPN6; WNT5A; LUM; ROCK1; PTK2; FZD5; ELK1; ARAF; ANK1; ITPR3 |
Basal cell carcinoma | LEF1; FZD7; APC2; GLI2; GSK3B; Shh; WNT2; WNT16; TRP53; TCF7L2 |
FZD9 has several biochemical functions, for example, G-protein coupled receptor activity, Wnt-activated receptor activity, Wnt-protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FZD9 itself. We selected most functions FZD9 had, and list some proteins which have the same functions with FZD9. You can find most of the proteins on our site.
Function | Related Protein |
---|---|
G-protein coupled receptor activity | OR10W1; RPA1; OLFR502; TAAR13D; TAAR10C; OR5B2; FZD7B; GPR1; NPFFR1L2; TAS2R123 |
Wnt-activated receptor activity | FZD9; FZD10; FZD5; FZD7A; FZD3B; FZD3A; FZD3; LRP5L; FZD2; LRP2A |
Wnt-protein binding | SFRP1A; SFRP1; LRP5L; ROR2; SMO; LRP2A; FZD8B; FZD10; FZD6; CTHRC1 |
protein heterodimerization activity | VAPA; SOS1; ZHX3; BAXB; BIK; CABYR; SIM2; MID2; ZFP423; PDGFA |
protein homodimerization activity | SLC11A1; PDGFB; CDA; HPRT1; KCNN2; MAP3K5; CORO1A; ACTN1; Bcl2a1b; CADM1 |
FZD9 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FZD9 here. Most of them are supplied by our site. Hope this information will be useful for your research of FZD9.
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