GCSH

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GCSH

Official Full Name glycine cleavage system protein H (aminomethyl carrier)
Background Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). The protein encoded by this gene is the H protein, which transfers the methylamine group of glycine from the P protein to the T protein. Defects in this gene are a cause of nonketotic hyperglycinemia (NKH). Two transcript variants, one protein-coding and the other probably not protein-coding,have been found for this gene. Also, several transcribed and non-transcribed pseudogenes of this gene exist throughout the genome.
Synonyms GCSH; glycine cleavage system protein H (aminomethyl carrier); glycine cleavage system H protein, mitochondrial; lipoic acid containing protein; mitochondrial; GCE; GCSH_HUMAN; Glycine cleavage system H protein; Glycine cleavage system H protein mitochondrial; Glycine cleavage system protein H; Mitochondrial glycine cleavage system H protein; NKH; OTTHUMP00000174971; lipoic acid-containing protein; mitochondrial glycine cleavage system H-protein
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Human
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • Myc/DDK
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human GCSH-1281H Recombinant Human Glycine Cleavage System Protein H (Aminomethyl Carrier), His-tagged Human His
    Human GCSH-13202H Recombinant Human GCSH, GST-tagged E.coli GST
    Human GCSH-27469TH Recombinant Human GCSH, His-tagged E.coli His
    Human GCSH-450H Recombinant Human GCSH, His tagged E.coli His
    Human GCSH-4809H Recombinant Human GCSH Protein, GST-tagged Wheat Germ GST
    Human GCSH-5975HCL Recombinant Human GCSH 293 Cell Lysate HEK293 N/A
    Human GCSH-6266H Recombinant Human GCSH Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human GCSH-652H Recombinant Human GCSH Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Mouse Gcsh-3178M Recombinant Mouse Gcsh Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Mouse GCSH-6276M Recombinant Mouse GCSH Protein Mammalian Cell His
    Rat GCSH-2498R Recombinant Rat GCSH Protein Mammalian Cell His
    Chicken GCSH-1191C Recombinant Chicken GCSH Mammalian Cell His

    GCSH involved in several pathways and played different roles in them. We selected most pathways GCSH participated on our site, such as Glycine, serine and threonine metabolism, Glyoxylate and dicarboxylate metabolism, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with GCSH were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Glycine, serine and threonine metabolism ALDH7A1; PSPH; AGXTA; GAMT; SARDH; PGAM1; CBSA; DMGDH; MAOA; PIPOX
    Glyoxylate and dicarboxylate metabolism MCEE; HOGA1; PCCB; MUT; GLULB; MDH1AA; MDH2; GLUL; SHMT1; GCSHA
    Metabolic pathways GAL3ST1; PTGES; NADK; NFS1; GCSHB; INPP4AB; CYP26B1; NT5C; TBXAS1; CS

    GCSH has several biochemical functions, for example, aminomethyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GCSH itself. We selected most functions GCSH had, and list some proteins which have the same functions with GCSH. You can find most of the proteins on our site.

    Function Related Protein
    aminomethyltransferase activity AMT; GCSH

    GCSH has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GCSH here. Most of them are supplied by our site. Hope this information will be useful for your research of GCSH.

    ZBTB16; NMI; ING5

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