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Recombinant Human GCSH Protein, GST-tagged

Cat.No. : GCSH-4809H
Product Overview : Human GCSH full-length ORF ( AAH00790.1, 1 a.a. - 173 a.a.) recombinant protein with GST-tag at N-terminal.
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  • Gene Information
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Description : The enzyme system for cleavage of glycine (glycine cleavage system; EC 2.1.2.10), which is confined to the mitochondria, is composed of 4 protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase; MIM 238300), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme; MIM 238310), and L protein (a lipoamide dehydrogenase; MIM 238331). Glycine encephalopathy (GCE; MIM 605899), also called nonketotic hyperglycinemia (NKH), may be due to a defect in any one of these enzymes.[supplied by OMIM
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 44.77 kDa
AA Sequence : MALRVVRSVRALLCTLRAVPLPAAP CPPRPWQLGVGAVRTLRTGPALLSV RKFTEKHEWVTTENGIGTVGISNFA QEALGDVVYCSLPEVGTKLNKQDEF GALESVKAASELYSPLSGEVTEINE ALAENPGLVNKSCYEDGWLIKMTLS NPSELDELMSEEAYEKYIKSIEE
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : GCSH glycine cleavage system protein H (aminomethyl carrier) [ Homo sapiens ]
Official Symbol : GCSH
Synonyms : GCSH; glycine cleavage system protein H (aminomethyl carrier); glycine cleavage system H protein, mitochondrial; lipoic acid containing protein; lipoic acid-containing protein; mitochondrial glycine cleavage system H-protein; GCE; NKH;
Gene ID : 2653
mRNA Refseq : NM_004483
Protein Refseq : NP_004474
MIM : 238330
UniProt ID : P23434

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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