Recombinant Human GCSH Protein, GST-tagged
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Cat.No. : | GCSH-4809H |
Product Overview : | Human GCSH full-length ORF ( AAH00790.1, 1 a.a. - 173 a.a.) recombinant protein with GST-tag at N-terminal. |
Description : | The enzyme system for cleavage of glycine (glycine cleavage system; EC 2.1.2.10), which is confined to the mitochondria, is composed of 4 protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase; MIM 238300), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme; MIM 238310), and L protein (a lipoamide dehydrogenase; MIM 238331). Glycine encephalopathy (GCE; MIM 605899), also called nonketotic hyperglycinemia (NKH), may be due to a defect in any one of these enzymes.[supplied by OMIM |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 44.77 kDa |
AA Sequence : | MALRVVRSVR ALLCTLRAVP LPAAPCPPRP WQLGVGAVRT LRTGPALLSV RKFTEKHEWV TTENGIGTVG ISNFAQEALG DVVYCSLPEV GTKLNKQDEF GALESVKAAS ELYSPLSGEV TEINEALAEN PGLVNKSCYE DGWLIKMTLS NPSELDELMS EEAYEKYIKS IEE |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Quality Control Testing : |
![]() 12.5% SDS-PAGE Stained with Coomassie Blue. |
Gene Name : | GCSH glycine cleavage system protein H (aminomethyl carrier) [ Homo sapiens ] |
Official Symbol : | GCSH |
Synonyms : | GCSH; glycine cleavage system protein H (aminomethyl carrier); glycine cleavage system H protein, mitochondrial; lipoic acid containing protein; lipoic acid-containing protein; mitochondrial glycine cleavage system H-protein; GCE; NKH; |
Gene ID : | 2653 |
mRNA Refseq : | NM_004483 |
Protein Refseq : | NP_004474 |
MIM : | 238330 |
UniProt ID : | P23434 |
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