GNG5
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Official Full Name
guanine nucleotide binding protein (G protein), gamma 5 -
Synonyms
GNG5;guanine nucleotide binding protein (G protein), gamma 5;guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5;FLJ92393
Recombinant Proteins
- Human
- Zebrafish
- Rhesus macaque
- Rat
- Chicken
- Mouse
- E.coli
- Mammalian Cells
- HEK293
- Wheat Germ
- In Vitro Cell Free System
- GST
- His
- Non
- Avi
- Fc
- DDK
- Myc
- Flag
Involved Pathway
GNG5 involved in several pathways and played different roles in them. We selected most pathways GNG5 participated on our site, such as Ras signaling pathway,Chemokine signaling pathway,PIK-Akt signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with GNG5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Cholinergic synapse | GNB4,PLCB4,HRAS,ITPR3,KCNQ3,PRKCG,GNG10,PIK3CB,AKT2,GNB3 |
| Pathways in cancer | GNAS,TRAF1,FGF18,PIK3R3,GNG11,MSH3,FGF10,MAP2K2,BRAF,RAF1 |
| Alcoholism | CAMKK1,H2AFJ,MAP2K1,HIST2H3C1,HIST1H2AN,GNG2,SLC6A3,H2AFB3,GNAI1,TH |
| Ras signaling pathway | FGF10,RRAS,GRIN1,CALM1,FGFR1,RIN1,PLA2G12B,GAB1,PIK3CB,RELA |
| PIK-Akt signaling pathway | GHR,GRB2,INS2,PPP2R5A,IL2RA,STK11,IL7,CCND1,HGF,PIK3R3 |
| Chemokine signaling pathway | CXCR6,PLCB3,GNB1,CCL7,PTK2B,WAS,CCL19,RAF1,CXCL14,IL-8 |
| Dopaminergic synapse | PPP2R5C,PPP2R3A,PPP2R2D,GNG4,COMT,PPP2CA,MAPK13,GRIA1,PPP2CB,MAPK11 |
| GABAergic synapse | GNB3,GABRG1,GABRB1,GAD1,GABBR1,GABBR2,PRKACB,PRKACA,GNB4,GLUL |
| Retrograde endocannabinoid signaling | GNG12,SLC17A8,GNG8,GABRE,FAAH,GABRG2,MAPK11,GABRG3,SLC17A7,GABRQ |
Protein Function
GNG5 has several biochemical functions, for example, GTPase activity,PDZ domain binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GNG5 itself. We selected most functions GNG5 had, and list some proteins which have the same functions with GNG5. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| PDZ domain binding | GRID2,ATP2B2,LIN7B,USHBP1,Fzd4,FZD2,DLG4,ATP2B4,ATP2B1,SLC22A5 |
| protein binding | NKX3,LRRK1,ZNF397,RSL24D1,LAMTOR3,ISY1,BTK,SZL,LSM4,DDRGK1 |
| GTPase activity | EEF1A1B,RABL2B,RALAB,GPN1,RAB6B,RAB11BA,RAB34,ARL2,RAB39A,RABL2A |
| signal transducer activity | GPR141,MRGPRB4,HTR1AB,GPR52,TAAR14J,PTGER1A,TSPAN6,GNG8,GNAL,TAAR13E |
Interacting Protein
GNG5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GNG5 here. Most of them are supplied by our site. Hope this information will be useful for your research of GNG5.
GOLGA2;TRAF1;KRT31;KRT40;MDFI;EPS15L1;AMOTL2
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References
- Padigel, UM; Stein, L; et al. Signaling through G alpha i2 protein is required for recruitment of neutrophils for antibody-mediated elimination of larval Strongyloides stercoralis in mice. JOURNAL OF LEUKOCYTE BIOLOGY 81:1120-1126(2007).
- Fabbri, E; Selva, C; et al. Identification and properties of a Gs protein in catfish liver membranes. GENERAL AND COMPARATIVE ENDOCRINOLOGY 125:340-348(2002).
