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GPER

Official Full Name

G protein-coupled estrogen receptor 1
Overview

This gene is a member of the G-protein coupled receptor 1 family and encodes a multi-pass membrane protein that localizes to the endoplasmic reticulum. The protein binds estrogen, resulting in intracellular calcium mobilization and synthesis of phosphatidylinositol 3,4,5-trisphosphate in the nucleus. This protein therefore plays a role in the rapid nongenomic signaling events widely observed following stimulation of cells and tissues with estrogen. Alternate transcriptional splice variants which encode the same protein have been characterized.
Synonyms

GPER; G protein-coupled estrogen receptor 1; CMKRL2, G protein coupled receptor 30 , GPR30; G-protein coupled estrogen receptor 1; CEPR; DRY12; FEG 1; GPCR Br; LERGU; LERGU2; LyGPR; mER; heptahelix receptor; chemokine receptor-like 2; IL8-related recepto;

Type

Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Human
Rat

Source

E.coli
HEK293
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

GST
His
His (Fc)
Avi
N/A
N

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	GPER-5532HF	Recombinant Full Length Human GPER Protein, GST-tagged	In Vitro Cell Free System	GST	375 amino acids	Inquiry
Human	GPER-5154H	Recombinant Human GPER Protein	Wheat Germ	N/A		Inquiry
Human	GPER-5230H	Recombinant Human GPER Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	GPER-1580H	Recombinant Human GPER Protein, His&GST-tagged	E.coli	N-His&GST	Met1-Ser62	Inquiry
Human	GPER-5528HF	Recombinant Full Length Human GPER Protein	In Vitro Cell Free System		396 amino acids	Inquiry
Rat	GPER-2637R	Recombinant Rat GPER Protein	Mammalian Cell	His		Inquiry
Rat	GPER-2291R	Recombinant Rat GPER Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rat	GPER-2291R-B	Recombinant Rat GPER Protein Pre-coupled Magnetic Beads	HEK293			Inquiry

GPER Related Articles

GPER involved in several pathways and played different roles in them. We selected most pathways GPER participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with GPER were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

GPER has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by GPER itself. We selected most functions GPER had, and list some proteins which have the same functions with GPER. You can find most of the proteins on our site.

Function	Related Protein

GPER has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GPER here. Most of them are supplied by our site. Hope this information will be useful for your research of GPER.

Chourasia, TK; Pang, YF; et al. The Catecholestrogen, 2-Hydroxyestradiol-17beta, Acts as a G Protein-Coupled Estrogen Receptor 1 (GPER/GPR30) Antagonist to Promote the Resumption of Meiosis in Zebrafish Oocytes. BIOLOGY OF REPRODUCTION 92:-(2015).

Li, YR; Ren, CE; et al. Expression of G protein estrogen receptor (GPER) on membrane of mouse oocytes during maturation. JOURNAL OF ASSISTED REPRODUCTION AND GENETICS 30:227-232(2013).