GPR75

  • Official Full Name

    G protein-coupled receptor 75

  • Overview

    GPR75 is a member of the G protein-coupled receptor family. GPRs are cell surface receptors that activate guanine-nucleotide binding proteins upon the binding of a ligand.
  • Synonyms

    GPR75; G protein-coupled receptor 75; probable G-protein coupled receptor 75; WI 31133; GPRchr2; WI31133; MGC132002;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Assay Kits
  • Homo sapiens (Human)
  • Human
  • Mus musculus (Mouse)
  • Rhesus Macaque
  • E.coli
  • E.coli expression system
  • HEK293
  • In Vitro Cell Free System
  • Mammalian cell
  • Mammalian Cell
  • Wheat Germ
  • Yeast
  • C
  • hFc
  • mFc
  • eGFP, 10His
  • His
  • His (Fc)
  • Avi
  • SUMO
  • N/A
  • N
  • HA
  • Flag
  • 10×His
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human GPR75-40H Recombinant Human GPR75 Protein(Met1-Thr46), hFc-tagged HEK293 C-hFc Met1-Thr46
Human GPR75-3957H Active Recombinant Human GPR75 Full Length Transmembrane protein(Nanodisc) HEK293 N/A
Human GPR75-41H Recombinant Human GPR75 Protein(Met1-Thr46), mFc-tagged HEK293 C-mFc Met1-Thr46
Human GPR75-13487H Recombinant Human GPR75, His-tagged E.coli His 376-540a.a.
Human GPR75-5779HCL Recombinant Human GPR75 293 Cell Lysate HEK293 N/A
Human GPR75-0493H Recombinant Human GPR75 Protein (M1-V540 end), eGFP, 10×His tagged Mammalian cell eGFP, 10His M1-V540 end
Human GPR75-121H Recombinant Human GPR75 protein(GPR75), His-SUMO-tagged E.coli His-SUMO Cytoplasmic Domain
Human GPR75-5262H Recombinant Human GPR75 Protein Wheat Germ N/A
Human GPR75-5630HF Recombinant Full Length Human GPR75 Protein In Vitro Cell Free System 126 amino acids
Human GPR75-122H Recombinant Human GPR75 protein(GPR75), His-tagged Yeast His Cytoplasmic Domain
Human GPR75-17H Recombinant Human GPR75-3C-eGFP Protein (M1-V540 end), N-HA/Flag and C-10×His-tagged Mammalian cell N-HA/Flag and C-10×His M1-V540 end
Homo sapiens (Human) RFL13027HF Recombinant Full Length Human Probable G-Protein Coupled Receptor 75(Gpr75) Protein, His-Tagged E.coli expression system His Full Length (1-540)
Mus musculus (Mouse) RFL2084MF Recombinant Full Length Mouse Probable G-Protein Coupled Receptor 75(Gpr75) Protein, His-Tagged E.coli expression system His Full Length (1-540)
Rhesus Macaque GPR75-1957R Recombinant Rhesus monkey GPR75 Protein, His-tagged Mammalian Cell His
Rhesus Macaque GPR75-1778R Recombinant Rhesus Macaque GPR75 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque GPR75-1778R-B Recombinant Rhesus Macaque GPR75 Protein Pre-coupled Magnetic Beads HEK293
Kit-1325 GPR75 CHO-K1 β-Arrestin Orphan GPCR Assay Kit N/A
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

GPR75 involved in several pathways and played different roles in them. We selected most pathways GPR75 participated on our site, such as GPCRs, Class A Rhodopsin-like, which may be useful for your reference. Also, other proteins which involved in the same pathway with GPR75 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
GPCRs, Class A Rhodopsin-likeOPN1MW2;FPR-RS3;LTB4R;NPFFR2;GPR171;ACKR4;AGTR2;GPR45;OPN1SW

GPR75 has several biochemical functions, for example, C-C chemokine receptor activity, G-protein coupled receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GPR75 itself. We selected most functions GPR75 had, and list some proteins which have the same functions with GPR75. You can find most of the proteins on our site.

Function Related Protein
C-C chemokine receptor activityGPR75;CCR5;CCR3;CCR6;CCR1L1;CCR9;CCR10;CCR8;CCR1
G-protein coupled receptor activityOR12D2;LPAR5;TAAR8B;PTGER4A;HCAR1-2;OR52J3;OLFCH1;OXGR1A.3;OPN1SW2

GPR75 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GPR75 here. Most of them are supplied by our site. Hope this information will be useful for your research of GPR75.

Research Area

Related articles

Coral, S; Covre, A; et al. Epigenetic remodelling of gene expression profiles of neoplastic and normal tissues: immunotherapeutic implications. BRITISH JOURNAL OF CANCER 107:1116-1124(2012).
Robledo, G; Gonzalez-Gay, MA; et al. NPSR1 Gene Is Associated with Reduced Risk of Rheumatoid Arthritis. JOURNAL OF RHEUMATOLOGY 39:1166-1170(2012).
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