gtf2a1
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  • Official Full Name
  • general transcription factor IIA, 1, 19/37kDa
  • Background
  • Accurate transcription initiation on TATA-containing class II genes involves the ordered assembly of RNA polymerase II;(POLR2A; MIM 180660) and several general initiation factors (summarized by DeJong and Roeder, 1993 (PubMed 8224848)).;One of these factors is TFIIA, which when purified from HeLa extracts consists of 35-, 19-, and 12-kD;subunits.
  • Synonyms
  • GTF2A1; general transcription factor IIA, 1, 19/37kDa; glucose regulated protein, 58kD pseudogene; transcription initiation factor IIA subunit 1; TFIIA; General transcription factor IIA 1 19/37kDa; General transcription factor IIA1; Glucose regulated protein 58kD pseudogene; TF2A1; TFIIA 42; TFIIA alpha p55; TFIIA alpha p55, isoform 1; TFIIAL; TFIIA-42; OTTHUMP00000245978; OTTHUMP00000245980; TFIIA alpha, p55, isoform 1; general transcription factor IIA subunit 1; transcription initiation factor TFIIA 42
Cat.#:GTF2A1-4437HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human GTF2A1 Protein, GST-tagged
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Cat.#:GTF2A1-1173HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human GTF2A1, P55, GST-tagged
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Cat.#:GTF2A1-1174HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human General Transcription Factor IIA, 1, 19/37kDa, P12
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Cat.#:GTF2A1-1175HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human General Transcription Factor IIA, 1, 19/37kDa, P55
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Cat.#:GTF2A1-13587HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human GTF2A1, GST-tagged
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Cat.#:GTF2A1-27774THTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human GTF2A1
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Cat.#:GTF2A1-27776THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human GTF2A1, His-tagged
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Cat.#:GTF2A1-7865HTag:His/GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human GTF2A1 protein, His & GST-tagged
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Cat.#:GTF2A1-8476HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human GTF2A1/GTF2A2, His-tagged
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Cat.#:GTF2A1-2739RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat GTF2A1 Protein
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Cat.#:GTF2A1-2000RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey GTF2A1 Protein, His-tagged
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Cat.#:GTF2A1-2870CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken GTF2A1
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Cat.#:GTF2A1-11933ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish GTF2A1
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Cat.#:GTF2A1-1172HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human GTF2A1, P19, GST-tagged
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Cat.#:GTF2A1-1170HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human General Transcription Factor IIA, 1, 19/37kDa
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Cat.#:GTF2A1-1171HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human GTF2A1, P12, GST-tagged
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Cat.#:GTF2A1-762HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human GTF2A1 cell lysate
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Involved Pathway

GTF2A1 involved in several pathways and played different roles in them. We selected most pathways GTF2A1 participated on our site, such as Basal transcription factors, Viral carcinogenesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with GTF2A1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Basal transcription factors
GTF2H2C_2; GTF2A1; TBPL1; GTF2F2A; GTF2H5; TAF7; TAF7L; GTF2B; GTF2A2; TAF5
Viral carcinogenesis
ACTN4; HIST1H2BI; HIST2H2BB; RBPJL; HIST1H4H; CDC42; PRKACG; HIST1H2BL; TBP; PXN

Protein Function

GTF2A1 has several biochemical functions, for example, DNA binding, TBP-class protein binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GTF2A1 itself. We selected most functions GTF2A1 had, and list some proteins which have the same functions with GTF2A1. You can find most of the proteins on our site.
Function
Related Protein
Function DNA binding
Related Protein MIS18BP1; ATF4B1; POLR3F; GSX1; ISL2A; ZNF333; HMGA1B; POU3F2B; ALX4B; BACH1A
Function TBP-class protein binding
Related Protein PSMC3; PSMC1; EFCAB11; DR1; GTF2A2; TAF1L; PSMC5; GTF2A1; THRA; HHEX
Function protein binding
Related Protein C1QTNF9; CCNB1IP1; TSC22D3; UBE2N; CHST13; WDR83; ASIC2; RBL1; FAM19A4; RAB11A
Function protein heterodimerization activity
Related Protein BCL2A1; ADRA1B; ABCG8; TOP2A; BARD1; KATNA1; CEBPA; HIST1H4F; TERF1; HER11
Function transcription coactivator activity
Related Protein SUB1; JUNB; RNF4; RXRB; SMARCA4; ARL2BP; MTA1; E4F1; SAP130; HIF3A
Function transcription factor binding
Related Protein NAB1; HDAC3; PSMC5; POU1F1; HAND1; HDAC11; APBB3; MECP2; SIRT2; C1QBP

Interacting Protein

GTF2A1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GTF2A1 here. Most of them are supplied by our site. Hope this information will be useful for your research of GTF2A1.
GTF2A2; TBPL1; NFYA; TBP; SCHIP1; CREB1; Tbpl1