GTF2H3

  • Official Full Name

    general transcription factor IIH, polypeptide 3, 34kDa
  • Overview

    GTF2H3 is a component of the core-TFIIHC basal transcription factor involved in nucleotide excision repair (NER) of DNA.
  • Synonyms

    GTF2H3;general transcription factor IIH, polypeptide 3, 34kDa;general transcription factor IIH, polypeptide 3 (34kD subunit);general transcription factor IIH subunit 3;BTF2;TFIIH;BTF2 p34;basic transcription factor 2 34 kDa subunit;general transcription factor IIH polypeptide 3;TFIIH basal transcription factor complex p34 subunit;TFB4

Recombinant Proteins

  • Human
  • Rat
  • Chicken
  • Zebrafish
  • E.coli
  • Mammalian Cells
  • Wheat Germ
  • HEK293
  • In Vitro Cell Free System
  • His
  • GST
  • Non
  • Avi
  • Fc
Cat.# Product name Source (Host) Species Tag Protein Length Price
GTF2H3-13598H Recombinant Human GTF2H3 protein, His-tagged E.coli Human His
GTF2H3-2744R Recombinant Rat GTF2H3 Protein Mammalian Cells Rat His
GTF2H3-4450H Recombinant Human GTF2H3 Protein, GST-tagged Wheat Germ Human GST
GTF2H3-4910C Recombinant Chicken GTF2H3 Mammalian Cells Chicken His
GTF2H3-685Z Recombinant Zebrafish GTF2H3 Mammalian Cells Zebrafish His
GTF2H3-5695HCL Recombinant Human GTF2H3 293 Cell Lysate HEK293 Human Non
GTF2H3-2398R Recombinant Rat GTF2H3 Protein, His (Fc)-Avi-tagged HEK293 Rat Avi&Fc&His
GTF2H3-2398R-B Recombinant Rat GTF2H3 Protein Pre-coupled Magnetic Beads HEK293 Rat
GTF2H3-3388HF Recombinant Full Length Human GTF2H3 Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 308 amino acids

    Involved Pathway

    GTF2H3 involved in several pathways and played different roles in them. We selected most pathways GTF2H3 participated on our site, such as Basal transcription factors,Nucleotide excision repair,Viral carcinogenesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with GTF2H3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Nucleotide Excision Repair COPS2,ERCC1,RAD23AB,POLD1,RPA2,POLE,RAD23AA,COPS5,KIAA1530,NFRKB
    Viral carcinogenesis EIF2AK2,TRAF5,HIST3H2BB-PS,STAT5A,H2BFWT,DNAJA3,KAT2A,RHOA,CREB3L2,HIST1H2BG
    Basal transcription factors GTF2H1,GTF2B,CCNH,TAF11,TAF9,TAF1L,TAF8,GTF2H4,GTF2A1,TAF5

    Protein Function

    GTF2H3 has several biochemical functions, for example, contributes_to DNA-dependent ATPase activity,contributes_to RNA polymerase II carboxy-terminal domain kinase activity,damaged DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GTF2H3 itself. We selected most functions GTF2H3 had, and list some proteins which have the same functions with GTF2H3. You can find most of the proteins on our site.

    Function Related Protein
    contributes_to DNA-dependent ATPase activity GTF2H4,GTF2H1,BPTF,MNAT1,ERCC2,GTF2H2,ERCC3,RBBP4
    damaged DNA binding H2AFX,POLK,RAD52,RAD23AA,XPC,TRP53,RAD23B,RPS3,FEN1,RPA3
    protein binding FAM176B,CACNG1,ETV6,ARID3B,RPS3A,ENC1,FEN1,PARD3,TXLNB,MBL2
    contributes_to protein kinase activity GTF2H2,ERCC3,ERCC2,GTF2H4,GTF2H1
    metal ion binding FGD2,TRIM41,PTGS2,FAHD2A,Ar,GGPS1,TRIM35-34,RAB11FIP4,ZNF473,ZNF32
    protein N-terminus binding APTX,ID1,EXOC5,SDCBP,KCNQ2,ERCC3,HESX1,MEN1,PARP1,SMARCE1
    transcription factor activity, sequence-specific DNA binding MNX2A,SOX3,ZNF454,TP53,TP73,ZNF182,ZFP354B,HINFP,FOXO1A,RELA
    translation factor activity, RNA binding EEF1A2,CPEB1A,SOX11,EIF1AX,EIF2S3,EIF4E2,EIF2S2,EEF2K,EIF4G1,EEF1D
    contributes_to RNA polymerase II carboxy-terminal domain kinase activity MNAT1,GTF2H2,ERCC3,GTF2H1,GTF2H4,ERCC2

    Interacting Protein

    GTF2H3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GTF2H3 here. Most of them are supplied by our site. Hope this information will be useful for your research of GTF2H3.

    GTF2H2C;CDK7

    Resources

    References

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