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HAT1

  • Official Full Name

    histone acetyltransferase 1

  • Overview

    The protein encoded by this gene is a type B histone acetyltransferase (HAT) that is involved in the rapid acetylation of newly synthesized cytoplasmic histones, which are in turn imported into the nucleus for de novo deposition onto nascent DNA chains. Histone acetylation, particularly of histone H4, plays an important role in replication-dependent chromatin assembly. Specifically, this HAT can acetylate soluble but not nucleosomal histone H4 at lysines 5 and 12, and to a lesser degree, histone H2A at lysine 5. Alternatively spliced transcript variants have been identified for this gene.
  • Synonyms

    HAT1; histone acetyltransferase 1; histone acetyltransferase type B catalytic subunit; KAT1; HAT 1; HAT1_HUMAN; Histidine aminotransferase 1; OTTHUMP00000163124;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • His|T7
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human HAT1-4586H Recombinant Human HAT1 Protein, GST-tagged Wheat Germ GST
Human HAT1-569H Recombinant Human Histone Acetyltransferase 1, His-tagged E.coli His
Human HAT1-5631HCL Recombinant Human HAT1 293 Cell Lysate HEK293 N/A
Human HAT1-3485HF Recombinant Full Length Human HAT1 Protein, GST-tagged In Vitro Cell Free System GST 334 amino acids
Mouse Hat1-2007M Recombinant Mouse Hat1 protein, His & T7-tagged E.coli His/T7 Glu100~Asp338 (Accession # Q8BY71)
Mouse HAT1-7488M Recombinant Mouse HAT1 Protein Mammalian Cell His
Mouse HAT1-4062M Recombinant Mouse HAT1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse HAT1-4062M-B Recombinant Mouse HAT1 Protein Pre-coupled Magnetic Beads HEK293
Rat HAT1-2793R Recombinant Rat HAT1 Protein Mammalian Cell His
Rat HAT1-2447R-B Recombinant Rat HAT1 Protein Pre-coupled Magnetic Beads HEK293
Rat HAT1-2447R Recombinant Rat HAT1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish HAT1-1294Z Recombinant Zebrafish HAT1 Mammalian Cell His
Chicken HAT1-5781C Recombinant Chicken HAT1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • HAT1 Related Signal Pathway

HAT1 involved in several pathways and played different roles in them. We selected most pathways HAT1 participated on our site, such as Alcoholism, which may be useful for your reference. Also, other proteins which involved in the same pathway with HAT1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
AlcoholismCREB3;CREB3L4;MAPK3;H3F3A;HRAS;HIST1H2AO;GNG2;H2AFB1;HIST1H2AE

HAT1 has several biochemical functions, for example, H4 histone acetyltransferase activity, histone acetyltransferase activity, histone binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HAT1 itself. We selected most functions HAT1 had, and list some proteins which have the same functions with HAT1. You can find most of the proteins on our site.

Function Related Protein
H4 histone acetyltransferase activityNAT15;ELP3;HAT1;NAA60;NAA50;BRCA2
histone acetyltransferase activityGTF3C4;KAT6A;NCOA2;HAT1;CLOCK;TAF1;KAT7A;NCOA1;MGEA5
histone bindingHIST1H4A;HIST2H3C;HIST1H3H;HIST4H4;PIH1D1;UHRF2;SUPT6H;DNAJC2;H3F3A
protein bindingMAPT;RAI2;NAPB;MAGEF1;C5;ECSIT;ZNF511;ZNF423;PSMA6

HAT1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HAT1 here. Most of them are supplied by our site. Hope this information will be useful for your research of HAT1.

MEOX2; vpr; TCF4; REL; RBBP4; TNFAIP1; HIST1H3D

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