|Official Full Name||hemochromatosis|
|Background||Human hemochromatosis protein also known as the HFE protein is a protein which in humans is encoded by the HFE gene. The HFE gene is located on short arm of chromosome 6 at location 6p21.3. Unusually, the official gene symbol (HFE for High Iron Fe) is not an abbreviation of the official name (hemochromatosis)|
|Synonyms||hemochromatosis; HFE; HH; HFE1; HLA-H; MVCD7; TFQTL2; hereditary; hemochromatosis protein; high Fe; MHC class I-like protein HFE; hereditary hemochromatosis protein HLA-H|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
hfe involved in several pathways and played different roles in them. We selected most pathways hfe participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with hfe were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
hfe has several biochemical functions, for example, beta-2-microglobulin binding, co-receptor binding, NOT peptide antigen binding. Some of the functions are cooperated with other proteins, some of the functions could acted by hfe itself. We selected most functions hfe had, and list some proteins which have the same functions with hfe. You can find most of the proteins on our site.
|beta-2-microglobulin binding||CD1D; HFE; FCGRT; CD1E; H2-Q10; HLA-A; CD1B; CD1C; HLA-E; CD1d1|
|co-receptor binding||BMP4; NEO1; DKK1; TFR2; HFE; BMP2|
|NOT peptide antigen binding||FCGRT; HFE|
|protein binding||CD40; NUDT4; LGALS3; PDE4C; FYTTD1; CBLB; TGFB1I1; GORASP2; CSRP2; DVL1|
|receptor binding||MTSS1; RSPO2; FGF13A; ASIP; CHRNA10; PTK6B; F2R; ADCYAP1; WNT2BA; SLC9A3R1|
|transferrin receptor binding||SNX1; RGMA; Trf; HFE; HFE2; SNX2; TF; CD81; SNX4|
hfe has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with hfe here. Most of them are supplied by our site. Hope this information will be useful for your research of hfe.
B2M; TFRC; pnp; q7chd9_yerpe; q81lj8_bacan; iolA2; TF; HSPA5