Recombinant Human HFE Protein, GST-tagged

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Recombinant Human HFE Protein, GST-tagged

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Cat.No. : HFE-4721H
Product Overview : Human HFE partial ORF ( NP_000401, 115 a.a. - 205 a.a.) recombinant protein with GST-tag at N-terminal.
Description : The protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene. At least nine alternatively spliced variants have been described for this gene. Additional variants have been found but their full-length nature has not been determined. [provided by RefSeq
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 35.75 kDa
AA Sequence : SHTLQVILGC EMQEDNSTEG YWKYGYDGQD HLEFCPDTLD WRAAEPRAWP TKLEWERHKI RARQNRAYLE RDCPAQLQQL LELGRGVLDQ Q
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -8 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Quality Control Testing :

12.5% SDS-PAGE Stained with Coomassie Blue.

Gene Name : HFE hemochromatosis [ Homo sapiens ]
Official Symbol : HFE
Synonyms : HFE; hemochromatosis; hereditary hemochromatosis protein; high Fe; HLA H; MHC class I-like protein HFE; hereditary hemochromatosis protein HLA-H; HH; HFE1; HLA-H; MVCD7; TFQTL2; MGC103790; MGC:150812; dJ221C16.10.1; IMAGE:40125754;
Gene ID : 3077
mRNA Refseq : NM_000410
Protein Refseq : NP_000401
MIM : 613609
UniProt ID : Q30201

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