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Official Full Name major histocompatibility complex, class II, DR beta 1
Background The MHC molecule provides a context for the recognition of antigens by T lymphocytes. HLA-DR13 is associated with resistance to hepatitis B virus infection.
Synonyms HLA DRB1; MHC class II antigen HLA DR13; HLA DR13; major histocompatibility complex, class II, DR beta 1
    • Species :
    • Human
    • Mouse
    • Source :
    • E.coli
    • HEK293T
    • Human Cell
    • Tag :
    • Fc
    • GST
    • His
    • SUMO
    • Myc
    • Myc/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human HLA-DRB1-4303H Recombinant Human HLA-DRB1 protein, His-tagged E.coli His
    Human HLA-DRB1-1240H Recombinant Human HLA-DRB1 Protein, His-SUMO/MYC-tagged E.coli His/SUMO/Myc
    Human HLA-DRB1-13822H Recombinant Human HLA-DRB1, GST-tagged E.coli GST
    Human HLA-DRB1-357H Recombinant Human HLA-DRB1 Protein, His-tagged E.coli His
    Human HLA-DRB1-4573H Recombinant Human HLA-DRB1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human HLA-DRB1-488H Recombinant Human major histocompatibility complex, class II, DR beta 1, His-tagged E.coli His
    Human HLA-DRB1-5089H Recombinant Human HLA-DRB1, His-tagged E.coli His
    Human HLA-DRB1-713H Recombinant Human HLA-DRB1, Fc-tagged Human Cell Fc
    Human HLA-DRB1-797HCL Recombinant Human HLA-DRB1 cell lysate N/A
    Mouse HLA-DRB1-358M Recombinant Mouse HLA-DRB1 Protein, His-tagged E.coli His

    HLA-DRB1 involved in several pathways and played different roles in them. We selected most pathways HLA-DRB1 participated on our site, such as Phagosome, Cell adhesion molecules (CAMs), Antigen processing and presentation, which may be useful for your reference. Also, other proteins which involved in the same pathway with HLA-DRB1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Phagosome STX12; ATP6V0A1A; ACTG1; TUBB5; TUBB2B; ITGB1; FAM49BA; DYNC1LI1; ATP6AP1B; MSR1
    Cell adhesion molecules (CAMs) CLDN7; HLA-DRB3; SDC4; SELE; CADM3; NRXN3A; CLDN20; CDH1; ICAM2; CLDN8
    Antigen processing and presentation HLA-DQA1; HLA-DOA; TAP1; HLA-DPB1; NFYC; KIR2DS3; CALR; IFNG; CD8B1; TAP2
    Hematopoietic cell lineage CD37; HLA-DRB3; IL3; Fcer2a; CD36; ITGA3; TFRC; CD1d1; CD3G; CD1D
    Intestinal i BLB2; CCL25; H2-AA; TNFRSF17; CCR9A; CD86; CXCR4A; CXCL12B; ICOSLG; CCR10
    ne network for IgA production BLB1; HLA-DOA; MHC2DEB; MHC2DAB; CD40LG; CXCL12; MADCAM1; CXCR4; IL6; CD40
    Type I diabetes mellitus HLA-E; HLA-DRB1; CPE; HLA-DOA; IL12A; HLA-DPA1; LTA; CD86; IFNG; INS1
    Leishmaniasis STAT1; NCF4; FCGR2C; H2-AA; TGFB1; MAPK13; Itgam&Itgb2; TGFB3; ELK1; IFNG
    Toxoplasmosis BAD; PIK3CG; CD40; IRGM1; SOCS1; IRAK4; Toxoplasma Gondii Microneme Protein MIC3; TGFB1; HSPA1L; LAMB2
    Staphylococcus aureus infection FCGR3A; HLA-DQB1; FPR1; HLA-DQA1; C1R; FCGR2C; DSG1A; HLA-DRB5; ITGB2L; C1S
    Tuberculosis PLK3; TLR1; STAT1; LAMP2; TNF; CALM3; IL12B; SPHK1; LSP1; CD209
    Influenza A IFNA2; RNASEL; IFNA5; IFNA13; PIK3R3; HSPA8; RELA; IFNA21; Ifna15; MAP2K3
    Herpes simplex infection OAS3; IL6; TLR9; HMGN1; IFNA5; HLA-DPB1; HLA-F; TAF13; H2-AB1; C3A.2
    Epstein-Barr virus infection EIF2AK2; TRAF2; POLR3C; TRAF5; GTF2E2; XPO1; PIK3CB; PSMD3; ICAM1; CDK1
    Autoi CD86; HLA-DRB4; HLA-DPB1; HLA-DRB5; CD28; TSHR; CD80; HLA-A; HLA-DMA; IL4
    ne thyroid disease CD28; Fasl; HLA-DRB4; HLA-DQB1; HLA-DMB; IFNA6; TG; TPO; CD80; IFNA8
    Inflammatory bowel disease (IBD) IFNG; Il2; STAT3; H2-AB1; HLA-DPB1; TGFB3; TLR2; Il23a; TGFB1; IFNGR1
    Systemic lupus erythematosus ELANE; ACTN3; HLA-DRB4; H3F3B; HIST1H2AP; HIST1H2AF; HLA-DPA1; CD40LG; HIST1H2AH; HIST1H4C
    Rheumatoid arthritis TLR2; TNF; CCL3; Ctsl; HLA-DPA1; H2-AB1; CXCL5; HLA-DRA; HLA-DRB3; ATP6V0E2
    Allograft rejection Fasl; HLA-DQA1; FAS; IL5; HLA-DPB1; CD80; HLA-DRB4; HLA-C; CD28; GZMB
    Graft-versus-host disease HLA-G; HLA-B; HLA-DRB4; KIR3DL1; FAS; HLA-DOA; HLA-DQB1; PRF1; KLRD1; Fasl
    Viral myocarditis BID; Casp3; HLA-DOA; CD80; ACTG1; RAC1; HLA-DRB5; CD40LG; HLA-DQA1; MYH7

    HLA-DRB1 has several biochemical functions, for example, MHC class II protein complex binding, MHC class II receptor activity, peptide antigen binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HLA-DRB1 itself. We selected most functions HLA-DRB1 had, and list some proteins which have the same functions with HLA-DRB1. You can find most of the proteins on our site.

    Function Related Protein
    MHC class II protein complex binding HLA-DMB; HSPA8; ATP1B1; PKM2; ANXA11; MS4A1; CD74; HLA-DRB1; CD81; HLA-DOB
    MHC class II receptor activity HLA-DQA2; HLA-DRA; HLA-DRB1; HLA-DQB1; HLA-DPA1; HLA-DOB; HLA-DRB4; HLA-DOA; HLA-DRB3; KRT17
    peptide antigen binding MHC1ZDA; MHC1ZFA; TRGV3; CD209; MHC1ZKA; HLA-DRB3; BF2; H2-AA; MAML1; HLA-E
    virus receptor activity SERPINB4; SELPLG; CD209; TFRC; DAG1; CR1; CD80; HTR2A; ITGB5; EFNB2

    HLA-DRB1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HLA-DRB1 here. Most of them are supplied by our site. Hope this information will be useful for your research of HLA-DRB1.


    Bossini-Castillo, L; de Kovel, C; et al. A genome-wide association study of rheumatoid arthritis without antibodies against citrullinated peptides. ANNALS OF THE RHEUMATIC DISEASES 74:-(2015).
    Wagner, CA; Sokolove, J; et al. Identification of anticitrullinated protein antibody reactivities in a subset of anti-CCP-negative rheumatoid arthritis: association with cigarette smoking and HLA-DRB1 'shared epitope' alleles. ANNALS OF THE RHEUMATIC DISEASES 74:579-586(2015).

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