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Official Full Name major histocompatibility complex, class II, DR beta 1
Background The MHC molecule provides a context for the recognition of antigens by T lymphocytes. HLA-DR13 is associated with resistance to hepatitis B virus infection.
Synonyms HLA DRB1; MHC class II antigen HLA DR13; HLA DR13; major histocompatibility complex, class II, DR beta 1
    • Species :
    • Human
    • Mouse
    • Source :
    • E.coli
    • HEK293T
    • Human Cell
    • Tag :
    • Fc
    • GST
    • His
    • SUMO
    • Myc
    • Myc/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human HLA-DRB1-4303H Recombinant Human HLA-DRB1 protein, His-tagged E.coli His
    Human HLA-DRB1-1240H Recombinant Human HLA-DRB1 Protein, His-SUMO/MYC-tagged E.coli His/SUMO/Myc
    Human HLA-DRB1-13822H Recombinant Human HLA-DRB1, GST-tagged E.coli GST
    Human HLA-DRB1-357H Recombinant Human HLA-DRB1 Protein, His-tagged E.coli His
    Human HLA-DRB1-4573H Recombinant Human HLA-DRB1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human HLA-DRB1-488H Recombinant Human major histocompatibility complex, class II, DR beta 1, His-tagged E.coli His
    Human HLA-DRB1-5089H Recombinant Human HLA-DRB1, His-tagged E.coli His
    Human HLA-DRB1-713H Recombinant Human HLA-DRB1, Fc-tagged Human Cell Fc
    Human HLA-DRB1-797HCL Recombinant Human HLA-DRB1 cell lysate N/A
    Mouse HLA-DRB1-358M Recombinant Mouse HLA-DRB1 Protein, His-tagged E.coli His

    hla-drb1 involved in several pathways and played different roles in them. We selected most pathways hla-drb1 participated on our site, such as Phagosome, Cell adhesion molecules (CAMs), Antigen processing and presentation, which may be useful for your reference. Also, other proteins which involved in the same pathway with hla-drb1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Phagosome LAMP2; CTSSA; TUBB2; CALR; Pla2r1; ATP6V1A; ATP6V1H; ITGB3; H2-AB1; ATP6V0D1
    Cell adhesion molecules (CAMs) BLA; PVR; CLDNK; CDH5; CLDN10A; CD99; F11R.1; CLDN18; CLDN9; MPZ
    Antigen processing and presentation KIR2DS2; HLA-DMB; HLA-DRB3; CD74; KIR2DS4; HLA-B; HSPA5; TAPBP; KIR2DS3; HSPA1A
    Hematopoietic cell lineage CD1E; MS4A1; HLA-DRA; GP1BA; GP5; Cd24a; CD38; CD3D; TFRC; Itgam&Itgb2
    Intestinal i Il2; HLA-DRB3; CCR9A; HLA-DRA; PIGR; LTBR; CCL27B; MHC2DCB; MHC2DEB; H2-AB1
    ne network for IgA production TGFB1; HLA-DRB4; HLA-DPB1; CXCR4B; IL-15RA; CCR10; HLA-DRB3; CCL25; BMA2; HLA-DMA
    Type I diabetes mellitus GAD2; INS; FAS; INS1; HLA-DMA; HLA-DRB4; H2-Q10; PTPRN2; H2-AA; HLA-DMB
    Leishmaniasis HLA-DRB5; HLA-DRB3; TGFB2; HLA-DMA; IRAK4; NFKB1; H2-AB1; CR1; HLA-DRB4; PRKCB
    Staphylococcus aureus infection HLA-DOA; ITGB2; C3; H2-AA; ITGAM; FCGR3B; Itgam&Itgb2; FCGR2B; HLA-DOB; FCGR1A
    Tuberculosis LAMP1; FCGR2B; IFNA1; HLA-DQA1; EEA1; IFNB1; IFNA8; Pla2r1; HLA-DRB4; FCGR3
    HTLV-I infection DVL2; FZD8; HRAS; TCF3; HLA-DOA; APC; FZD1; PIK3CG; VAC14; FZD6
    Herpes simplex infection TRAF3; MAPK10; SRSF2; PVRL1; RNASEL; IKBKG; THOC4; FB06F03; CSNK2A2A; TNFB
    Epstein-Barr virus infection LYN; HSPA6; RAN; RBPJL; EIF2AK1; HLA-DQA2; NFKBIB; PRKACA; HLA-DQA1; STAT3
    Autoi Ifna15; CD28; HLA-E; HLA-DRB1; GZMB; FAS; IFNA10; IFNA6; IFNA13; IFNA16
    ne thyroid disease PRF1; IFNA17; IFNA14; HLA-C; Il2; IFNA5; TG; HLA-DRB5; IFNA2; CD80
    Inflammatory bowel disease (IBD) STAT1; IL22; HLA-DMA; IL13; Il2; TGFB2; IL6; IL23R; TBX21; RORA
    Systemic lupus erythematosus HIST1H2BJ; HIST2H4; H2AFV; HIST1H2BI; ACTN2; HIST1H3C; HLA-DRB1; HLA-DRA; HIST1H2AI; C2
    Rheumatoid arthritis TLR4; CTLA4; HLA-DMA; IL-8; CD28; ATP6V0B; ATP6V0D1; TGFB1; IL18; H2-AB1
    Allograft rejection HLA-DOB; HLA-DRA; HLA-DMB; IL4; HLA-DQA1; FASLG; H2-AA; CD80; IL10; HLA-DPB1
    Graft-versus-host disease IL6; FAS; HLA-DRB4; HLA-C; IL1B; KIR2DL3; HLA-DRA; H2-AA; PRF1; Il2
    Viral myocarditis CXADR; ICAM1; HLA-DRB3; RAC3; HLA-DRA; HLA-DPB1; HLA-C; CCND1; CYCS; ACTG1

    hla-drb1 has several biochemical functions, for example, MHC class II protein complex binding, MHC class II receptor activity, peptide antigen binding. Some of the functions are cooperated with other proteins, some of the functions could acted by hla-drb1 itself. We selected most functions hla-drb1 had, and list some proteins which have the same functions with hla-drb1. You can find most of the proteins on our site.

    Function Related Protein
    MHC class II protein complex binding YWHAE; HLA-DRA; PKM2; HLA-DRB1; HLA-DOA; HLA-DMB; HSPA8; HSP90AA1; ATP1B1; CD81
    MHC class II receptor activity HLA-DQA1; HLA-DRB3; HLA-DQB2; HLA-DOB; KRT17; HLA-DQA2; HLA-DQB1; HLA-DRA; HLA-DRB1; HLA-DRB4
    peptide antigen binding BF2; HLA-C; H2-Q10; HLA-E; HLA-DPB1; HLA-A; MAML1; MHC1UDA; MHC1ZBA; MR1
    virus receptor activity GYPA; F11R; EFNB3; IDE; HSPA1B; ITGA2; HLA-DRB1; HYAL2; TNFRSF14; CLEC4M

    hla-drb1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with hla-drb1 here. Most of them are supplied by our site. Hope this information will be useful for your research of hla-drb1.


    Bossini-Castillo, L; de Kovel, C; et al. A genome-wide association study of rheumatoid arthritis without antibodies against citrullinated peptides. ANNALS OF THE RHEUMATIC DISEASES 74:-(2015).
    Wagner, CA; Sokolove, J; et al. Identification of anticitrullinated protein antibody reactivities in a subset of anti-CCP-negative rheumatoid arthritis: association with cigarette smoking and HLA-DRB1 'shared epitope' alleles. ANNALS OF THE RHEUMATIC DISEASES 74:579-586(2015).

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