HMGA1

  • Official Full Name

    high mobility group AT-hook 1
  • Synonyms

    HMGA1;high mobility group AT-hook 1;high mobility group (nonhistone chromosomal) protein isoforms I and Y , HMGIY;high mobility group protein HMG-I/HMG-Y;HMG-I(Y);high mobility group protein R;high mobility group protein A1;nonhistone chromosomal h

Recombinant Proteins

  • Human
  • Rhesus macaque
  • Rat
  • Chicken
  • Mouse
  • E.coli
  • Mammalian Cells
  • Wheat Germ
  • HEK293
  • In Vitro Cell Free System
  • His
  • GST
  • Non
  • DDK
  • Myc
  • Avi
  • Fc
Cat.# Product name Source (Host) Species Tag Protein Length Price
HMGA1-4437H Recombinant Human HMGA1 Protein, His-tagged E.coli Human His 3-107 a.a.
HMGA1-2107R Recombinant Rhesus monkey HMGA1 Protein, His-tagged Mammalian Cells Rhesus macaque His
HMGA1-2865R Recombinant Rat HMGA1 Protein Mammalian Cells Rat His
HMGA1-3597H Recombinant Human HMGA1, His-tagged E.coli Human His
HMGA1-4863H Recombinant Human HMGA1 Protein, GST-tagged Wheat Germ Human GST
HMGA1-5939C Recombinant Chicken HMGA1 Mammalian Cells Chicken His
HMGA1-7725M Recombinant Mouse HMGA1 Protein Mammalian Cells Mouse His
HMGA1-5479HCL Recombinant Human HMGA1 293 Cell Lysate HEK293 Human Non
HMGA1-5480HCL Recombinant Human HMGA1 293 Cell Lysate HEK293 Human Non
Hmga1-1138M Recombinant Mouse Hmga1 Protein, MYC/DDK-tagged HEK293 Mouse DDK&Myc
HMGA1-1690H Recombinant Human HMGA1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293 Human DDK&Myc
Hmga1-174M Recombinant Mouse Hmga1 Protein, His-tagged E.coli Mouse His Met1~Gln107
Hmga1-175R Recombinant Rat Hmga1 Protein, His-tagged E.coli Rat His Met1~Gln107
HMGA1-1928R Recombinant Rhesus Macaque HMGA1 Protein, His (Fc)-Avi-tagged HEK293 Rhesus macaque Avi&Fc&His
HMGA1-1928R-B Recombinant Rhesus Macaque HMGA1 Protein Pre-coupled Magnetic Beads HEK293 Rhesus macaque
HMGA1-2520R Recombinant Rat HMGA1 Protein, His (Fc)-Avi-tagged HEK293 Rat Avi&Fc&His
HMGA1-2520R-B Recombinant Rat HMGA1 Protein Pre-coupled Magnetic Beads HEK293 Rat
HMGA1-3081H Recombinant Human HMGA1 Protein (Glu3-Gln107), His tagged E.coli Human His Glu3-Gln107
HMGA1-3642HF Recombinant Full Length Human HMGA1 Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 96 amino acids
HMGA1-4234M Recombinant Mouse HMGA1 Protein, His (Fc)-Avi-tagged HEK293 Mouse Avi&Fc&His
HMGA1-4234M-B Recombinant Mouse HMGA1 Protein Pre-coupled Magnetic Beads HEK293 Mouse
HMGA1-4435H Recombinant Human HMGA1 Protein, His-tagged E.coli Human His 1-96 a.a.
HMGA1-5225H Recombinant Human HMGA1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293 Human DDK&Myc
HMGA1-5529H Recombinant Human HMGA1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293 Human DDK&Myc
HMGA1-5806H Recombinant Human HMGA1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293 Human DDK&Myc
HMGA1-827H Recombinant Human HMGA1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293 Human DDK&Myc

    Involved Pathway

    HMGA1 involved in several pathways and played different roles in them. We selected most pathways HMGA1 participated on our site, such as 2-LTR circle formation,APOBEC3G mediated resistance to HIV-1 infection,Adipogenesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with HMGA1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cellular Senescence SUZ12B,KDM6B,SUZ12A,AGO3,SUZ12,CBX4,SCMH1,RBB4L,HMGA1B,UBN1
    Adipogenesis NAMPT,EGR2,GADD45A,DLK1,CELF1,NRIP1,BMP1,KLF7A,SMAD3B,GDF10
    APOBEC3G mediated resistance to HIV-1 infection BANF1,APOBEC3G,gag,PSIP1,PPIA
    Autointegration results in viral DNA circles gag,PSIP1,BANF1
    Cellular responses to stress HSPA7,DNAJC2,CDKN2B,ATG7,HIF1AL,NUP35,PHC1,HSBP1B,ATG9A,HSBP1A
    DNA Damage/Telomere Stress Induced Senescence H1F0,TERF2,ASF1A,HIST1H1C,CABIN1,TINF2,HIST1H1E,HMGA1B,TERF2IP,TERF1
    2-LTR circle formation BANF1,PSIP1,gag
    Disease OPN1LW,FMOD,TRAT1,TICAM1,FGFR1OP2,NMT1,RBP1,BANF1,DOCK2,CDK9

    Protein Function

    HMGA1 has several biochemical functions, for example, 5-deoxyribose-5-phosphate lyase activity,AT DNA binding,DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HMGA1 itself. We selected most functions HMGA1 had, and list some proteins which have the same functions with HMGA1. You can find most of the proteins on our site.

    Function Related Protein
    5-deoxyribose-5-phosphate lyase activity HMGA1-RS1,XRCC6,HMGA2
    transcription factor binding Ar,SP1,NKX3,FOSB,TMEM173,NCOR2,CREG1,H2-AB1,PAX2,RBPJ
    protein binding GNG10,CYSLTR2,HTR6,RALYL,RORA,MYOZ1,C9orf16,DIS3,DCAF12L1,NUBP2
    enzyme binding TOP2A,ATG3,MLEC,CAV1,JUN,TAF10,HDHD2,UGT1A4,CALU,ADORA2A
    transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding ZEB2,NFKB1,CUX1,SPI1,SFPI1,PROP1,NFE2L1,PBX3,NFE2L2,BACH1
    retinoic acid receptor binding NSD1,PRAMEF10,ACTN4,PRAMEF6,PRAME,MED1,SNW1,ASXL1,PRMT2,PRAMEF2
    chromatin binding KAT2A,SSBP1,MBD5,OVOL2,RAG2,PKN1,JUN,SOD3,FOS,ING2
    AT DNA binding MEF2C,POU3F4,CRIP1,HMGA2
    DNA binding HOXD10A,PEG10,UBN1,RCOR3,SPO11,HIST1H2B7,ERCC3,XBP1,TRIM30A,STAT1B

    Interacting Protein

    HMGA1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HMGA1 here. Most of them are supplied by our site. Hope this information will be useful for your research of HMGA1.

    SP1;CEBPB;il2ra_human_gene;il2ra_human_+3317/+3478_dna-probe;Stag2;HSP90AB1;HTT;EWSR1;Kifc5b;ssdna_dadts

    Resources

    References

    • Chieffi, P; Chieffi, S; et al. Molecular biomarkers as potential targets for therapeutic strategies in human testicular germ cell tumors: An overview. JOURNAL OF CELLULAR PHYSIOLOGY 228:1641-1646(2013).
    • Chieffi, P; et al. New Prognostic Markers and Potential Therapeutic Targets in Human Testicular Germ Cell Tumors. CURRENT MEDICINAL CHEMISTRY 18:5033-5040(2011).

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