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Official Full Name hydroxysteroid (17-beta) dehydrogenase 11
Background Short-chain alcohol dehydrogenases, such as HSD17B11, metabolize secondary alcohols and ketones (Brereton et al., 2001;(PubMed 11165019)).
Synonyms HSD17B11; hydroxysteroid (17-beta) dehydrogenase 11; dehydrogenase/reductase (SDR family) member 8 , DHRS8; estradiol 17-beta-dehydrogenase 11; 17 BETA HSD11; 17 BETA HSDXI; PAN1B; retinal short chain dehydrogenase/reductase 2; RetSDR2; SDR16C2; short cha
    • Species :
    • Cynomolgus Monkey
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • MYC/DDK
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human HSD17B11-13955H Recombinant Human HSD17B11, His-tagged E.coli His
    Human HSD17B11-2131H Recombinant Human HSD17B11 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human HSD17B11-28398TH Recombinant Human HSD17B11, His-tagged E.coli His
    Human HSD17B11-3548H Recombinant Human HSD17B11 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human HSD17B11-473HCL Recombinant Human HSD17B11 cell lysate N/A
    Human HSD17B11-5066H Recombinant Human HSD17B11 Protein, GST-tagged Wheat Germ GST
    Human HSD17B11-943H Recombinant Human HSD17B11, 20-285 aa, His-tagged E.coli His
    Mouse Hsd17b11-524M Recombinant Mouse Hsd17b11 Protein, MYC/DDK-tagged HEK293T MYC/DDK
    Rat HSD17B11-2923R Recombinant Rat HSD17B11 Protein Mammalian Cell His
    Cynomolgus Monkey HSD17B11-598C Recombinant Cynomolgus HSD17B11 Protein, His-tagged Mammalian Cell His
    Rhesus Macaque HSD17B11-2154R Recombinant Rhesus monkey HSD17B11 Protein, His-tagged Mammalian Cell His

    hsd17b11 involved in several pathways and played different roles in them. We selected most pathways hsd17b11 participated on our site, such as Estrogen biosynthesis, Metabolism, Metabolism of lipids and lipoproteins, which may be useful for your reference. Also, other proteins which involved in the same pathway with hsd17b11 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Estrogen biosynthesis CYP19A1; HSD17B11; AKR1B15
    Metabolism SULT1C4; GCKR; DGAT1B; HAS3; KCNS3; CTRC; SLC25A15A; CTRB1; DUT; GNG13A
    Metabolism of lipids and lipoproteins SLC25A1; FABP9; NFYBB; PEMT; COL4A3BP; SGMS2; CYP27A1; MED29; ACOT9.2; CLPS
    Metabolism of steroid hormones and vitamin D CYP27B1; CYP24A1; PPP1R2; GC; CYP2R1; HSD17B11; STARD5; AKR1B15
    estradiol biosynthesis I HSD17B11
    superpathway of steroid hormone biosynthesis HSD17B11

    hsd17b11 has several biochemical functions, for example, estradiol 17-beta-dehydrogenase activity, steroid dehydrogenase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by hsd17b11 itself. We selected most functions hsd17b11 had, and list some proteins which have the same functions with hsd17b11. You can find most of the proteins on our site.

    Function Related Protein
    estradiol 17-beta-dehydrogenase activity RDH8A; HSD17B12A; HSD17B6; HSD17B2; HSD17B11; AKR1C6; HSD17B12B; HSD17B10; AKR1B15; HSD17B8
    steroid dehydrogenase activity AKR1C21; HSD3B5; HSD17B11; SDR42E1; AKR1C6; H2-KE6; SDR16C6; HSD3B6; HSD11B1LA

    hsd17b11 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with hsd17b11 here. Most of them are supplied by our site. Hope this information will be useful for your research of hsd17b11.

    PTP4A3; BRF2; GSTK1

    Legeza, B; Balazs, Z; et al. The Microsomal Enzyme 17 beta-Hydroxysteroid Dehydrogenase 3 Faces the Cytoplasm and Uses NADPH Generated by Glucose-6-Phosphate Dehydrogenase. ENDOCRINOLOGY 154:205-213(2013).
    Patel, K; Farlow, EC; et al. Enhancement of a multianalyte serum biomarker panel to identify lymph node metastases in non-small cell lung cancer with circulating autoantibody biomarkers. INTERNATIONAL JOURNAL OF CANCER 129:133-142(2011).

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