Recombinant Mouse Hsd17b11 Protein, MYC/DDK-tagged

• Cat.No.: Hsd17b11-524M
• Product Overview: Purified recombinant protein of full-length mouse hydroxysteroid (17-beta) dehydrogenase 11 (Hsd17b11), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Can convert androstan-3-alpha,17-beta-diol (3-alpha-diol) to androsterone in vitro, suggesting that it may participate in androgen metabolism during steroidogenesis. May act by metabolizing compounds that stimulate steroid synthesis and/or by generating metabolites that inhibit it. Has no activity toward DHEA (dehydroepiandrosterone), or A-dione (4-androste-3,17-dione), and only a slight activity toward testosterone to A-dione.
• Source: HEK293T
• Species: Mouse
• Tag: MYC/DDK
• Molecular Mass: 32.9 kDa
• Purity: >80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Hsd17b11 hydroxysteroid (17-beta) dehydrogenase 11 [ Mus musculus (house mouse) ]
• Official Symbol: Hsd17b11
• Synonyms: Hsd17b11; hydroxysteroid (17-beta) dehydrogenase 11; SDR2; Dhrs8; Pan1b; retSDR2; estradiol 17-beta-dehydrogenase 11; 17-beta-HSD 11
  17-beta-HSD XI; 17-beta-hydroxysteroid dehydrogenase 11; 17-beta-hydroxysteroid dehydrogenase XI; 17bHSD11; 17beta-HSD11; 17betaHSD11; 17betaHSDXI; dehydrogenase/reductase (SDR family) member 8; retinal short-chain dehydrogenase/reductase 2; retinal short-chain dehydrogenase/reductase SDR2; EC 1.1.1.62
• Gene ID: 114664
• mRNA Refseq: NM_053262
• Protein Refseq: NP_444492
• UniProt ID: Q9EQ06