Recombinant Human IGF2BP1, MYC/DDK-tagged

• Cat.No.: IGF2BP1-106H
• Product Overview: Recombinant Human IGF2BP1, fused with C-terminal MYC/DDK, was expressed in HEK293 Cells.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: This gene encodes a member of the insulin-like growth factor 2 mRNA-binding protein family. The protein encoded by this gene contains four K homology domains and two RNA recognition motifs. It functions by binding to the mRNAs of certain genes, including insulin-like growth factor 2, beta-actin and beta-transducin repeat-containing protein, and regulating their translation. Two transcript variants encoding different isoforms have been found for this gene.
• Molecular Mass: 63.3 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: IGF2BP1 insulin-like growth factor 2 mRNA binding protein 1 [ Homo sapiens (human) ]
• Official Symbol: IGF2BP1
• Synonyms: IGF2BP1; IMP1; ZBP1; CRDBP; IMP-1; CRD-BP; VICKZ1; insulin-like growth factor 2 mRNA binding protein 1; insulin-like growth factor 2 mRNA-binding protein 1; ZBP-1; VICKZ family member 1; zipcode-binding protein 1; IGF2 mRNA-binding protein 1; IGF-II mRNA-binding protein 1; coding region determinant-binding protein
• Gene ID: 10642
• mRNA Refseq: NM_006546
• Protein Refseq: NP_006537
• MIM: 608288
• UniProt ID: Q9NZI8
• Chromosome Location: 17q21.32
• Pathway: BDNF signaling pathway; Binding of RNA by Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs); MicroRNAs in cancer
• Function: mRNA 3'-UTR binding; mRNA binding; nucleotide binding