• Official Full Name

    interleukin 1 receptor-like 1

  • Overview

    The protein encoded by this gene is a member of the interleukin 1 receptor family. Studies of the similar gene in mouse suggested that this receptor can be induced by proinflammatory stimuli, and may be involved in the function of helper T cells. This gene, interleukin 1 receptor, type I (IL1R1), interleukin 1 receptor, type II (IL1R2) and interleukin 1 receptor-like 2 (IL1RL2) form a cytokine receptor gene cluster in a region mapped to chromosome 2q12. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008]
  • Synonyms

    IL1RL1; interleukin 1 receptor-like 1; T1; ST2; DER4; ST2L; ST2V; FIT-1; IL33R; interleukin-1 receptor-like 1; growth stimulation-expressed; interleukin 1 receptor-related protein; homolog of mouse growth stimulation-expressed;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Antibody
  • Chicken
  • Cynomolgus
  • Human
  • Mouse
  • Mus musculus (Mouse)
  • Rat
  • CHO
  • E.coli
  • E.coli expression system
  • HEK293
  • Human
  • Human Cell
  • Human cells
  • Mammalian Cell
  • Mammalian cells
  • Rabbit
  • Sf21 Insect Cell
  • C
  • Fc
  • hFc
  • His
  • DDK
  • DDK|His
  • Fc Chimera
  • Avi
  • Flag
  • His (Fc)
  • human|IgG1|Fc
  • N/A
  • N
  • T7|His
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human IL1RL1-436H Active Recombinant Human IL1RL1, Fc Chimera Mammalian cells Fc Chimera
Human IL1RL1-629H Active Recombinant Human IL1RL1, His-tagged, Biotinylated Human Cell His
Human IL1RL1-505H Active Recombinant Mouse IL1RL1, HIgG1 Fc-tagged CHO Fc
Human IL1RL1-502H Active Recombinant Human IL1RL1, Fc-tagged HEK293 Fc
Human IL1RL1-774H Active Recombinant Human IL1RL1 protein(Met1-Phe328), hFc-tagged HEK293 C-hFc Met1-Phe328
Human IL1RL1-3991H Active Recombinant Human IL1RL1 protein, His-tagged HEK293 His Met1-Ser328
Human IL1RL1-773H Recombinant Human IL1RL1 protein, Fc-tagged HEK293 human/IgG1/Fc 305
Human IL1RL1-144H Recombinant Human IL1RL1 protein, T7/His-tagged E.coli T7/His
Human IL1RL1-501H Recombinant Human IL1RL1, FLAG-tagged HEK293 Flag
Human IL1RL1-30316TH Recombinant Human IL1RL1, His-tagged E.coli His
Human IL1RL1-535H Recombinant Human IL1RL1 Protein, DDK/His-tagged HEK293 DDK/His
Human IL1RL1-537H Recombinant Human IL1RL1 Protein, DDK-tagged CHO DDK
Human IL1RL1-1637H Recombinant Human Interleukin 1 Receptor-Like 1 Mammalian cells N/A
Human IL1RL1-775H Recombinant Human IL1RL1 protein(Met1-Phe328) HEK293 N/A Met1-Phe328
Human IL1RL1-536H Recombinant Human IL1RL1 Protein, His-tagged HEK293 His
Human IL1RL1-396H Recombinant Human Interleukin 1 Receptor-Like 1, His-tagged Human His
Human IL1RL1-1883HCL Recombinant Human IL1RL1 cell lysate Human Cell N/A
Human IL1RL1-2481HCL Recombinant Human IL1RL1 cell lysate Human Cell N/A
Human IL1RL1-3221H Recombinant Human IL1RL1 Protein (His162-Ile349), N-His tagged E.coli N-His His162-Ile349
Human IL1RL1-1009H Active Recombinant Human ST2 Protein Human cells His
Human IL1RL1-195H Recombinant Human IL1RL1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human IL1RL1-1853H Active Recombinant Human IL1RL1 protein, Fc & Avi-tagged, Biotinylated HEK293 Fc/Avi Lys 19 - Pro 323
Human IL1RL1-5288H Recombinant Human IL1RL1 Protein (Lys19-Pro323), C-His tagged Mammalian cells C-His Lys19-Pro323
Human IL1RL1-1857H Active Recombinant Human IL1RL1 protein, His & Avi-tagged, Biotinylated HEK293 His & Avi Lys 19 - Pro 323
Human IL1RL1-317H Recombinant Human IL1RL1 Protein, His-tagged HEK293 His 556
Human IL1RL1-195H-B Recombinant Human IL1RL1 Protein Pre-coupled Magnetic Beads HEK293
Human CAB11565RH Rabbit Anti-Human Interleukin 1 Receptor-like 1 Monoclonal Antibody Rabbit N/A
Human IL1RL1-5287H Recombinant Human IL1RL1 Protein (Lys19-Phe328), C-His tagged Mammalian cells C-His Lys19-Phe328
Human IL1RL1-318H Recombinant Human IL1RL1 Protein, Fc-tagged HEK293 Fc 556
Mouse IL1RL1-503M Active Recombinant Mouse IL1RL1, MIgG2a Fc-tagged CHO Fc
Mouse Il1rl1-515M Recombinant Mouse Il1rl1, Fc-tagged Human Cell Fc Met1-Arg332
Mouse Il1rl1-516M Recombinant Mouse Il1rl1, His-tagged Human Cell His Met1-Arg332
Mouse Il1rl1-1752M Recombinant Mouse Interleukin 1 Receptor-like 1, Fc-tagged Sf21 Insect Cell Fc
Mouse IL1RL1-001MCL Recombinant Mouse IL1RL1 cell lysate Human Cell N/A
Mouse IL1RL1-6811M Recombinant Mouse IL1RL1 Protein (Lys19-Phe328), C-His tagged Mammalian cells C-His Lys19-Phe328
Mouse Il1rl1-5714M Recombinant Mouse Il1rl1 Protein (Ser27-Ala337), C-Fc tagged Mammalian cells C-Fc Ser27-Ala337
Rat IL1RL1-3035R Recombinant Rat IL1RL1 Protein Mammalian Cell His
Rat IL1RL1-2690R Recombinant Rat IL1RL1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat IL1RL1-2690R-B Recombinant Rat IL1RL1 Protein Pre-coupled Magnetic Beads HEK293
Cynomolgus IL1RL1-25C Recombinant Cynomolgus IL1RL1 protein (Met1-Cys331), His-tagged HEK293 His
Mus musculus (Mouse) RFL10426MF Recombinant Full Length Mouse Interleukin-1 Receptor-Like 1(Il1Rl1) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (27-567)
Chicken IL1RL1-2191C Recombinant Chicken IL1RL1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

IL1RL1 involved in several pathways and played different roles in them. We selected most pathways IL1RL1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with IL1RL1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

IL1RL1 has several biochemical functions, for example, cytokine receptor activity, interleukin-1 receptor activity, interleukin-33 binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IL1RL1 itself. We selected most functions IL1RL1 had, and list some proteins which have the same functions with IL1RL1. You can find most of the proteins on our site.

Function Related Protein
cytokine receptor activityIL11RA;CRFB17;GHRA;IL20RB;IL2RGA;CRFB16;CRFB15;CSF3R;IL4R.1
interleukin-1 receptor activityIL1RL2;IL1R1;IL1RL1;IL18R1;IL1RAPL1A;IL1RAP;IL1RAPL2;IL1R2
interleukin-33 binding
interleukin-33 receptor activity
receptor signaling protein activityNSMAF;FCGR1A;DOK4;KLK1B4;BAG4;IFITM1;RAF1A;TIAM2;TYROBP

IL1RL1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IL1RL1 here. Most of them are supplied by our site. Hope this information will be useful for your research of IL1RL1.


Gene Family


Research Area

Related articles

Seeber, S; Ros, F; et al. A Robust High Throughput Platform to Generate Functional Recombinant Monoclonal Antibodies Using Rabbit B Cells from Peripheral Blood. PLOS ONE 9:-(2014).
Gillibert-Duplantier, J; Duthey, B; et al. Gene expression profiling identifies sST2 as an effector of ErbB2-driven breast carcinoma cell motility, associated with metastasis. ONCOGENE 31:3516-3524(2012).
  • Q&As
  • Reviews

Q&As (10)

Ask a question
Are there any splice variants of IL1RL1? 02/20/2022

IL1RL1 has multiple splice variants that differ in signaling capabilities.

What is the role of IL1RL1 in allergic responses? 11/15/2021

IL1RL1 suppresses allergic responses by inhibiting mast cell activation.

Does IL1RL1 have a role in autoimmune diseases? 10/09/2021

IL1RL1 is implicated in rheumatoid arthritis.

How does IL1RL1 affect cytokine production? 11/21/2020

IL1RL1 increases the production of IL-4 and IL-13.

What is the subcellular localization of IL1RL1? 08/13/2020

IL1RL1 is primarily membrane-bound.

Does IL1RL1 influence T-cell differentiation? 02/29/2020

IL1RL1 promotes Th2 cell differentiation.

How does IL1RL1 interact with its ligands? 01/17/2020

IL1RL1 binds to IL-33 and IL-36 to initiate signaling.

Is IL1RL1 expression altered in any cancers? 05/09/2018

IL1RL1 expression is altered in lung and breast cancer.

What post-translational modifications occur on IL1RL1? 03/28/2017

IL1RL1 undergoes glycosylation and phosphorylation.

How is IL1RL1 expression regulated in asthmatic conditions? 08/23/2016

IL1RL1 expression is upregulated in asthmatic conditions.

Customer Reviews (3)

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    High specificity in ELISA.


      Suitable for flow cytometry.


        Effective in allergy models.

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