• Official Full Name

    interleukin 1 receptor-like 1

  • Background

    The protein encoded by this gene is a member of the interleukin 1 receptor family. Studies of the similar gene in mouse suggested that this receptor can be induced by proinflammatory stimuli, and may be involved in the function of helper T cells. This gene, interleukin 1 receptor, type I (IL1R1), interleukin 1 receptor, type II (IL1R2) and interleukin 1 receptor-like 2 (IL1RL2) form a cytokine receptor gene cluster in a region mapped to chromosome 2q12. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008]
  • Synonyms

    IL1RL1; interleukin 1 receptor-like 1; T1; ST2; DER4; ST2L; ST2V; FIT-1; IL33R; interleukin-1 receptor-like 1; growth stimulation-expressed; interleukin 1 receptor-related protein; homolog of mouse growth stimulation-expressed;
    • Type:
    • Recombinant Proteins
    • Cell & Tissue Lysates
    • Antibody
    • Protein Pre-coupled Magnetic Beads
    • Species :
    • Chicken
    • Cynomolgus
    • Human
    • Mouse
    • Mus musculus (Mouse)
    • Rat
    • Source :
    • CHO
    • E.coli
    • E.coli expression system
    • HEK293
    • Human
    • Human Cell
    • Human cells
    • Mammalian Cell
    • Mammalian cells
    • Rabbit
    • Sf21 Insect Cell
    • Tag :
    • DDK
    • DDK|His
    • Fc
    • Fc Chimera
    • Avi
    • Flag
    • His
    • His (Fc)
    • human|IgG1|Fc
    • N/A
    • T7|His
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Chicken IL1RL1-2191C Recombinant Chicken IL1RL1 Mammalian Cell His
    Cynomolgus IL1RL1-25C Recombinant Cynomolgus IL1RL1 protein (Met1-Cys331), His-tagged HEK293 His
    Human IL1RL1-3991H Recombinant Human IL1RL1 protein, His-tagged HEK293 His
    Human IL1RL1-1883HCL Recombinant Human IL1RL1 cell lysate Human Cell N/A
    Human CAB11565RH Rabbit Anti-Human Interleukin 1 Receptor-like 1 Monoclonal Antibody Rabbit N/A
    Human IL1RL1-1853H Recombinant Human IL1RL1 protein, Fc & Avi-tagged, Biotinylated HEK293 Fc/Avi
    Human IL1RL1-30316TH Recombinant Human IL1RL1, His-tagged E.coli His
    Human IL1RL1-774H Recombinant Human IL1RL1, Fc tagged Human Cell Fc
    Human IL1RL1-502H Active Recombinant Human IL1RL1, Fc-tagged HEK293 Fc
    Human IL1RL1-773H Recombinant Human IL1RL1 protein, Fc-tagged HEK293 human/IgG1/Fc
    Human IL1RL1-775H Recombinant Human IL1RL1, None tagged Human Cell N/A
    Human IL1RL1-501H Recombinant Human IL1RL1, FLAG-tagged HEK293 Flag
    Human IL1RL1-144H Recombinant Human IL1RL1 protein, T7/His-tagged E.coli T7/His
    Human IL1RL1-535H Recombinant Human IL1RL1 Protein, DDK/His-tagged HEK293 DDK/His
    Human IL1RL1-396H Recombinant Human Interleukin 1 Receptor-Like 1, His-tagged Human His
    Human IL1RL1-1637H Recombinant Human Interleukin 1 Receptor-Like 1 Mammalian cells N/A
    Human IL1RL1-537H Recombinant Human IL1RL1 Protein, DDK-tagged CHO DDK
    Human IL1RL1-536H Recombinant Human IL1RL1 Protein, His-tagged HEK293 His
    Human IL1RL1-629H Active Recombinant Human IL1RL1, His-tagged, Biotinylated Human Cell His
    Human IL1RL1-505H Active Recombinant Mouse IL1RL1, HIgG1 Fc-tagged CHO Fc
    Human IL1RL1-195H Recombinant Human IL1RL1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
    Human IL1RL1-2481HCL Recombinant Human IL1RL1 cell lysate Human Cell N/A
    Human IL1RL1-317H Recombinant Human IL1RL1 Protein, His-tagged HEK293 His
    Human IL1RL1-1009H Recombinant Human ST2 Protein Human cells His
    Human IL1RL1-318H Recombinant Human IL1RL1 Protein, Fc-tagged HEK293 Fc
    Human IL1RL1-436H Active Recombinant Human IL1RL1, Fc Chimera Mammalian cells Fc Chimera
    Human IL1RL1-1857H Recombinant Human IL1RL1 protein, His & Avi-tagged, Biotinylated HEK293 His & Avi
    Human IL1RL1-195H-B Recombinant Human IL1RL1 Protein Pre-coupled Magnetic Beads HEK293
    Mouse IL1RL1-001MCL Recombinant Mouse IL1RL1 cell lysate Human Cell N/A
    Mouse Il1rl1-516M Recombinant Mouse Il1rl1, His-tagged Human Cell His
    Mouse Il1rl1-515M Recombinant Mouse Il1rl1, Fc-tagged Human Cell Fc
    Mouse IL1RL1-503M Active Recombinant Mouse IL1RL1, MIgG2a Fc-tagged CHO Fc
    Mouse Il1rl1-1752M Recombinant Mouse Interleukin 1 Receptor-like 1, Fc-tagged Sf21 Insect Cell Fc
    Mus musculus (Mouse) RFL10426MF Recombinant Full Length Mouse Interleukin-1 Receptor-Like 1(Il1Rl1) Protein, His-Tagged E.coli expression system His
    Rat IL1RL1-3035R Recombinant Rat IL1RL1 Protein Mammalian Cell His
    Rat IL1RL1-2690R Recombinant Rat IL1RL1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
    Rat IL1RL1-2690R-B Recombinant Rat IL1RL1 Protein Pre-coupled Magnetic Beads HEK293
    • Involved Pathway
    • Protein Function
    • Interacting Protein
    • IL1RL1 Related Articles
    • IL1RL1 Related Gene Family

    IL1RL1 involved in several pathways and played different roles in them. We selected most pathways IL1RL1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with IL1RL1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    IL1RL1 has several biochemical functions, for example, cytokine receptor activity, interleukin-1 receptor activity, interleukin-33 binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IL1RL1 itself. We selected most functions IL1RL1 had, and list some proteins which have the same functions with IL1RL1. You can find most of the proteins on our site.

    Function Related Protein
    cytokine receptor activityGHR;IL2RGB;CD74;LIFRB;IL4R.1;Il6ra;CRFB2;IL28RA;IL20RA
    interleukin-1 receptor activityIL1RAP;IL1RL2;IL1R2;IL1R1;IL18R1;IL1RAPL2;IL1RAPL1A;IL1RL1
    interleukin-33 binding
    interleukin-33 receptor activity
    protein bindingARAP3;PSMG1;FAM107A;COG4;ALOX12;THOC2;EIF2S1;BCL6;EIF2A
    receptor signaling protein activityPLCE1;DOK1;PLCG1;CD19;FLRT2;ARF1;DAXX;FLRT3;NCR1

    IL1RL1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IL1RL1 here. Most of them are supplied by our site. Hope this information will be useful for your research of IL1RL1.

    CLEC7A; IL33; MYD88; IRAK4; TRAF6

    Seeber, S; Ros, F; et al. A Robust High Throughput Platform to Generate Functional Recombinant Monoclonal Antibodies Using Rabbit B Cells from Peripheral Blood. PLOS ONE 9:-(2014).
    Gillibert-Duplantier, J; Duthey, B; et al. Gene expression profiling identifies sST2 as an effector of ErbB2-driven breast carcinoma cell motility, associated with metastasis. ONCOGENE 31:3516-3524(2012).
    • Q&As
    • Reviews

    Q&As (10)

    Ask a question
    Are there any splice variants of IL1RL1? 02/20/2022

    IL1RL1 has multiple splice variants that differ in signaling capabilities.

    What is the role of IL1RL1 in allergic responses? 11/15/2021

    IL1RL1 suppresses allergic responses by inhibiting mast cell activation.

    Does IL1RL1 have a role in autoimmune diseases? 10/09/2021

    IL1RL1 is implicated in rheumatoid arthritis.

    How does IL1RL1 affect cytokine production? 11/21/2020

    IL1RL1 increases the production of IL-4 and IL-13.

    What is the subcellular localization of IL1RL1? 08/13/2020

    IL1RL1 is primarily membrane-bound.

    Does IL1RL1 influence T-cell differentiation? 02/29/2020

    IL1RL1 promotes Th2 cell differentiation.

    How does IL1RL1 interact with its ligands? 01/17/2020

    IL1RL1 binds to IL-33 and IL-36 to initiate signaling.

    Is IL1RL1 expression altered in any cancers? 05/09/2018

    IL1RL1 expression is altered in lung and breast cancer.

    What post-translational modifications occur on IL1RL1? 03/28/2017

    IL1RL1 undergoes glycosylation and phosphorylation.

    How is IL1RL1 expression regulated in asthmatic conditions? 08/23/2016

    IL1RL1 expression is upregulated in asthmatic conditions.

    Customer Reviews (3)

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      High specificity in ELISA. -


        Suitable for flow cytometry. -


          Effective in allergy models. -

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