IL1RL1
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Official Full Name
interleukin 1 receptor-like 1 -
Overview
The protein encoded by this gene is a member of the interleukin 1 receptor family. Studies of the similar gene in mouse suggested that this receptor can be induced by proinflammatory stimuli, and may be involved in the function of helper T cells. This gene, interleukin 1 receptor, type I (IL1R1), interleukin 1 receptor, type II (IL1R2) and interleukin 1 receptor-like 2 (IL1RL2) form a cytokine receptor gene cluster in a region mapped to chromosome 2q12. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008] -
Synonyms
IL1RL1;interleukin 1 receptor-like 1;T1;ST2;DER4;ST2L;ST2V;FIT-1;IL33R;interleukin-1 receptor-like 1;growth stimulation-expressed;interleukin 1 receptor-related protein;homolog of mouse growth stimulation-expressed
Recombinant Proteins
- Human
- Mouse
- Chicken
- Rat
- Cynomolgus
- Mus musculus
- HEK293
- Mammalian Cells
- CHO
- Human Cells
- E.coli
- Sf21 Cells
- Human
- Rabbit
- His
- Non
- Fc
- T7
- Flag
- Avi
Involved Pathway
IL1RL1 involved in several pathways and played different roles in them. We selected most pathways IL1RL1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with IL1RL1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
IL1RL1 has several biochemical functions, for example, cytokine receptor activity,interleukin-1 receptor activity,interleukin-33 binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IL1RL1 itself. We selected most functions IL1RL1 had, and list some proteins which have the same functions with IL1RL1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | IL1RN,FNTB,DRAXIN,BDKRB2,KCNIP1,OBFC1,LEO1,LSM5,C12orf49,KIF6 |
| interleukin-1 receptor activity | IL18R1,IL1RAP,IL1R2,IL1R1,IL1RAPL1A,IL1RAPL2,IL1RL2 |
| receptor signaling protein activity | NSMAF,NGF,FLRT3,FLRT1,PLCE1,BAG1,TIAM2,Siglece,TGFBR1,BAG4 |
| cytokine receptor activity | CRFB15,IRX1,IL2RGB,IL17RB,IL20RB,LEPR,F3B,IL4R.1,LIFRB,IL12B |
Interacting Protein
IL1RL1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IL1RL1 here. Most of them are supplied by our site. Hope this information will be useful for your research of IL1RL1.
CLEC7A;IL33;MYD88;IRAK4;TRAF6
Resources
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References
- Seeber, S; Ros, F; et al. A Robust High Throughput Platform to Generate Functional Recombinant Monoclonal Antibodies Using Rabbit B Cells from Peripheral Blood. PLOS ONE 9:-(2014).
- Gillibert-Duplantier, J; Duthey, B; et al. Gene expression profiling identifies sST2 as an effector of ErbB2-driven breast carcinoma cell motility, associated with metastasis. ONCOGENE 31:3516-3524(2012).
