Recombinant Human IL1RL1 protein, Fc-tagged
Cat.No. : | IL1RL1-773H |
Product Overview : | Recombinant Human IL1RL1 protein (Lys19-Pro323), fused to human IgG1 Fc tag at C-terminus, was expressed in human 293 cells (HEK293). |
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Description : | Interleukin 1 receptor-like 1 (IL1RL1) is also known as ST2, DER4, FIT-1, IL33R, ST2L, ST2V, which belongs to the interleukin-1 receptor family. IL1RL1 contains three Ig-like C2-type (immunoglobulin-like) domains and one TIR domain. IL1RL1 is receptor for interleukin-33 (IL-33), its stimulation recruits MYD88, IRAK1, IRAK4, and TRAF6, followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2, MAPK14, and MAPK8. IL1RL1 possibly involved in helper T-cell function. IL1RL1 can interact with MYD88, IRAK1, IRAK4, and TRAF6. |
Source : | HEK293 |
Species : | Human |
Tag : | Fc |
Form : | Lyophilized from 0.22 um filtered solution in Tris with Glycine, Arginine and NaCl, pH7.5, 10% trehalose. |
Molecular Mass : | The protein has a calculated MW of 61.0 kDa. The protein migrates as 80-100 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Protein length : | 305 |
Endotoxin : | Less than 1.0 EU per ug by the LAL method. |
Purity : | >95% as determined by SDS-PAGE. |
Storage : | For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: -20 centigrade to -70 centigrade for 12 months in lyophilized state; -70 centigrade for 3 months under sterile conditions after reconstitution. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents. |
Gene Name : | IL1RL1 |
Official Symbol : | IL1RL1 |
Synonyms : | IL1RL1; interleukin 1 receptor-like 1; interleukin-1 receptor-like 1; DER4; FIT 1; homolog of mouse growth stimulation expressed; IL33R; ST2; ST2L; ST2V; T1; growth stimulation-expressed; interleukin 1 receptor-related protein; homolog of mouse growth stimulation-expressed; FIT-1; MGC32623 |
Gene ID : | 9173 |
mRNA Refseq : | NM_003856 |
Protein Refseq : | NP_003847 |
MIM : | 601203 |
UniProt ID : | Q01638 |
Products Types
◆ Recombinant Protein | ||
IL1RL1-774H | Active Recombinant Human IL1RL1 protein(Met1-Phe328), hFc-tagged | +Inquiry |
IL1RL1-1009H | Active Recombinant Human ST2 Protein | +Inquiry |
IL1RL1-195H | Recombinant Human IL1RL1 Protein, His (Fc)-Avi-tagged | +Inquiry |
IL1RL1-536H | Recombinant Human IL1RL1 protein, His-tagged | +Inquiry |
IL1RL1-775H | Recombinant Human IL1RL1 protein(Met1-Phe328) | +Inquiry |
◆ Lysates | ||
IL1RL1-2481HCL | Recombinant Human IL1RL1 cell lysate | +Inquiry |
IL1RL1-1883HCL | Recombinant Human IL1RL1 cell lysate | +Inquiry |
IL1RL1-001MCL | Recombinant Mouse IL1RL1 cell lysate | +Inquiry |
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Not For Human Consumption!
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Customer Reviews (3)
Write a reviewHigh specificity in ELISA.
Suitable for flow cytometry.
Effective in allergy models.
Q&As (10)
Ask a questionIL1RL1 has multiple splice variants that differ in signaling capabilities.
IL1RL1 suppresses allergic responses by inhibiting mast cell activation.
IL1RL1 is implicated in rheumatoid arthritis.
IL1RL1 increases the production of IL-4 and IL-13.
IL1RL1 is primarily membrane-bound.
IL1RL1 promotes Th2 cell differentiation.
IL1RL1 binds to IL-33 and IL-36 to initiate signaling.
IL1RL1 expression is altered in lung and breast cancer.
IL1RL1 undergoes glycosylation and phosphorylation.
IL1RL1 expression is upregulated in asthmatic conditions.
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