Active Recombinant Human IL1RL1, Fc-tagged
Cat.No. : | IL1RL1-502H |
Product Overview : | Signal peptide and the sequence of isoform 2 of human ST2 (aa 1-328) are fused at the C-terminus to the Fc portion of human IgG1. |
- Specification
- Gene Information
- Related Products
Description : | The ST2 (Interleukin-1 receptor-like 1; Interleukin-33 receptor) gene was originally identified as a gene induced by serum or oncogene expression in fibroblasts. The gene produces a shorter soluble secreted form (ST2) and a longer, transmembrane form (ST2L) by alternative splicing. Soluble ST2 has been shown to downregulate the expression of TLR1 and TLR4. ST2L negatively regulates TLR4 signaling and induces endotoxin tolerance, and enhances Th2 responses. IL-33 is the specific ligand for ST2L. |
Source : | HEK293 Cells |
Species : | Human |
Tag : | Fc |
Form : | Liquid. 0.2μm-filtered solution in PBS, pH 7.2. |
Bio-activity : | Interacts with human IL-33. |
Molecular Mass : | ~90kDa (SDS-PAGE) |
Purity : | ≥90% (SDS-PAGE) |
Stability : | Working aliquots are stable for up to 3 months when stored at -20°C. |
Storage : | Short Term Storage: +4°C; Long Term Storage: -20°C. After opening, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles. For maximum product recovery after thawing, centrifuge the vial before opening the cap. |
Concentration : | ~0.5mg/ml |
Gene Name : | IL1RL1 interleukin 1 receptor-like 1 [ Homo sapiens ] |
Official Symbol : | IL1RL1 |
Synonyms : | IL1RL1; interleukin 1 receptor-like 1; interleukin-1 receptor-like 1; DER4; FIT 1; homolog of mouse growth stimulation expressed; IL33R; ST2; ST2L; ST2V; T1; growth stimulation-expressed; interleukin 1 receptor-related protein; homolog of mouse growth stimulation-expressed; FIT-1; MGC32623; |
Gene ID : | 9173 |
mRNA Refseq : | NM_003856 |
Protein Refseq : | NP_003847 |
MIM : | 601203 |
UniProt ID : | Q01638 |
Chromosome Location : | 2q12 |
Function : | cytokine receptor activity; interleukin-1 receptor activity; interleukin-33 binding; protein binding; receptor activity; receptor signaling protein activity; |
Products Types
◆ Recombinant Protein | ||
IL1RL1-317H | Recombinant Human IL1RL1 Protein, His-tagged | +Inquiry |
IL1RL1-774H | Active Recombinant Human IL1RL1 protein(Met1-Phe328), hFc-tagged | +Inquiry |
IL1RL1-1009H | Active Recombinant Human ST2 Protein | +Inquiry |
IL1RL1-318H | Recombinant Human IL1RL1 Protein, Fc-tagged | +Inquiry |
IL1RL1-195H | Recombinant Human IL1RL1 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
IL1RL1-001MCL | Recombinant Mouse IL1RL1 cell lysate | +Inquiry |
IL1RL1-2481HCL | Recombinant Human IL1RL1 cell lysate | +Inquiry |
IL1RL1-1883HCL | Recombinant Human IL1RL1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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